The Total number of records shown on this page is 43. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_5412	Measles virus	Schwarz vaccine stain	RNA	Paramyxoviridae	None	Yes	No	No	ICCMGR cell bank unit, Iraq	Human glioblastoma cell line	ANGM5	7.0E+3 cells per well	NA	MTT assay	3.4 × 10⁵ pfu	35.279% cell growth inhibition after 120 hours	No	No	NA	No response	NA	Induction of apoptosis as measured by mitochondrial permeability apoptosis assay	NA	NA	27512663
OV_5430	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	KLM1	NA	NA	WST-1 assay	1 MOI	60% cell viable after day 2	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5431	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	KLM1	NA	NA	WST-1 assay	1 MOI	10% cell viable after day 4	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5432	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	KLM1	NA	NA	WST-1 assay	1 MOI	100% cell killing after day 6	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5433	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	KLM1	NA	NA	WST-1 assay	1 MOI	100% cell killing after day 8	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5434	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	KLM1	NA	NA	WST-1 assay	1 MOI	100% cell killing after day 10	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5435	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	Capan-2	NA	NA	WST-1 assay	1 MOI	100% cell viable after day 2	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5436	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	Capan-2	NA	NA	WST-1 assay	1 MOI	80% cell viable after day 4	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5437	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	Capan-2	NA	NA	WST-1 assay	1 MOI	70% cell viable after day 6	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5438	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	Capan-2	NA	NA	WST-1 assay	1 MOI	50% cell viable after day 8	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5439	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	Capan-2	NA	NA	WST-1 assay	1 MOI	40% cell viable after day 10	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5440	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PSN1	NA	NA	WST-1 assay	1 MOI	100% cell viable after day 2	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5441	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PSN1	NA	NA	WST-1 assay	1 MOI	100% cell viable after day 4	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5442	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PSN1	NA	NA	WST-1 assay	1 MOI	100% cell viable after day 6	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5443	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PSN1	NA	NA	WST-1 assay	1 MOI	90% cell viable after day 8	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5444	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PSN1	NA	NA	WST-1 assay	1 MOI	100% cell viable after day 10	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5445	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PK1	NA	NA	WST-1 assay	1 MOI	100% cell viable after day 2	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5446	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PK1	NA	NA	WST-1 assay	1 MOI	90% cell viable after day 4	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5447	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PK1	NA	NA	WST-1 assay	1 MOI	100% cell viable after day 6	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5448	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PK1	NA	NA	WST-1 assay	1 MOI	80% cell viable after day 8	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5449	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PK1	NA	NA	WST-1 assay	1 MOI	60% cell viable after day 10	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5450	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PK9	NA	NA	WST-1 assay	1 MOI	90% cell viable after day 2	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5451	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PK9	NA	NA	WST-1 assay	1 MOI	90% cell viable after day 4	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5452	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PK9	NA	NA	WST-1 assay	1 MOI	70% cell viable after day 6	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5453	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PK9	NA	NA	WST-1 assay	1 MOI	60% cell viable after day 8	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5454	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	Tohuku university Japan	Human pancreatic cancer cell line	PK9	NA	NA	WST-1 assay	1 MOI	60% cell viable after day 10	No	No	NA	No response	NA	NA	NA	NA	27561180
OV_5455	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	SCID mice xenograft for KLM	1.0E+6 TCID50	NA	Reduction in tumor volume to below 600 cubic mm after 90 days compared to control 2500 cubic mm	Intratumoral	NA	NA	NA	27561180
OV_5456	Measles virus	rMV-SLAMblind	RNA	Paramyxoviridae	R533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particle	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	SCID mice xenograft for Capan2	1.0E+6 TCID50	NA	Reduction in tumor volume to below 100 cubic mm after 45 days compared to control 1600 cubic mm	Intratumoral	NA	NA	NA	27561180
OV_5589	Measles virus	Measles virus edmon strain (MV-Edm)	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human myeloma cell line	ARH-77	NA	NA	NA	NA	NA	SCID mice xenograft for ARH-77	1.0E+7 pfu	NA	Complete reduction in tumor volume after 30 days when injected 1 dose	Intravenously	NA	NA	NA	US7393527
OV_5590	Measles virus	Measles virus edmon strain (MV-Edm)	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human myeloma cell line	ARH-77	NA	NA	NA	NA	NA	SCID mice xenograft for ARH-77	1.0E+7 pfu	NA	Complete reduction in tumor volume after 30 days when injected 7 dose alternative days	Intravenously	NA	NA	NA	US7393527
OV_5915	Measles virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human lung cancer cell line	ABC-1	NA	NA	WST-1 assay	1 MOI	60% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	US10335481
OV_5916	Measles virus	wild type	RNA	Paramyxoviridae	Mutated for SLAM binding	Yes	No	No	NA	Human lung cancer cell line	NCI-H441	NA	NA	WST-1 assay	1 MOI	Complete cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	US10335481
OV_5917	Measles virus	wild type	RNA	Paramyxoviridae	Mutated for SLAM binding	Yes	No	No	NA	Human lung cancer cell line	NCI-H2170	NA	NA	WST-1 assay	1 MOI	Complete cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	US10335481
OV_5918	Measles virus	wild type	RNA	Paramyxoviridae	Mutated for SLAM binding	Yes	No	No	NA	Human lung cancer cell line	NCI-H358	NA	NA	WST-1 assay	1 MOI	90% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	US10335481
OV_5919	Measles virus	wild type	RNA	Paramyxoviridae	Mutated for SLAM binding	Yes	No	No	NA	Human lung cancer cell line	Calu-3	NA	NA	WST-1 assay	1 MOI	70% cancer cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	US10335481
OV_5920	Measles virus	wild type	RNA	Paramyxoviridae	Mutated for SLAM binding	Yes	No	No	NA	Human lung cancer cell line	NCI-H1666	NA	NA	WST-1 assay	1 MOI	70% cancer cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	US10335481
OV_5921	Measles virus	wild type	RNA	Paramyxoviridae	Mutated for SLAM binding	Yes	No	No	NA	Human lung cancer cell line	PC-14	NA	NA	WST-1 assay	1 MOI	20% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	US10335481
OV_5922	Measles virus	wild type	RNA	Paramyxoviridae	Mutated for SLAM binding	Yes	No	No	NA	Human lung cancer cell line	A431	NA	NA	WST-1 assay	1 MOI	20% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	US10335481
OV_5923	Measles virus	wild type	RNA	Paramyxoviridae	Mutated for SLAM binding	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	SCID mice xenograft for NCI-H441(1.0E+8)	5.0E+7 pfu	NA	Reduction in tumor volume to 200mm compared to control 2500mm after 40 days	Intratumoral	NA	NA	NA	US10335481
OV_5924	Measles virus	wild type	RNA	Paramyxoviridae	Mutated for SLAM binding	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	SCID mice xenograft for NCI-H441(1.0E+8)	5.0E+7 pfu	NA	Significant reduction in tumor volume	Intravenously	NA	NA	NA	US10335481
OV_5925	Measles virus	wild type	RNA	Paramyxoviridae	Mutated for SLAM binding	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	SCID mice xenograft for DLDI(5.0E+6)	1.0E+6 TCID50	NA	Tumor volume reduced to below 400mm after 20 days	Intratumoral	NA	NA	NA	US10335481
OV_5926	Measles virus	wild type	RNA	Paramyxoviridae	Mutated for SLAM binding	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	SCID mice xenograft for HT29(5.0E+6)	1.0E+6 TCID50	NA	Tumor volume reduced to below 400mm after 20 days	Intratumoral	NA	NA	NA	US10335481
OV_5927	Measles virus	wild type	RNA	Paramyxoviridae	Mutated for SLAM binding	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	SCID mice xenograft for HCC70(5.0E+6)	1.0E+6 TCID50	NA	Tumor volume reduced to 200mm after 30 days	Intratumoral	NA	NA	NA	US10335481