Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_3220Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman bone osteosarcoma cell line143-B90% confluenceNACrystal violet staining and absorbance at 595 nm0.001 MOI73% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3221Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman bone osteosarcoma cell line143-B90% confluenceNACrystal violet staining and absorbance at 595 nm0.01 MOI60% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3222Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman bone osteosarcoma cell line143-B90% confluenceNACrystal violet staining and absorbance at 595 nm0.1 MOI55% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3223Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman bone osteosarcoma cell line143-B90% confluenceNACrystal violet staining and absorbance at 595 nm1 MOI50% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3224Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman bone osteosarcoma cell line143-B90% confluenceNACrystal violet staining and absorbance at 595 nm10 MOI40% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3249Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman canine osteosarcomaD1790% confluenceNACrystal violet staining and absorbance at 595 nm0.0001 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3250Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman canine osteosarcomaD1790% confluenceNACrystal violet staining and absorbance at 595 nm0.001 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3251Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman canine osteosarcomaD1790% confluenceNACrystal violet staining and absorbance at 595 nm0.01 MOI75% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3252Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman canine osteosarcomaD1790% confluenceNACrystal violet staining and absorbance at 595 nm0.1 MOI72% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3253Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman canine osteosarcomaD1790% confluenceNACrystal violet staining and absorbance at 595 nm1 MOI60% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3254Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman canine osteosarcomaD1790% confluenceNACrystal violet staining and absorbance at 595 nm10 MOI55% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3279Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman synovial sarcoma cell lineSW98290% confluenceNACrystal violet staining and absorbance at 595 nm0.0001 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3280Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman synovial sarcoma cell lineSW98290% confluenceNACrystal violet staining and absorbance at 595 nm0.001 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3281Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman synovial sarcoma cell lineSW98290% confluenceNACrystal violet staining and absorbance at 595 nm0.01 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3282Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman synovial sarcoma cell lineSW98290% confluenceNACrystal violet staining and absorbance at 595 nm0.1 MOI75% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3283Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman synovial sarcoma cell lineSW98290% confluenceNACrystal violet staining and absorbance at 595 nm1 MOI70% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3284Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman synovial sarcoma cell lineSW98290% confluenceNACrystal violet staining and absorbance at 595 nm10 MOI70% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3404Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNASRB assay0.001 MOINo cell killing after 72 hoursNoNoNA No responseNANANANA28607950
OV_3405Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNASRB assay0.005 MOINo cell killing after 72 hoursNoNoNA No responseNANANANA28607950
OV_3406Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNASRB assay0.01 MOINo cell killing after 72 hoursNoNoNA No responseNANANANA28607950
OV_3407Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNASRB assay0.05 MOI35% cell killing after 72 hoursNoNoNA No responseNANANANA28607950
OV_3408Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNASRB assay0.1 MOI30% cell killing after 72 hoursNoNoNA No responseNANANANA28607950
OV_3409Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNASRB assay0.1 MOINo cell killing after 72 hoursNoNoNA No responseNANANANA28607950
OV_3410Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNASRB assay0.25 MOINo cell killing after 72 hoursNoNoNA No responseNANANANA28607950
OV_3411Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNASRB assay0.5 MOINo cell killing after 72 hoursNoNoNA No responseNANANANA28607950
OV_3412Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNASRB assay0.75 MOI28% cell killing after 72 hoursNoNoNA No responseNANANANA28607950
OV_3413Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNASRB assay1 MOI25% cell killing after 72 hoursNoNoNA No responseNANANANA28607950
OV_3414Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNASRB assay0.01 MOINo cell killing after 72 hoursNoNoNA No responseNANANANA28607950
OV_3415Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNASRB assay0.05 MOI80% cell survival after 72 hoursNoNoNA No responseNANANANA28607950
OV_3416Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNASRB assay0.1 MOI75% cell survival after 72 hoursNoNoNA No responseNANANANA28607950
OV_3417Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNASRB assay0.5 MOI25% cell survival after 72 hoursNoNoNA No responseNANANANA28607950
OV_3418Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNASRB assay1 MOI10% cell survival after 72 hoursNoNoNA No responseNANANANA28607950
OV_3419Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNASRB assay0.01 MOINo cell killing after 72 hoursNoNoNA No responseNANANANA28607950
OV_3420Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNASRB assay0.05 MOI80% cell survival after 72 hoursNoNoNA No responseNANANANA28607950
OV_3421Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNASRB assay0.1 MOI80% cell survival after 72 hoursNoNoNA No responseNANANANA28607950
OV_3422Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNASRB assay0.5 MOI50% cell survival after 72 hoursNoNoNA No responseNANANANA28607950
OV_3423Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPYesNoNoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNASRB assay1 MOI30% cell survival after 72 hoursNoNoNA No responseNANANANA28607950
OV_3424Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with gemcitabine (2 × 10⁻² micromolar) after 1 hourNoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNASRB assay0.01 MOI75% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3425Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with gemcitabine (2 × 10⁻² micromolar) after 24 hourNoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNASRB assay0.01 MOI75% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3426Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with gemcitabine 3 × 10⁻² micromolar) after 1 hourNoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNASRB assay0.5 MOI50% of tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3427Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with gemcitabine (3 × 10⁻² micromolar) after 24 hourNoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNASRB assay0.5 MOI75% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3428Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with gemcitabine (1 × 10⁻¹ micromolar) after 1 hourNoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNASRB assay0.1 MOI60% of tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3429Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with gemcitabine (1 × 10⁻¹ micromolar) after 24 hourNoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNASRB assay0.1 MOI55% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3430Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with gemcitabine (7.5 × 10⁻² micromolar) after 1 hourNoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNASRB assay0.1 MOI75% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3431Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with gemcitabine (7.5 × 10⁻² micromolar) after 24 hourNoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNASRB assay0.1 MOI75% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3432Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (1 × 10⁻² micromolar) after 1 hourNoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNASRB assay0.01 MOI25% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3433Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (1 × 10⁻² micromolar) after 24 hourNoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNASRB assay0.01 MOI50% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3434Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (5 × 10⁻³ micromolar) after 1 hourNoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNASRB assay0.5 MOI50% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3435Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (5 × 10⁻³ micromolar) after 24 hourNoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNASRB assay0.5 MOI75% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3436Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (1 × 10⁻² micromolar) after 1 hourNoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNASRB assay0.1 MOI30% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3437Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (1 × 10⁻² micromolar) after 24 hourNoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNASRB assay0.1 MOI50% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3438Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (5 × 10⁻³ micromolar) after 1 hourNoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNASRB assay0.1 MOI50% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3439Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (5 × 10⁻³ micromolar) after 24 hourNoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNASRB assay0.1 MOI60% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3440Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM)NoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNASRB assay0.01 MOI70% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3441Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM)NoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNASRB assay0.03 MOI60% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3442Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM)NoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNASRB assay0.05 MOI52% of the tumor cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3443Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM)NoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNACTB assay0.01 MOI50% cell viability after 72 hoursNoNoNA No responseNANANANA28607950
OV_3444Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM)NoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNACTB assay0.03 MOI40% cell viability after 72 hoursNoNoNA No responseNANANANA28607950
OV_3445Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM)NoATCCHuman pancreatic adenocarcinoma cell lineBxPC-34.0E+4 cells per wellNACTB assay0.05 MOI30% cell viability after 72 hoursNoNoNA No responseNANANANA28607950
OV_3446Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (15 nM)NoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNASRB assay0.5 MOI60% cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3447Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (15 nM)NoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNASRB assay0.75 MOI55% cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3448Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (15 nM)NoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNASRB assay1 MOI55% cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3449Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (15 nM)NoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNACTB assay0.5 MOI50% cell viability after 72 hoursNoNoNA No responseNANANANA28607950
OV_3450Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (15 nM)NoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNACTB assay0.75 MOI45% cell viability after 72 hoursNoNoNA No responseNANANANA28607950
OV_3451Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (15 nM)NoATCCHuman pancreatic adenocarcinoma cell lineMIAPaCa-24.0E+4 cells per wellNACTB assay1 MOI40% cell viability after 72 hoursNoNoNA No responseNANANANA28607950
OV_3452Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM)NoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNASRB assay0.075 MOI60% cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3453Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM)NoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNASRB assay0.1 MOI60% cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3454Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM)NoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNASRB assay0.125 MOI60% cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3455Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM)NoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNACTB assay0.075 MOI45% cell viability after 72 hoursNoNoNA No responseNANANANA28607950
OV_3456Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM)NoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNACTB assay0.1 MOI45% cell viability after 72 hoursNoNoNA No responseNANANANA28607950
OV_3457Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM)NoATCCHuman pancreatic adenocarcinoma cell lineAsPC-15.0E+4 cells per wellNACTB assay0.125 MOI45% cell viability after 72 hoursNoNoNA No responseNANANANA28607950
OV_3458Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM)NoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNASRB assay0.075 MOI75% cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3459Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM)NoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNASRB assay0.1 MOI75% cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3460Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM)NoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNASRB assay0.125 MOI72% cell mass remain after 72 hoursNoNoNA No responseNANANANA28607950
OV_3461Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM)NoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNACTB assay0.075 MOI72% cell viability after 72 hoursNoNoNA No responseNANANANA28607950
OV_3462Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM)NoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNACTB assay0.1 MOI70% cell viability after 72 hoursNoNoNA No responseNANANANA28607950
OV_3463Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of three gene beta-glucouronidase, galactosidase and GFPNoVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM)NoATCCHuman pancreatic adenocarcinoma cell linePANC-14.0E+4 cells per wellNACTB assay0.125 MOI70% cell viability after 72 hoursNoNoNA No responseNANANANA28607950
OV_3741Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell linePANC-15.0E+3 cells per wellNAMTT assay0.0001 MOI100% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3742Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell linePANC-15.0E+3 cells per wellNAMTT assay0.001 MOI100% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3743Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell linePANC-15.0E+3 cells per wellNAMTT assay0.01 MOI80% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3744Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell linePANC-15.0E+3 cells per wellNAMTT assay1 MOI20% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3745Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell linePANC-15.0E+3 cells per wellNAMTT assay2 MOI100% cell killing after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3746Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell linePANC-15.0E+3 cells per wellNAMTT assay3 MOI100% cell killing after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3747Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell lineSW19905.0E+3 cells per wellNAMTT assay0.0001 MOI100% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3748Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell lineSW19905.0E+3 cells per wellNAMTT assay0.001 MOI100% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3749Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell lineSW19905.0E+3 cells per wellNAMTT assay0.01 MOI90% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3750Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell lineSW19905.0E+3 cells per wellNAMTT assay1 MOI10% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3751Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell lineSW19905.0E+3 cells per wellNAMTT assay2 MOI100% cell killing after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3752Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell lineSW19905.0E+3 cells per wellNAMTT assay3 MOI100% cell killing after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3753Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell lineBxPC-35.0E+3 cells per wellNAMTT assay0.0001 MOI100% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3754Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell lineBxPC-35.0E+3 cells per wellNAMTT assay0.001 MOI100% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3755Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell lineBxPC-35.0E+3 cells per wellNAMTT assay0.01 MOI98% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3756Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell lineBxPC-35.0E+3 cells per wellNAMTT assay1 MOI20% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3757Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell lineBxPC-35.0E+3 cells per wellNAMTT assay2 MOI100% cell killing after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3758Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKYesNoNoType culture collection of chinaHuman pancreatic cancer cell lineBxPC-35.0E+3 cells per wellNAMTT assay3 MOI100% cell killing after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3759Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKNoVirus in combination with gemcitabine (1 micromolar)NoType culture collection of chinaHuman pancreatic cancer cell linePANC-15.0E+3 cells per wellNAMTT assay0.1 MOI70% cell viability after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3760Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKNoVirus in combination with gemcitabine (1 micromolar)NoType culture collection of chinaHuman pancreatic cancer cell linePANC-15.0E+3 cells per wellNAMTT assay0.5 MOI50% cell viability after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3761Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKNoVirus in combination with gemcitabine (5 micromolar)NoType culture collection of chinaHuman pancreatic cancer cell linePANC-15.0E+3 cells per wellNAMTT assay0.1 MOI40% cell viability after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3762Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKNoVirus in combination with gemcitabine (5 micromolar)NoType culture collection of chinaHuman pancreatic cancer cell linePANC-15.0E+3 cells per wellNAMTT assay0.5 MOI20% cell viability after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143
OV_3763Vaccinia virusvv-smacDNAPoxviridaeInsertion of smac and gpt gene in TKNoVirus in combination with gemcitabine (1 micromolar)NoType culture collection of chinaHuman pancreatic cancer cell lineSW19905.0E+3 cells per wellNAMTT assay0.1 MOI70% cell viability after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellNANA30365143