Detailed description page of Selected OV_ID


OV_5923 details
Primary information
OV_IDOV_5923
Virus Name Measles virus
Strainwild type
Virus typeRNA
Virus familyParamyxoviridae
Modification in virus genomeMutated for SLAM binding
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismSCID mice xenograft for NCI-H441(1 ×10⁸)
In-vivo virus concentration5 ×10⁷ pfu
In-vivo toxicityNA
In-vivo resultReduction in tumor volume to 200mm compared to control 2500mm after 40 days
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMIDUS10335481