Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_5596Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman lung carcinoma cell lineH-129980% confluencyNAMTT assay26 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5597Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman lung carcinoma cell lineA42780% confluencyNAMTT assay2 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5598Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman lung carcinoma cell lineA54980% confluencyNAMTT assay13 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5599Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman melanoma cell lineSK-MEL-280% confluencyNAMTT assay8 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5600Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman melanoma cell lineSKMEL-380% confluencyNAMTT assay2 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5601Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman melanoma cell lineSKMEL-580% confluencyNAMTT assay4 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5602Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman melanoma cell lineA37580% confluencyNAMTT assay37 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5603Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman melanoma cell lineMALME-3M80% confluencyNAMTT assay778 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5604Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman melanoma cell lineHT14480% confluencyNAMTT assay28 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5605Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman breast carcinoma cell lineSKNR380% confluencyNAMTT assay10 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5606Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman breast carcinoma cell lineMDA-MB-46880% confluencyNAMTT assay44 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5607Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman breast carcinoma cell lineZR75-180% confluencyNAMTT assay78 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5608Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian sarcoma cell lineSW62680% confluencyNAMTT assay4 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5609Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian sarcoma cell linePA-180% confluencyNAMTT assay4 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5610Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian sarcoma cell lineES-280% confluencyNAMTT assay13 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5611Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian sarcoma cell lineSKOV380% confluencyNAMTT assay24 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5612Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian sarcoma cell lineOVCAR380% confluencyNAMTT assay34 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5613Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman glioblastoma cell lineU-87 MG80% confluencyNAMTT assay25 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5614Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman glioblastoma cell lineU373MG80% confluencyNAMTT assay765 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5615Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman glioblastoma cell lineU13880% confluencyNAMTT assay38 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5616Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman glioblastoma cell lineA17280% confluencyNAMTT assay207 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5617Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman bladder carcinomaHT119780% confluencyNAMTT assay3 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5618Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman bladder carcinomaUM-UC-380% confluencyNAMTT assay54 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5619Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman bladder carcinomaHT136780% confluencyNAMTT assay422 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5620Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman neuroblastoma cell lineIMR-3280% confluencyNAMTT assay41 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5621Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman cervical carcinoma cell lineHeLa80% confluencyNAMTT assay4 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5622Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman prostate cancer cell lineDu14580% confluencyNAMTT assay31 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5623Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman prostate cancer cell linePC-380% confluencyNAMTT assay3×10³ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5624Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman colon carcinoma cell lineSW62080% confluencyNAMTT assay55 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5625Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman colon carcinoma cell lineHT-2980% confluencyNAMTT assay1 ×10⁶ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5626Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman head and neck carcinoma cell lineKB80% confluencyNAMTT assay4 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5627Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman carcinoma cell lineA25380% confluencyNAMTT assay2.7 ×10³ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5628Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman carcinoma cell lineFaDu80% confluencyNAMTT assay2.9 ×10³ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5629Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman carcinoma cell lineHep-280% confluencyNAMTT assay1.5 ×10⁴ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5630Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman neuroepithelioma cell lineSK-N-MC80% confluencyNAMTT assay20 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5631Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman small cell lung carcinoma cell lineDMS-11480% confluencyNAMTT assay48 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5632Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman small cell lung carcinoma cell lineDMS-15380% confluencyNAMTT assay1.1 ×10⁵ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5633Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman small cell lung carcinoma cell lineNCI-H34580% confluencyNAMTT assay1.2 ×10⁶ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5634Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman prostate small cell carcinomaNCI-H66080% confluencyNAMTT assay1.0 ×10⁵ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5635Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman leukemia cell lineK56280% confluencyNAMTT assay5.4 ×10⁴ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5636Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman lymphoma cell lineRamos80% confluencyNAMTT assay1 ×10⁶ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5637Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman lymphoma cell lineDaudi80% confluencyNAMTT assay1 ×10⁶ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5638Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for human fibroblast HT1080 (10 million)3.0E+8 pfuNA Complete regrression in tumor in 11 mice from complete 12 (tumor volume <10mm and >5 mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5639Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for human fibroblast HT1080 (10 million)3.0E+8 pfuNA Complete regrression in tumor in 8 mice from complete 9 (tumor volume <10mm and >5 mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5640Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for human fibroblast HT1080 (10 million)3.0E+8 pfuNA Complete regrression in tumor in all mice (tumor volume <10mm and >5 mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5641Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for human ovarian carcinoma PA-1 (10 million)3.0E+8 pfuNA Complete regrression in tumor in all mice (tumor volume <10mm and >5 mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5642Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for human oral carcinoma KB (10 million)3.0E+8 pfuNA Complete reduction in tumor in 7 mice from all 12 treated (tumor volume <10mm and >5 mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5643Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for human fmelanoma SKMEL (10 million)3.0E+8 pfuNA Complete reduction in tumor in 5 mice from all 8 treated (tumor volume <10mm and >5 mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5644Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for human lung carcinoma A375 (10 million)3.0E+8 pfuNA Complete reduction in tumor in 5 mice from all 8 treated (tumor volume <10mm and >5 mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5645Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for human lung carcinoma A375 (10 million)3.0E+8 pfuNA Complete regrression in tumor in all mice (tumor volume <10mm and >5 mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5646Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for humanglioblastoma U87MG (10 million)3.0E+8 pfuNA Complete reduction in tumor in 1 mice from all 9 treated (tumor volume <10mm and >5 mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5647Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for human fibroblast HT1080 (10 million)1.0E+9 pfuNA Complete regression in all tumor bearing mice (tumor volume <8.5 mm and > 5.5)IntravenouslyInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5648Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for human fibroblast HT1080 (10 million)3.0E+8 pfuNA Complete regression in all tumor bearing mice (tumor volume <8.5 mm and > 5.5)IntravenouslyInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5649Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for human fibroblast HT1080 (10 million)6.0E+7 pfuNA Complete regression in tumor volume in 10 mice out of 11 (tumor volume <8.5 mm and > 5.5)IntravenouslyInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5650Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for human fibroblast HT1080 (10 million)2.0E+7 pfuNA Complete regression in tumor volume in 5 mice out of 11 (tumor volume <8.5 mm and > 5.5)IntravenouslyInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5651Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for human fibroblast HT1080 (10 million)2.0E+7 pfuNA Complete regression in tumor volume in 5 mice out of 7 (tumor volume <8.5 mm and > 5.5)IntravenouslyInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5652Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)1.5E+9 pfuNA Complete regression in tumor in 2 mice from total 8 tretated (tumor dimension 8 - 9.5mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5653Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)9.0E+8 pfuNA Complete regression in tumor in 7 mice from total 8 tretated (tumor dimension 8 - 9.5mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5654Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)3.0E+8 pfuNA Complete regression in tumor in 3 mice from total 8 tretated (tumor dimension 8 - 9.5mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5655Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)1.5E+9 pfuNA Complete regression in tumor in 2 mice from total 6 tretated (tumor volume <300mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5656Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)9.0E+8 pfuNA Complete regression in tumor in 3 mice from total 4 tretated (tumor dimension <300mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5657Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)3.0E+8 pfuNA Complete regression in tumor in 2 mice from total 6 tretated (tumor volume <300mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5658Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)3.0E+8 pfuNA Complete regression in tumor in 3 mice from total 5 tretated (tumor volume >300mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5659Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)3.0E+8 pfuNA Complete regression in tumor in all mice(tumor volume >300mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5660Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)3.0E+8 pfuNA Complete regression in tumor in 4 mice from total 5 tretated (tumor volume>300mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5661Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)1.5E+9 pfuNA Complete regression in tumor in all mice (tumor dimension 10 - 11.5 mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5662Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)3.0E+8 pfuNA Complete regression in tumor in 6 mice from 7 (tumor dimension 10 - 11.5 mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5663Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)3.0E+7 pfuNA Complete regression in tumor in 5 mice from 7 (tumor dimension 10 - 11.5 mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5664Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)3.0E+6 pfuNA Complete regression in tumor in 5 mice from 7 (tumor dimension 10 - 11.5 mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5665Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)1.5E+9 pfuNA Complete regression in tumor in all mice (tumor volume >300mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5666Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)3.0E+8 pfuNA Complete reduction in tumor in 6 mice from 7 (tumor volume >300mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5667Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)3.0E+7 pfuNA Complete reduction in tumor in 4 mice from 6 (tumor volume >300mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5668Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNANANANANANANANAAthymic mice xenograft for A375 (10 million)3.0E+6 pfuNA Complete reduction in tumor in 4 mice from 6 (tumor volume >300mm)IntratumoralInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5817Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman fibrosarcoma cell lineHT108080% confluencyNANA2 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5818Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman melanoma cell lineSK-MEL-280% confluencyNANA8 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5819Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman melanoma cell lineSKMEL-380% confluencyNANA2 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5820Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman melanoma cell lineSKMEL-580% confluencyNANA4 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5821Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman melanoma cell lineA37580% confluencyNANA37 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5822Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman melanoma cell lineMALME-3M80% confluencyNANA778 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5823Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman melanoma cell lineHT14480% confluencyNANA28 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5824Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman breast carcinoma cell lineSKBR380% confluencyNANA10 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5825Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman breast carcinoma cell lineMDA-MB-46880% confluencyNANA44 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5826Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman breast carcinoma cell lineZR75-180% confluencyNANA78 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5827Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian carcinoma cell lineSW2680% confluencyNANA4 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5828Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian carcinoma cell linePA-180% confluencyNANA4 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5829Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian carcinoma cell lineES-280% confluencyNANA13 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5830Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian carcinoma cell lineSKOV380% confluencyNANA24 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5831Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian carcinoma cell lineOVCAR380% confluencyNANA34 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5832Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman lung adenocarcinoma cell lineH-129980% confluencyNANA26 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5833Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman glioblastoma cell lineU-87 MG80% confluencyNANA25 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5834Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman glioblastoma cell lineU373MG80% confluencyNANA765 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5835Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman glioblastoma cell lineU13880% confluencyNANA38 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5836Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman glioblastoma cell lineA17280% confluencyNANA207 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5837Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman bladder carcinoma cell lineHT119780% confluencyNANA3 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5838Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman bladder carcinoma cell lineUM-UC-380% confluencyNANA54 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5839Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman bladder carcinoma cell lineHT137680% confluencyNANA422 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5840Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman neuroblastoma cell lineIMR-3280% confluencyNANA41 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5841Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman cervical carcinoma cell lineHeLa80% confluencyNANA4 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5842Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman prostae carcinoma cell lineDu14580% confluencyNANA31 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5843Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman prostae carcinoma cell linePC-380% confluencyNANA3.1 ×10³ pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578