The Total number of records shown on this page is 24. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_2982	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2983	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	98% cell survival after 48 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2984	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	80% cell survival after 72 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2985	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	45% cell survival after 96 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2986	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	5% cell survival after 120 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2987	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	80% cell survival after 24 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2988	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	30% cell survival after 48 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2989	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	20% cell survival after 72 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2990	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	5% cell survival after 96 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2991	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	100% cell death after 120 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2992	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2993	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	98% cell survival after 48 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2994	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	70% cell survival after 72 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2995	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	70% cell survival after 96 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2996	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	20% cell survival after 120 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2997	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	80% cell survival after 24 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2998	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	40% cell survival after 48 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2999	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	20% cell survival after 72 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_3000	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	10% cell survival after 96 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_3001	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	100% cell death after 120 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_3002	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HCT-116	NA	NA	NA	NA	NA	Hsd:athymic nude mice xenograft for HCT-116 (2.0E+6 cells)	1.0E+5 pfu	NA	Complete regression in tumor volume after 55 days	Intratumoral	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_3003	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	NA	NA	NA	NA	NA	Hsd:athymic nude mice xenograft for HT-29 (5.0E+6 cells)	1.0E+5 pfu	NA	Tumor volume reached 1500mm after day 50	Intratumoral	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_3004	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	No	Virus in combination with I-131	No	ATCC	Human colorectal cancer cell line	HCT-116	NA	NA	NA	NA	NA	Hsd:athymic nude mice xenograft for HCT-116 (2.0E+6 cells)	1.0E+4 pfu	NA	Reduction in tumor volume below 100mm after 55 days	Intravenous	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_3005	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	No	Virus in combination with I-131	No	ATCC	Human colorectal cancer cell line	HT-29	NA	NA	NA	NA	NA	Hsd:athymic nude mice xenograft for HT-29 (3.0E+9 cells)	1.0E+4 pfu	NA	Reduction in tumor volume below 300mm after 45 days	Intravenous	Immunogenicity followed by virus induced cell death	NA	NA	31061881