Detailed description page of Selected OV_ID


OV_5590 details
Primary information
OV_IDOV_5590
Virus Name Measles virus
StrainMeasles virus edmon strain (MV-Edm)
Virus typeRNA
Virus familyParamyxoviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineHuman myeloma cell line
Cell lineARH-77
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismSCID mice xenograft for ARH-77
In-vivo virus concentration1 ×10⁷ pfu
In-vivo toxicityNA
In-vivo resultComplete reduction in tumor volume after 30 days when injected 7 dose alternative days
Mode of deliveryIntravenously
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMIDUS7393527