Browse By Oncolytic Virus Species Result Page of OvirusTdb
The Total number of records shown on this page is 100. Click on ID to see further detail.
IDOV_3220 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman bone osteosarcoma cell line | Cell line143-B | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.001 MOI | In-vitro result73% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3221 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman bone osteosarcoma cell line | Cell line143-B | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.01 MOI | In-vitro result60% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3222 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman bone osteosarcoma cell line | Cell line143-B | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.1 MOI | In-vitro result55% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3223 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman bone osteosarcoma cell line | Cell line143-B | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration1 MOI | In-vitro result50% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3224 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman bone osteosarcoma cell line | Cell line143-B | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration10 MOI | In-vitro result40% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3249 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman canine osteosarcoma | Cell lineD17 | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.0001 MOI | In-vitro result80% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3250 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman canine osteosarcoma | Cell lineD17 | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.001 MOI | In-vitro result80% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3251 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman canine osteosarcoma | Cell lineD17 | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.01 MOI | In-vitro result75% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3252 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman canine osteosarcoma | Cell lineD17 | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.1 MOI | In-vitro result72% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3253 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman canine osteosarcoma | Cell lineD17 | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration1 MOI | In-vitro result60% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3254 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman canine osteosarcoma | Cell lineD17 | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration10 MOI | In-vitro result55% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3279 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman synovial sarcoma cell line | Cell lineSW982 | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.0001 MOI | In-vitro result80% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3280 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman synovial sarcoma cell line | Cell lineSW982 | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.001 MOI | In-vitro result80% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3281 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman synovial sarcoma cell line | Cell lineSW982 | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.01 MOI | In-vitro result80% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3282 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman synovial sarcoma cell line | Cell lineSW982 | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.1 MOI | In-vitro result75% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3283 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman synovial sarcoma cell line | Cell lineSW982 | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration1 MOI | In-vitro result70% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3284 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman synovial sarcoma cell line | Cell lineSW982 | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration10 MOI | In-vitro result70% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3404 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.001 MOI | In-vitro resultNo cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3405 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.005 MOI | In-vitro resultNo cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3406 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.01 MOI | In-vitro resultNo cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3407 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.05 MOI | In-vitro result35% cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3408 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro result30% cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3409 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro resultNo cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3410 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.25 MOI | In-vitro resultNo cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3411 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.5 MOI | In-vitro resultNo cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3412 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.75 MOI | In-vitro result28% cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3413 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration1 MOI | In-vitro result25% cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3414 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.01 MOI | In-vitro resultNo cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3415 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.05 MOI | In-vitro result80% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3416 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro result75% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3417 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.5 MOI | In-vitro result25% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3418 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration1 MOI | In-vitro result10% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3419 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.01 MOI | In-vitro resultNo cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3420 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.05 MOI | In-vitro result80% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3421 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro result80% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3422 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.5 MOI | In-vitro result50% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3423 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration1 MOI | In-vitro result30% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3424 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (2 × 10â»Â² micromolar) after 1 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.01 MOI | In-vitro result75% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3425 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (2 × 10â»Â² micromolar) after 24 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.01 MOI | In-vitro result75% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3426 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine 3 × 10â»Â² micromolar) after 1 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.5 MOI | In-vitro result50% of tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3427 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (3 × 10â»Â² micromolar) after 24 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.5 MOI | In-vitro result75% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3428 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (1 × 10â»Â¹ micromolar) after 1 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro result60% of tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3429 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (1 × 10â»Â¹ micromolar) after 24 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro result55% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3430 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (7.5 × 10â»Â² micromolar) after 1 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro result75% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3431 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (7.5 × 10â»Â² micromolar) after 24 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro result75% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3432 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (1 × 10â»Â² micromolar) after 1 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.01 MOI | In-vitro result25% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3433 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (1 × 10â»Â² micromolar) after 24 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.01 MOI | In-vitro result50% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3434 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (5 × 10â»Â³ micromolar) after 1 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.5 MOI | In-vitro result50% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3435 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (5 × 10â»Â³ micromolar) after 24 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.5 MOI | In-vitro result75% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3436 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (1 × 10â»Â² micromolar) after 1 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro result30% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3437 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (1 × 10â»Â² micromolar) after 24 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro result50% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3438 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (5 × 10â»Â³ micromolar) after 1 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro result50% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3439 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (5 × 10â»Â³ micromolar) after 24 hour | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro result60% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3440 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.01 MOI | In-vitro result70% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3441 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.03 MOI | In-vitro result60% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3442 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.05 MOI | In-vitro result52% of the tumor cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3443 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration0.01 MOI | In-vitro result50% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3444 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration0.03 MOI | In-vitro result40% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3445 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineBxPC-3 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration0.05 MOI | In-vitro result30% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3446 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (15 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.5 MOI | In-vitro result60% cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3447 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (15 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.75 MOI | In-vitro result55% cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3448 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (15 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration1 MOI | In-vitro result55% cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3449 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (15 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration0.5 MOI | In-vitro result50% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3450 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (15 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration0.75 MOI | In-vitro result45% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3451 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (15 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineMIAPaCa-2 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration1 MOI | In-vitro result40% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3452 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.075 MOI | In-vitro result60% cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3453 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro result60% cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3454 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.125 MOI | In-vitro result60% cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3455 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration0.075 MOI | In-vitro result45% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3456 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration0.1 MOI | In-vitro result45% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3457 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (10 nM)and gemcitabine (100 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell lineAsPC-1 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration0.125 MOI | In-vitro result45% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3458 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.075 MOI | In-vitro result75% cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3459 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.1 MOI | In-vitro result75% cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3460 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssaySRB assay | In-vitro virus concentration0.125 MOI | In-vitro result72% cell mass remain after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3461 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration0.075 MOI | In-vitro result72% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3462 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration0.1 MOI | In-vitro result70% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3463 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of three gene beta-glucouronidase, galactosidase and GFP | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with nab-palcitaxel (2.5 nM)and gemcitabine (37.5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic adenocarcinoma cell line | Cell linePANC-1 | Concentration of cell line4.0E+4 cells per well | In-vitro toxicityNA | AssayCTB assay | In-vitro virus concentration0.125 MOI | In-vitro result70% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28607950 |
IDOV_3741 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.0001 MOI | In-vitro result100% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3742 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.001 MOI | In-vitro result100% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3743 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result80% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3744 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result20% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3745 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result100% cell killing after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3746 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration3 MOI | In-vitro result100% cell killing after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3747 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineSW1990 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.0001 MOI | In-vitro result100% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3748 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineSW1990 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.001 MOI | In-vitro result100% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3749 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineSW1990 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result90% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3750 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineSW1990 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result10% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3751 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineSW1990 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result100% cell killing after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3752 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineSW1990 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration3 MOI | In-vitro result100% cell killing after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3753 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.0001 MOI | In-vitro result100% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3754 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.001 MOI | In-vitro result100% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3755 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result98% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3756 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result20% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3757 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result100% cell killing after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3758 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration3 MOI | In-vitro result100% cell killing after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3759 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (1 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result70% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3760 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (1 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.5 MOI | In-vitro result50% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3761 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (5 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result40% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3762 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (5 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.5 MOI | In-vitro result20% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3763 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (1 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineSW1990 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result70% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |