Detailed description page of Selected OV_ID


OV_5649 details
Primary information
OV_IDOV_5649
Virus Name Newcastle disease virus
StrainNDV-MK107
Virus typeRNA
Virus familyParamyxoviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismAthymic mice xenograft for human fibroblast HT1080 (10 million)
In-vivo virus concentration6 ×10⁷ pfu
In-vivo toxicityNA
In-vivo resultComplete regression in tumor volume in 10 mice out of 11 (tumor volume <8.5 mm and > 5.5)
Mode of deliveryIntravenously
Pathway inductionInduction of apoptosis by virus infection
Immunogenic effectInduction of IFN-Gamma production
Clinical trialNA
PMIDUS7470426