Primary information |
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OV_ID | OV_5627 |
Virus Name | Newcastle disease virus |
Strain | NDV-MK107 |
Virus type | RNA |
Virus family | Paramyxoviridae |
Modification in virus genome | None |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | NA |
Origin of cell line | Human carcinoma cell line |
Cell line | A253 |
Concentration of cell line | 80 |
In-vitro toxicity | NA |
Assay | MTT assay |
In-vitro virus concentration | 2.7 ×10³ pfu |
In-vitro result | 50% of cancer cell death occurs |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | Induction of apoptosis by virus infection |
Immunogenic effect | Induction of IFN-Gamma production |
Clinical trial | NA |
PMID | US7470426 |