Detailed description page of Selected OV_ID


OV_3426 details
Primary information
OV_IDOV_3426
Virus Name Vaccinia virus
StrainGLV-1h68
Virus typeDNA
Virus familyPoxviridae
Modification in virus genomeInsertion of three gene beta-glucouronidase, galactosidase and GFP
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with gemcitabine 3 × 10⁻² micromolar) after 1 hour
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman pancreatic adenocarcinoma cell line
Cell lineMIAPaCa-2
Concentration of cell line4
In-vitro toxicityNA
AssaySRB assay
In-vitro virus concentration0.5 MOI
In-vitro result50% of tumor cell mass remain after 72 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID28607950