Browse result page of PRRDB 2.0

PRRIDName of LigandSource of ligandSequence of LigandLength of Ligand Type of Ligand OccurenceRole of LigandName of ReceptorType of ReeptorSource of the ReceptorLocalizationDomainSequence of ReceptorSwiss prot IDLength of receptorFunction of ReceptorAssay usedPMIDYear of publicationPubchem assay
PRRID_2167HMGB1

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Endogenous (others)MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalan autocine trophic factor in ischemic ol death and white matter injuryToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Humanwhite matterLeucine-rich Repeat (LRR) DomainO60603.fastaO60603784executors for post-ischemic inflammation after interaction with danger associated molecular pattern protein (DAMP)NA289126412017Pubchem_assay
PRRID_2167HMGB1

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Endogenous (others)MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalan autocine trophic factor in ischemic ol death and white matter injuryToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Humanwhite matterLeucine-rich Repeat (LRR) DomainO60603.fastaO60603784executors for post-ischemic inflammation after interaction with danger associated molecular pattern protein (DAMP)NA289126412017Pubchem_assay
PRRID_2168HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalpromoting neuroinflammationToll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanNALeucine-rich Repeat (LRR) DomainO60603.fastaO60603784Activate NF-KBNA280491422017Pubchem_assay
PRRID_2168HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalpromoting neuroinflammationToll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanNALeucine-rich Repeat (LRR) DomainO60603.fastaO60603784Activate NF-KBNA280491422017Pubchem_assay
PRRID_2169HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalpromoting neuroinflammationToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanNALeucine-rich Repeat (LRR) DomainO00206.fastaO00206839Activate NF-KBNA280491422017Pubchem_assay
PRRID_2169HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalpromoting neuroinflammationToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanNALeucine-rich Repeat (LRR) DomainO00206.fastaO00206839Activate NF-KBNA280491422017Pubchem_assay
PRRID_2170HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalpromoting neuroinflammationToll-like receptor 9 (TLR9)Toll-like receptor (TLR)HumanNALeucine-rich Repeat (LRR) DomainQ9NR96.fastaQ9NR961032Activate NF-KBNA280491422017Pubchem_assay
PRRID_2170HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalpromoting neuroinflammationToll-like receptor 9 (TLR9)Toll-like receptor (TLR)HumanNALeucine-rich Repeat (LRR) DomainQ9NR96.fastaQ9NR961032Activate NF-KBNA280491422017Pubchem_assay
PRRID_2171HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalpromoting neuroinflammationcluster of differentiation 24 (CD24)Pattern recognition receptor (PRR)HumanNANAP25063.fastaP2506380Activate NF-KBNA280491422017Pubchem_assay
PRRID_2171HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalpromoting neuroinflammationcluster of differentiation 24 (CD24)Pattern recognition receptor (PRR)HumanNANAP25063.fastaP2506380Activate NF-KBNA280491422017Pubchem_assay
PRRID_2172HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalpromoting neuroinflammationRAGEReceptor for advanced glycation endproducts (RAGE)HumanNAaQ15109.fastaQ15109404Activate NF-KBNA280491422017Pubchem_assay
PRRID_2172HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalpromoting neuroinflammationRAGEReceptor for advanced glycation endproducts (RAGE)HumanNAaQ15109.fastaQ15109404Activate NF-KBNA280491422017Pubchem_assay
PRRID_2173HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalPromote human monocyte recruitmentToll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanMonocyteNAO60603.fastaO60603784NANA289610192017Pubchem_assay
PRRID_2173HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalPromote human monocyte recruitmentToll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanMonocyteNAO60603.fastaO60603784NANA289610192017Pubchem_assay
PRRID_2174HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalPromote human monocyte recruitmentToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanMonocyteNAO00206.fastaO00206839NANA289610192017Pubchem_assay
PRRID_2174HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalPromote human monocyte recruitmentToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanMonocyteNAO00206.fastaO00206839NANA289610192017Pubchem_assay
PRRID_2175HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalActivate the NF-κB pathway in murine embryonic fibrablasts.Toll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)Embryonic fibroblastNAQ9QUN7.fastaQ9QUK7511NANA289610192017Pubchem_assay
PRRID_2175HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalActivate the NF-κB pathway in murine embryonic fibrablasts.Toll-like receptor 2 (TLR2)Toll-like receptor (TLR)Mice (Murine)Embryonic fibroblastNAQ9QUN7.fastaQ9QUK7511NANA289610192017Pubchem_assay
PRRID_2176HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalActivate the NF-κB pathway in murine embryonic fibrablasts.Toll-like receptor 4 (TLR4)Toll-like receptor (TLR)Mice (Murine)Embryonic fibroblastNAQ9QUK6.fastaQ9QUK6835NANA289610192017Pubchem_assay
PRRID_2176HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalActivate the NF-κB pathway in murine embryonic fibrablasts.Toll-like receptor 4 (TLR4)Toll-like receptor (TLR)Mice (Murine)Embryonic fibroblastNAQ9QUK6.fastaQ9QUK6835NANA289610192017Pubchem_assay
PRRID_2177HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalInduce the expression of the cytokines TNF-α, IL-6 and IL-8 by human macrophages.Toll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanMacrophagesNAO60603.fastaO60603784NANA289610192017Pubchem_assay
PRRID_2177HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalInduce the expression of the cytokines TNF-α, IL-6 and IL-8 by human macrophages.Toll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanMacrophagesNAO60603.fastaO60603784NANA289610192017Pubchem_assay
PRRID_2178HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalInduce the expression of the cytokines TNF-α, IL-6 and IL-8 by human macrophages.Toll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanMacrophagesNAO00206.fastaO00206839NANA289610192017Pubchem_assay
PRRID_2178HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalInduce the expression of the cytokines TNF-α, IL-6 and IL-8 by human macrophages.Toll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanMacrophagesNAO00206.fastaO00206839NANA289610192017Pubchem_assay
PRRID_2179HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalInduce the expression of the cytokines TNF-α, IL-6 and IL-8 by human macrophages.RAGEReceptor for advanced glycation endproducts (RAGE)HumanMacrophagesNAQ15109.fastaQ15109404NANA289610192017Pubchem_assay
PRRID_2179HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalInduce the expression of the cytokines TNF-α, IL-6 and IL-8 by human macrophages.RAGEReceptor for advanced glycation endproducts (RAGE)HumanMacrophagesNAQ15109.fastaQ15109404NANA289610192017Pubchem_assay
PRRID_2180HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalPromote human monocyte recruitmentRAGEReceptor for advanced glycation endproducts (RAGE)HumanMonocyteNAQ15109.fastaQ15109404NANA289610192017Pubchem_assay
PRRID_2180HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalPromote human monocyte recruitmentRAGEReceptor for advanced glycation endproducts (RAGE)HumanMonocyteNAQ15109.fastaQ15109404NANA289610192017Pubchem_assay
PRRID_2181HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Micebrain (mononuclear phagocytes)Leucine-rich Repeat (LRR) DomainQ9QUN7.fastaQ9QUN7784mRNA ‚Üë in agingNA288015212017Pubchem_assay
PRRID_2181HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Micebrain (mononuclear phagocytes)Leucine-rich Repeat (LRR) DomainQ9QUN7.fastaQ9QUN7784mRNA ‚Üë in agingNA288015212017Pubchem_assay
PRRID_2182HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceBrainLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835mRNA ‚Üë in agingNA288015212017Pubchem_assay
PRRID_2182HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceBrainLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835mRNA ‚Üë in agingNA288015212017Pubchem_assay
PRRID_2183HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceBrainLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835mRNA ‚Üë in plaque- associated brain tissue of AD model miceNA288015212017Pubchem_assay
PRRID_2183HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceBrainLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835mRNA ‚Üë in plaque- associated brain tissue of AD model miceNA288015212017Pubchem_assay
PRRID_2184HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanbrain(hippocampus, superior frontal gyrus, post-central gyrus)Leucine-rich Repeat (LRR) DomainO00206.fastaO00206839mRNA ‚Üë in aging and ADNA288015212017Pubchem_assay
PRRID_2184HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanbrain(hippocampus, superior frontal gyrus, post-central gyrus)Leucine-rich Repeat (LRR) DomainO00206.fastaO00206839mRNA ‚Üë in aging and ADNA288015212017Pubchem_assay
PRRID_2185HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceMicrogliaLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835involved in both amyloid-β uptake and inflammatory cytokine productionNA288015212017Pubchem_assay
PRRID_2185HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceMicrogliaLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835involved in both amyloid-β uptake and inflammatory cytokine productionNA288015212017Pubchem_assay
PRRID_2186HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Micemicroglia (mouse striatum)Leucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835TLR4 knockout: neuroprotective in ischemiaNA288015212017Pubchem_assay
PRRID_2186HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Micemicroglia (mouse striatum)Leucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835TLR4 knockout: neuroprotective in ischemiaNA288015212017Pubchem_assay
PRRID_2187HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Miceneurons (mouse cortex)Leucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835protein ‚Üë, proapoptotic in ischemiaNA288015212017Pubchem_assay
PRRID_2187HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Miceneurons (mouse cortex)Leucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835protein ‚Üë, proapoptotic in ischemiaNA288015212017Pubchem_assay
PRRID_2188HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Ratrat brain (vasculature)Leucine-rich Repeat (LRR) DomainQ9QX05.fastaQ9QX05835protein ‚Üë, activation in ischemic strokeNA288015212017Pubchem_assay
PRRID_2188HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Ratrat brain (vasculature)Leucine-rich Repeat (LRR) DomainQ9QX05.fastaQ9QX05835protein ‚Üë, activation in ischemic strokeNA288015212017Pubchem_assay
PRRID_2189HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Miceprimary mouse astrocytesLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835activation in response to α-synucleinNA288015212017Pubchem_assay
PRRID_2189HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Miceprimary mouse astrocytesLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835activation in response to α-synucleinNA288015212017Pubchem_assay
PRRID_2190HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceBrainLeucine-rich Repeat (LRR) DomainQ9QUN7.fastaQ9QUN7784mRNA ‚Üë in plaque- associated brain tissue of AD model miceNA288015212017Pubchem_assay
PRRID_2190HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceBrainLeucine-rich Repeat (LRR) DomainQ9QUN7.fastaQ9QUN7784mRNA ‚Üë in plaque- associated brain tissue of AD model miceNA288015212017Pubchem_assay
PRRID_2191HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Humanbrain (hippocampus, entorhinal cortex, superior frontal gyrus, post-central gyrus)Leucine-rich Repeat (LRR) DomainO60603.fastaO60603784mRNA ‚Üë in aging and ADNA288015212017Pubchem_assay
PRRID_2191HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Humanbrain (hippocampus, entorhinal cortex, superior frontal gyrus, post-central gyrus)Leucine-rich Repeat (LRR) DomainO60603.fastaO60603784mRNA ‚Üë in aging and ADNA288015212017Pubchem_assay
PRRID_2192HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Ratrat hippocampus (microglia)Leucine-rich Repeat (LRR) DomainQ6YGU2.fastaQ6YGU2784mRNA ‚Üë in postoperative cognitive dysfunction in senile animalsNA288015212017Pubchem_assay
PRRID_2192HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Ratrat hippocampus (microglia)Leucine-rich Repeat (LRR) DomainQ6YGU2.fastaQ6YGU2784mRNA ‚Üë in postoperative cognitive dysfunction in senile animalsNA288015212017Pubchem_assay
PRRID_2193HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceMicrogliaLeucine-rich Repeat (LRR) DomainQ9QUN7.fastaQ9QUN7784involved in both amyloid-β uptake and inflammatory cytokine productionNA288015212017Pubchem_assay
PRRID_2193HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceMicrogliaLeucine-rich Repeat (LRR) DomainQ9QUN7.fastaQ9QUN7784involved in both amyloid-β uptake and inflammatory cytokine productionNA288015212017Pubchem_assay
PRRID_2194HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Humanhuman brain(neurons)Leucine-rich Repeat (LRR) DomainO60603.fastaO60603784protein ‚Üë in PDNA288015212017Pubchem_assay
PRRID_2194HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Humanhuman brain(neurons)Leucine-rich Repeat (LRR) DomainO60603.fastaO60603784protein ‚Üë in PDNA288015212017Pubchem_assay
PRRID_2195HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Miceneurons (mouse cortex)Leucine-rich Repeat (LRR) DomainQ9QUN7.fastaQ9QUN7784protein ‚Üë, proapoptotic in ischemiaNA288015212017Pubchem_assay
PRRID_2195HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Miceneurons (mouse cortex)Leucine-rich Repeat (LRR) DomainQ9QUN7.fastaQ9QUN7784protein ‚Üë, proapoptotic in ischemiaNA288015212017Pubchem_assay
PRRID_2196HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Ratrat brain (vasculature)Leucine-rich Repeat (LRR) DomainQ6YGU2.fastaQ6YGU2784protein ‚Üë, activation in ischemic strokeNA288015212017Pubchem_assay
PRRID_2196HMGB1

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NAMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE215ProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Ratrat brain (vasculature)Leucine-rich Repeat (LRR) DomainQ6YGU2.fastaQ6YGU2784protein ‚Üë, activation in ischemic strokeNA288015212017Pubchem_assay
PRRID_2228Lipopeptides or lipoteichoic acid (LTA)

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BacteriaC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)ONAProteinNaturalNAToll-like receptor (TLR1/Toll-like receptor 2 (TLR2) or Toll-like receptor 6 (TLR6)/ Toll-like recepToll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2228Lipopeptides or lipoteichoic acid (LTA)

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BacteriaC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)ONAProteinNaturalNAToll-like receptor (TLR1/Toll-like receptor 2 (TLR2) or Toll-like receptor 6 (TLR6)/ Toll-like recepToll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2313ATP

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BacteriaC1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)ONAProteinNaturalNANALP3/ cryopyrinNOD-like receptor (NLR)NANANANANANANANA280630152017NA
PRRID_2313ATP

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BacteriaC1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)ONAProteinNaturalNANALP3/ cryopyrinNOD-like receptor (NLR)NANANANANANANANA280630152017NA
PRRID_2445NA

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S. mansoni (others)NANAProteinNaturalNAhemoglobin-2non-canonical proteins interacting with pathogens (NCIP),NANANANANANANANA290517622017NA
PRRID_2445NA

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S. mansoni (others)NANAProteinNaturalNAhemoglobin-2non-canonical proteins interacting with pathogens (NCIP),NANANANANANANANA290517622017NA
PRRID_2446NA

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S. mansoni (others)NANAProteinNaturalNAα-amylasesenzymes interacting with pathogens (EIP)B. glabRataNANANANANANANA290517622017NA
PRRID_2446NA

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S. mansoni (others)NANAProteinNaturalNAα-amylasesenzymes interacting with pathogens (EIP)B. glabRataNANANANANANANA290517622017NA
PRRID_2496NEMO

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VirusNANAProteinNaturalNAADAP2Pattern recognition receptor (PRR)NANANANANANANANA279567052017NA
PRRID_2496NEMO

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VirusNANAProteinNaturalNAADAP2Pattern recognition receptor (PRR)NANANANANANANANA279567052017NA
PRRID_2504TBK1

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VirusNANAProteinNaturalNAADAP2Pattern recognition receptor (PRR)NANANANANANANANA279567052017NA
PRRID_2504TBK1

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VirusNANAProteinNaturalNAADAP2Pattern recognition receptor (PRR)NANANANANANANANA279567052017NA
PRRID_2505 IRF3

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VirusNANAProteinNaturalNAADAP2Pattern recognition receptor (PRR)NANANANANANANANA279567052017NA
PRRID_2505 IRF3

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VirusNANAProteinNaturalNAADAP2Pattern recognition receptor (PRR)NANANANANANANANA279567052017NA
PRRID_2538Peptidoglycan (PG) (Legionella recognized)

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BacteriaNANAProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2538Peptidoglycan (PG) (Legionella recognized)

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BacteriaNANAProteinNaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2551PG-derived molecules (iE-DAP and MDP respectively

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BacteriaN[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=ONAProteinNaturalNANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)NANANANANANANANA280630152017NA
PRRID_2551PG-derived molecules (iE-DAP and MDP respectively

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BacteriaN[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=ONAProteinNaturalNANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)NANANANANANANANA280630152017NA
PRRID_2576Profilin and bacterial rRNA respectively (not found in humans)

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BacteriaNANAProteinNaturalNAToll-like receptor 12 (TLR12)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2576Profilin and bacterial rRNA respectively (not found in humans)

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BacteriaNANAProteinNaturalNAToll-like receptor 12 (TLR12)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2577Profilin and bacterial rRNA respectively (not found in humans)

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BacteriaNANAProteinNaturalNAToll-like receptor 13 (TLR13)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2577Profilin and bacterial rRNA respectively (not found in humans)

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BacteriaNANAProteinNaturalNAToll-like receptor 13 (TLR13)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2578profilin-like protein

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T. gondii (others)MSDWDPVVKEWLVDTGYCCAGGIANVSAEDGVVFAAAADDDDGWSKLYKDDHEEDTIGEDGNACGKVSINEASTIKAAVDDGSAPNGVWIGGQKYKVVRPEKGFEYNDCTFDITMCARSKGGAHLIKTPNGSIVIALYDEEKEQDKGNSRTSALAFAEYLHQSGY165ProteinNaturalNAToll-like receptor 10 (TLR10)Toll-like receptor (TLR)HumanNALeucine-rich Repeat (LRR) DomainNANANANANA292639322017NA
PRRID_2578profilin-like protein

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T. gondii (others)MSDWDPVVKEWLVDTGYCCAGGIANVSAEDGVVFAAAADDDDGWSKLYKDDHEEDTIGEDGNACGKVSINEASTIKAAVDDGSAPNGVWIGGQKYKVVRPEKGFEYNDCTFDITMCARSKGGAHLIKTPNGSIVIALYDEEKEQDKGNSRTSALAFAEYLHQSGY165ProteinNaturalNAToll-like receptor 10 (TLR10)Toll-like receptor (TLR)HumanNALeucine-rich Repeat (LRR) DomainNANANANANA292639322017NA
PRRID_2633spliceosome- associated protein 130

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NANANAProteinNaturalelicit innate immune responseMincleC type Lectin (CTL/CLR)NANANANANANANANA288015212017NA
PRRID_2633spliceosome- associated protein 130

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NANANAProteinNaturalelicit innate immune responseMincleC type Lectin (CTL/CLR)NANANANANANANANA288015212017NA
PRRID_2636Staphylococcus aureus

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Gram-positive bacteriaNANAProteinNaturalelicit innate immune responsePmCLecC type Lectin (CTL/CLR)NANANANANANANANA278766222017NA
PRRID_2636Staphylococcus aureus

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Gram-positive bacteriaNANAProteinNaturalelicit innate immune responsePmCLecC type Lectin (CTL/CLR)NANANANANANANANA278766222017NA
PRRID_2639 S. Hemolyticus

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Gram-positive bacteriaNANAProteinNaturalelicit innate immune responsePmCLecC type Lectin (CTL/CLR)NANANANANANANANA278766222017NA
PRRID_2639 S. Hemolyticus

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Gram-positive bacteriaNANAProteinNaturalelicit innate immune responsePmCLecC type Lectin (CTL/CLR)NANANANANANANANA278766222017NA
PRRID_2651The natural killer group 2D (NKG2D)

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NANANAProteinNaturalNAThe natural killer group 2D (NKG2D) receptorPattern recognition receptor (PRR)NANANANANANANANA289864472017NA
PRRID_2651The natural killer group 2D (NKG2D)

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NANANAProteinNaturalNAThe natural killer group 2D (NKG2D) receptorPattern recognition receptor (PRR)NANANANANANANANA289864472017NA
PRRID_2661Unknown

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BacteriaNANAProteinNaturalNATRl OToll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2661Unknown

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BacteriaNANAProteinNaturalNATRl OToll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2662Unknown (uropathogenic bacteria)

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BacteriaNANAProteinNaturalNAToll-like receptor (TLRll)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2662Unknown (uropathogenic bacteria)

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BacteriaNANAProteinNaturalNAToll-like receptor (TLRll)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2669Unmethylated CpG DNA

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BacteriaNANAProteinNaturalNAToll-like receptor 9 (TLR9)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2669Unmethylated CpG DNA

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BacteriaNANAProteinNaturalNAToll-like receptor 9 (TLR9)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2698β­glucan

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FungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAProteinNaturalNAcluster of differentiation 5 (CD5)Pattern recognition receptor (PRR)NAT cells and a small subset of mature B cells,NANANANANANA293589412017NA
PRRID_2698β­glucan

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FungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAProteinNaturalNAcluster of differentiation 5 (CD5)Pattern recognition receptor (PRR)NAT cells and a small subset of mature B cells,NANANANANANA293589412017NA