Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_2006ReovirusReovirus T3DRNAReoviridaeNoneYesNoNoATCCHuman glioma cell lineU373NANAMTT assay5 MOI42% cell survivalNoNoNA No responseNAVirus alone and in combination enhance apoptosisNANA21607667
OV_2008ReovirusReovirus T3DRNAReoviridaeNoneNoReovirus in combination with NDVNoATCCHuman glioma cell lineU373NANAMTT assay5 MOI10% cell survivalNoNoNA No responseNAVirus alone and in combination enhance apoptosisNANA21607667
OV_2009ReovirusReovirus T3DRNAReoviridaeNoneNoReovirus in combination with parovirusNoATCCHuman glioma cell lineU373NANAMTT assay5 MOI12% cell survivalNoNoNA No responseNAVirus alone and in combination enhance apoptosisNANA21607667
OV_2012ReovirusReovirus T3DRNAReoviridaeNoneYesNoNoATCCHuman glioma cell lineU87NANANANANASCID/NOD mice xenograft for U87 cell line1.0E+8 pfuNA Reduction in tumor volume below 40mm after 12 daysIntrtumoralVirus alone and in combination enhance apoptosisNANA21607667
OV_2013ReovirusReovirus T3DRNAReoviridaeNoneNoReovirus in combination with parovirusNoATCCHuman glioma cell lineU87NANANANANASCID/NOD mice xenograft for U87 cell line1.0E+8 pfuNA Reduction in tumor volume below 10mm after 12 daysIntrtumoralVirus alone and in combination enhance apoptosisNANA21607667
OV_2014ReovirusReovirus T3DRNAReoviridaeNoneYesNoNoNAHuman prostate cancer cell linePC-35.0E+3 cells per wellNAMTS assay0.1 MOI70% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2015ReovirusReovirus T3DRNAReoviridaeNoneYesNoNoNAHuman prostate cancer cell linePC-35.0E+3 cells per wellNAMTS assay1 MOI30% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2016ReovirusReovirus T3DRNAReoviridaeNoneYesNoNoNAHuman prostate cancer cell linePC-35.0E+3 cells per wellNAMTS assay10 MOI10% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2017ReovirusReovirus T3DRNAReoviridaeNoneYesNoNoNAHuman prostate cancer cell linePC-35.0E+3 cells per wellNAMTS assay100 MOI100% cell deathNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2018ReovirusReovirus T3DRNAReoviridaeNoneYesNoNoNAHuman prostate cancer cell lineLNCaP7.5E+3 cells per wellNAMTS assay0.1 MOI90% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2019ReovirusReovirus T3DRNAReoviridaeNoneYesNoNoNAHuman prostate cancer cell lineLNCaP7.5E+3 cells per wellNAMTS assay1 MOI60% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2020ReovirusReovirus T3DRNAReoviridaeNoneYesNoNoNAHuman prostate cancer cell lineLNCaP7.5E+3 cells per wellNAMTS assay10 MOI20% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2021ReovirusReovirus T3DRNAReoviridaeNoneYesNoNoNAHuman prostate cancer cell lineLNCaP7.5E+3 cells per wellNAMTS assay100 MOI100% cell deathNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2022ReovirusReovirus T3DRNAReoviridaeNoneYesNoNoNAHuman prostate cancer cell lineDu1457.5E+3 cells per wellNAMTS assay0.1 MOI100% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2023ReovirusReovirus T3DRNAReoviridaeNoneYesNoNoNAHuman prostate cancer cell lineDu1457.5E+3 cells per wellNAMTS assay1 MOI100% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2024ReovirusReovirus T3DRNAReoviridaeNoneYesNoNoNAHuman prostate cancer cell lineDu1457.5E+3 cells per wellNAMTS assay10 MOI70% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2025ReovirusReovirus T3DRNAReoviridaeNoneYesNoNoNAHuman prostate cancer cell lineDu1457.5E+3 cells per wellNAMTS assay100 MOI10% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2026ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (7.5 nM)NoNAHuman prostate cancer cell linePC-35.0E+3 cells per wellNAMTS assay0.125 MOI80% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2027ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (15 nM)NoNAHuman prostate cancer cell linePC-35.0E+3 cells per wellNAMTS assay0.25 MOI70% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2028ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (30 nM)NoNAHuman prostate cancer cell linePC-35.0E+3 cells per wellNAMTS assay0.5 MOI60% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2029ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (60 nM)NoNAHuman prostate cancer cell linePC-35.0E+3 cells per wellNAMTS assay1 MOI50% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2030ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (120 nM)NoNAHuman prostate cancer cell linePC-35.0E+3 cells per wellNAMTS assay2 MOI40% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2031ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (7.5 nM)NoNAHuman prostate cancer cell lineLNCaP7.5E+3 cells per wellNAMTS assay0.125 MOI70% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2032ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (15 nM)NoNAHuman prostate cancer cell lineLNCaP7.5E+3 cells per wellNAMTS assay0.25 MOI70% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2033ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (30 nM)NoNAHuman prostate cancer cell lineLNCaP7.5E+3 cells per wellNAMTS assay0.5 MOI60% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2034ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (60 nM)NoNAHuman prostate cancer cell lineLNCaP7.5E+3 cells per wellNAMTS assay1 MOI50% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2035ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (120 nM)NoNAHuman prostate cancer cell lineLNCaP7.5E+3 cells per wellNAMTS assay2 MOI40% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2036ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (120 nM)NoNAHuman prostate cancer cell lineDu1457.5E+3 cells per wellNAMTS assay0.125 MOI60% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2037ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (120 nM)NoNAHuman prostate cancer cell lineDu1457.5E+3 cells per wellNAMTS assay0.25 MOI45% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2038ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (120 nM)NoNAHuman prostate cancer cell lineDu1457.5E+3 cells per wellNAMTS assay0.5 MOI30% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2039ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (120 nM)NoNAHuman prostate cancer cell lineDu1457.5E+3 cells per wellNAMTS assay1 MOI20% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2040ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (120 nM)NoNAHuman prostate cancer cell lineDu1457.5E+3 cells per wellNAMTS assay2 MOI20% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2041ReovirusReovirus T3DRNAReoviridaeNoneNovirus in combination with Docetaxel (7.5)NoNAHuman prostate cancer cell lineDu1457.5E+3 cells per wellMTS assay2.15 MOI70% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2042ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (15 nM)NoNAHuman prostate cancer cell lineDu1457.5E+3 cells per wellMTS assay4.3 MOI50% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2043ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (30 nM)NoNAHuman prostate cancer cell lineDu1457.5E+3 cells per wellMTS assay8.6 MOI30% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2044ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (60 nM)NoNAHuman prostate cancer cell lineDu1457.5E+3 cells per wellMTS assay17.2 MOI10% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2045ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (120 nM)NoNAHuman prostate cancer cell lineDu1457.5E+3 cells per wellMTS assay34.4 MOI10% cell survivalNoNoNA No responseNAVirus cause increase in apoptosisNANA21645351
OV_2046ReovirusReovirus T3DRNAReoviridaeNoneNoVirus strain in combination with Docetaxel (5 mg/kg)NoNAHuman prostate cancer cell lineLNCaPNANANANANAMice injected with PC3 cell line1.0E+8 pfuNA Reduction in tumor volume after day 15IntratumoralVirus cause increase in apoptosisNANA21645351
OV_2977Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman neck and squamous carcinoma cell lineSCC-97.68E+3 cells per wellNAAlamar blue assay2.4 × 10⁸ pfu33.2 +/- 9.9% cell viable after 96 hoursNoNoNA No responseNANANANA25890191
OV_2978Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman neck and squamous carcinoma cell lineSCC-257.68E+3 cells per wellNAAlamar blue assay2.4 × 10⁸ pfu54.6 +/- 21.5% cell viable after 96 hoursNoNoNA No responseNANANANA25890191
OV_2979Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman neck and squamous carcinoma cell lineUM-SCC-387.68E+3 cells per wellNAAlamar blue assay2.4 × 10⁸ pfu83.9 +/- 16.3% cell viable after 96 hoursNoNoNA No responseNANANANA25890191
OV_2980Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman neck and squamous carcinoma cell lineUM-SCC-477.68E+3 cells per wellNAAlamar blue assay2.4 × 10⁸ pfu97.2 +/- 4.7% cell viable after 96 hoursNoNoNA No responseNANANANA25890191
OV_2981Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman neck and squamous carcinoma cell lineUM-SCC-1047.68E+3 cells per wellNAAlamar blue assay2.4 × 10⁸ pfu82.3 +/- 6.5% cell viable after 96 hoursNoNoNA No responseNANANANA25890191
OV_3183Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman edwig sarcoma cell lineRD-ES90% confluenceNACrystal violet staining and absorbance at 595 nm0.0001 MOI75% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3184Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman edwig sarcoma cell lineRD-ES90% confluenceNACrystal violet staining and absorbance at 595 nm0.001 MOI50% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3185Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman edwig sarcoma cell lineRD-ES90% confluenceNACrystal violet staining and absorbance at 595 nm0.01 MOI50% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3186Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman edwig sarcoma cell lineRD-ES90% confluenceNACrystal violet staining and absorbance at 595 nm0.1 MOI40% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3187Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman edwig sarcoma cell lineRD-ES90% confluenceNACrystal violet staining and absorbance at 595 nm1 MOI40% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3188Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman edwig sarcoma cell lineRD-ES90% confluenceNACrystal violet staining and absorbance at 595 nm10 MOI25% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3213Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman bone osteosarcoma cell line143-B90% confluenceNACrystal violet staining and absorbance at 595 nm0.0001 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3214Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman bone osteosarcoma cell line143-B90% confluenceNACrystal violet staining and absorbance at 595 nm0.001 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3215Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman bone osteosarcoma cell line143-B90% confluenceNACrystal violet staining and absorbance at 595 nm0.01 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3216Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman bone osteosarcoma cell line143-B90% confluenceNACrystal violet staining and absorbance at 595 nm0.1 MOI75% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3217Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman bone osteosarcoma cell line143-B90% confluenceNACrystal violet staining and absorbance at 595 nm1 MOI75% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3218Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman bone osteosarcoma cell line143-B90% confluenceNACrystal violet staining and absorbance at 595 nm10 MOI75% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3243Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman canine osteosarcomaD1790% confluenceNACrystal violet staining and absorbance at 595 nm0.0001 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3244Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman canine osteosarcomaD1790% confluenceNACrystal violet staining and absorbance at 595 nm0.001 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3245Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman canine osteosarcomaD1790% confluenceNACrystal violet staining and absorbance at 595 nm0.01 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3246Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman canine osteosarcomaD1790% confluenceNACrystal violet staining and absorbance at 595 nm0.1 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3247Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman canine osteosarcomaD1790% confluenceNACrystal violet staining and absorbance at 595 nm1 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3248Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman canine osteosarcomaD1790% confluenceNACrystal violet staining and absorbance at 595 nm10 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3273Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman synovial sarcoma cell lineSW98290% confluenceNACrystal violet staining and absorbance at 595 nm0.0001 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3274Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman synovial sarcoma cell lineSW98290% confluenceNACrystal violet staining and absorbance at 595 nm0.001 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3275Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman synovial sarcoma cell lineSW98290% confluenceNACrystal violet staining and absorbance at 595 nm0.01 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3276Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman synovial sarcoma cell lineSW98290% confluenceNACrystal violet staining and absorbance at 595 nm0.1 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3277Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman synovial sarcoma cell lineSW98290% confluenceNACrystal violet staining and absorbance at 595 nm1 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3278Reoviruswild typeRNAReoviridaeNoneYesNoNoATCCHuman synovial sarcoma cell lineSW98290% confluenceNACrystal violet staining and absorbance at 595 nm10 MOI80% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3314ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay10 pfu70% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3315ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay100 pfu50% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3316ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay1000 pfu30% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3317ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay10 pfu80% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3318ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay100 pfu30% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3319ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay1000 pfu10% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3320ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay10 pfu20% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3321ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay100 pfu5% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3322ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay1000 pfu100% cell killing after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3323ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay10 pfu80% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3324ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay100 pfu70% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3325ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay1000 pfu70% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3326ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay10 pfu100% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3327ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay100 pfu80% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3328ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay1000 pfu70% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3329ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay10 pfu100% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3330ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay100 pfu50% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3331ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH6611.0E+4 cells per wellNACell-titer-glo assay1000 pfu50% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3332ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay10 pfu100% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3333ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay100 pfu70% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3334ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay1000 pfu60% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3335ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay10 pfu80% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3336ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay100 pfu30% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3337ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay1000 pfu20% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3338ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay10 pfu70% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3339ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay100 pfu20% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3340ReovirusRecombinant reovirus T1LRNAReoviridaeMutant in L1 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay1000 pfu100% cell killing after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3341ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay10 pfu100% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3342ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay100 pfu90% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3343ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay1000 pfu80% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3344ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay10 pfu100% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3345ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay100 pfu80% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298
OV_3346ReovirusRecombinant reovirus T3LRNAReoviridaeSubstitution mutant in T3 geneYesNoNoATCCHuman lung cancer cell lineH-12991.0E+4 cells per wellNACell-titer-glo assay1000 pfu70% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA28587298