Detailed description page of Selected OV_ID


OV_3345 details
Primary information
OV_IDOV_3345
Virus Name Reovirus
StrainRecombinant reovirus T3L
Virus typeRNA
Virus familyReoviridae
Modification in virus genomeSubstitution mutant in T3 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman lung cancer cell line
Cell lineH-1299
Concentration of cell line1
In-vitro toxicityNA
AssayCell-titer-glo assay
In-vitro virus concentration100 pfu
In-vitro result80% cell viability after 48 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis
Immunogenic effectNA
Clinical trialNA
PMID28587298