Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_1162Herpes simplex virusFusOn-H2 strainDNAHerpesviridaeDouble fusogenic expressing EGFP and GALV.fus proteinYesNoNoATCCRenal cell carcinoma cell lineACHN1.5E+3 cells per wellNATrypan blue staining0.1 pfu/cell50% cell survival after 24 hoursNoNoNA No responseNANANANA17487379
OV_1163Herpes simplex virusBaco-1DNAHerpesviridaeNon- fusogenic ligated with EGFP proteinYesNoNoATCCRenal cell carcinoma cell lineA4891.5E+3 cells per wellNATrypan blue staining0.1 pfu/cell55% cell survival after 24 hoursNoNoNA No responseNANANANA17487379
OV_1164Herpes simplex virusFusOn-H2 strainDNAHerpesviridaeDouble fusogenic expressing EGFP and GALV.fus proteinYesNoNoATCCRenal cell carcinoma cell lineACHN1.5E+3 cells per wellNATrypan blue staining0.1 pfu/cell5% cell survival after 48 hoursNoNoNA No responseNANANANA17487379
OV_1165Herpes simplex virusBaco-1DNAHerpesviridaeNon- fusogenic ligated with EGFP proteinYesNoNoATCCRenal cell carcinoma cell lineA4891.5E+3 cells per wellNATrypan blue staining0.1 pfu/cell20% cell survival after 48 hoursNoNoNA No responseNANANANA17487379
OV_1166Herpes simplex virusFusOn-H2 strainDNAHerpesviridaeDouble fusogenic expressing EGFP and GALV.fus proteinYesNoNoATCCRenal cell carcinoma cell lineACHN1.5E+3 cells per wellNATrypan blue staining0.01pfu/cell55% cell survival after 24 hoursNoNoNA No responseNANANANA17487379
OV_1167Herpes simplex virusBaco-1DNAHerpesviridaeNon- fusogenic ligated with EGFP proteinYesNoNoATCCRenal cell carcinoma cell lineA4891.5E+3 cells per wellNATrypan blue staining0.01pfu/cell57% cell survival after 24 hoursNoNoNA No responseNANANANA17487379
OV_1168Herpes simplex virusFusOn-H2 strainDNAHerpesviridaeDouble fusogenic expressing EGFP and GALV.fus proteinYesNoNoATCCRenal cell carcinoma cell lineACHN1.5E+3 cells per wellNATrypan blue staining0.01pfu/cell10% cell survival after 48 hoursNoNoNA No responseNANANANA17487379
OV_1169Herpes simplex virusBaco-1DNAHerpesviridaeNon- fusogenic ligated with EGFP proteinYesNoNoATCCRenal cell carcinoma cell lineA4891.5E+3 cells per wellNATrypan blue staining0.01pfu/cell30% cell survival after 48 hoursNoNoNA No responseNANANANA17487379
OV_1264Herpes simplex virusHSV-HF10DNAHerpesviridaeAttenuated strain of HSVYesNoNoTohuku University, JapanMurine melanoma cell lineM32.0E+5 cells per wellNATrypan Blue exclusion assay3 MOI20% cell viablity observed after 24 hoursNoNoNA No responseNANANANA18226503
OV_1265Herpes simplex virusHSV-HF10DNAHerpesviridaeAttenuated strain of HSVYesNoNoTohuku University, JapanMurine melanoma cell lineM32.0E+5 cells per wellNATrypan Blue exclusion assay0.3 MOI25% cell viablity after 24 hoursNoNoNA No responseNANANANA18226503
OV_1266Herpes simplex virusHSV-HF10DNAHerpesviridaeAttenuated strain of HSVYesNoNoTohuku University, JapanMurine melanoma cell lineM32.0E+5 cells per wellNATrypan Blue exclusion assay0.03 MOI40% cell viablity after 24 hoursNoNoNA No responseNANANANA18226503
OV_1267Herpes simplex virusHSV-HF10DNAHerpesviridaeAttenuated strain of HSVYesNoNoTohuku University, JapanMurine melanoma cell lineM32.0E+5 cells per wellNATrypan Blue exclusion assay0.003 MOI90% cell viability after 24 hoursNoNoNA No responseNANANANA18226503
OV_1268Herpes simplex virusHSV-HF10DNAHerpesviridaeAttenuated strain of HSVYesNoNoTohuku University, JapanMurine melanoma cell lineM32.0E+5 cells per wellNATrypan Blue exclusion assay3 MOINo cell viability after 48 hoursNoNoNA No responseNANANANA18226503
OV_1269Herpes simplex virusHSV-HF10DNAHerpesviridaeAttenuated strain of HSVYesNoNoTohuku University, JapanMurine melanoma cell lineM32.0E+5 cells per wellNATrypan Blue exclusion assay0.3 MOINo cell viability after 48 hoursNoNoNA No responseNANANANA18226503
OV_1270Herpes simplex virusHSV-HF10DNAHerpesviridaeAttenuated strain of HSVYesNoNoTohuku University, JapanMurine melanoma cell lineM32.0E+5 cells per wellNATrypan Blue exclusion assay0.03 MOI10% cell viabilty after 48 hoursNoNoNA No responseNANANANA18226503
OV_1271Herpes simplex virusHSV-HF10DNAHerpesviridaeAttenuated strain of HSVYesNoNoTohuku University, JapanMurine melanoma cell lineM32.0E+5 cells per wellNATrypan Blue exclusion assay0.003 MOI40% cell viability after 48 hoursNoNoNA No responseNANANANA18226503
OV_1272Herpes simplex virusHSV-HF10DNAHerpesviridaeAttenuated strain of HSVYesNoNoTohuku University, JapanMurine melanoma cell lineM32.0E+5 cells per wellNATrypan Blue exclusion assay3 MOINo cell viability after 72 hoursNoNoNA No responseNANANANA18226503
OV_1273Herpes simplex virusHSV-HF10DNAHerpesviridaeAttenuated strain of HSVYesNoNoTohuku University, JapanMurine melanoma cell lineM32.0E+5 cells per wellNATrypan Blue exclusion assay0.3 MOINo cell viability after 72 hoursNoNoNA No responseNANANANA18226503
OV_1274Herpes simplex virusHSV-HF10DNAHerpesviridaeAttenuated strain of HSVYesNoNoTohuku University, JapanMurine melanoma cell lineM32.0E+5 cells per wellNATrypan Blue exclusion assay0.03 MOINo cell viability after 72 hoursNoNoNA No responseNANANANA18226503
OV_1275Herpes simplex virusHSV-HF10DNAHerpesviridaeAttenuated strain of HSVYesNoNoTohuku University, JapanMurine melanoma cell lineM32.0E+5 cells per wellNATrypan Blue exclusion assay0.003 MOI7.4% cell viability after 72 hoursNoNoNA No responseNANANANA18226503
OV_1276Herpes simplex virusHSV-HF10DNAHerpesviridaeAttenuated strain of HSVYesNoNoNANANANANANANANADBA/2 mice model isograft for M3 cell line1.0E+6 pfuNA All mice survivedIntraperoronealNAInduction of HSV antigen positive cellsNA18226503
OV_1277Herpes simplex virusHSV-HF10DNAHerpesviridaeAttenuated strain of HSVYesNoNoNANANANANANANANADBA/2 mice model isograft for M3 cell line1.0E+7 pfuNA Significant reduction in tumor size on day 18 and complete reduction of tumor size in some miceSubcutaneousNAInduction of HSV antigen positive cellsNA18226503
OV_1649Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineLN22NANACrystal violet staining0.05 MOI90% cell survival after 3 daysNoNoNA No responseNANANANA19844198
OV_1650Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineLN22NANACrystal violet staining0.1 MOI90% cell survival after 3 daysNoNoNA No responseNANANANA19844198
OV_1651Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineLN22NANACrystal violet staining0.5 MOI30% cell survival after 3 daysNoNoNA No responseNANANANA19844198
OV_1652Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineLN22NANACrystal violet staining1 MOI20% cell survival after 3 daysNoNoNA No responseNANANANA19844198
OV_1653Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineU87deltaEGFRNANACrystal violet staining0.05 MOI70% cell survival after 3 daysNoNoNA No responseNANANANA19844198
OV_1654Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineU87deltaEGFRNANACrystal violet staining0.1 MOI60% cell survival after 3 daysNoNoNA No responseNANANANA19844198
OV_1655Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineU87deltaEGFRNANACrystal violet staining0.5 MOI10% cell survival after 3 daysNoNoNA No responseNANANANA19844198
OV_1656Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineU87deltaEGFRNANACrystal violet staining1 MOI100% cell death after 3 daysNoNoNA No responseNANANANA19844198
OV_1657Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineGlideltaEGFR-H2B-RFPNANACrystal violet staining0.05 MOI70% cell survival after day 3NoNoNA No responseNANANANA19844198
OV_1658Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineGlideltaEGFR-H2B-RFPNANACrystal violet staining0.1 MOI40% cell survival after day 3NoNoNA No responseNANANANA19844198
OV_1659Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineGlideltaEGFR-H2B-RFPNANACrystal violet staining0.5 MOI100% cell death after 3 daysNoNoNA No responseNANANANA19844198
OV_1660Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineGlideltaEGFR-H2B-RFPNANACrystal violet staining1 MOI100% cell death after 3 daysNoNoNA No responseNANANANA19844198
OV_1661Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineU343NANACrystal violet staining0.05 MOI100% cell survival after day 3NoNoNA No responseNANANANA19844198
OV_1662Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineU343NANACrystal violet staining0.1 MOI90% cell survival after 3 daysNoNoNA No responseNANANANA19844198
OV_1663Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineU343NANACrystal violet staining0.5 MOI40% cell survival after day 3NoNoNA No responseNANANANA19844198
OV_1664Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneATCCHuman glioma cell lineU343NANACrystal violet staining1 MOI40% cell survival after day 3NoNoNA No responseNANANANA19844198
OV_1665Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneNANANANANANANANAAthymic nude mice, injected with U87deltaEGFR cell line1.0E+5 pfuNA Significant increase in median survival time of miceIntracranialNANANA19844198
OV_1666Herpes simplex virusHSV-1DNAHerpesviridaeNoneYesNoVirus expressing vstat120 geneNANANANANANANANAAthymic nude mice, injected with GlideltaEGFR-H2B-RFP cell line1.5E+6 cellsNA Significant reduction in tumor volume and increase in median survival time of miceSubcutaneouslyNANANA19844198
OV_1842Herpes simplex virusNV1023DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.01 MOI100% cell survival after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1843Herpes simplex virusNV1024DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.01 MOI100% cell survival after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1844Herpes simplex virusNV1025DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.01 MOI80% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1845Herpes simplex virusNV1026DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.01 MOI70% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1846Herpes simplex virusNV1027DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.1 MOI90% cell survival after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1847Herpes simplex virusNV1028DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.1 MOI90% cell survival after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1848Herpes simplex virusNV1029DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.1 MOI80% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1849Herpes simplex virusNV1030DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.1 MOI60% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1850Herpes simplex virusNV1031DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay1 MOI70% cell survival after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1851Herpes simplex virusNV1032DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay1 MOI65% cell survival after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1852Herpes simplex virusNV1033DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay1 MOI50% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1853Herpes simplex virusNV1034DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay1 MOI20% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1854Herpes simplex virusNV1035DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.1 MOINo cell killing after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1855Herpes simplex virusNV1036DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.1 MOINo cell killing after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1856Herpes simplex virusNV1037DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.1 MOINo cell killing after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1857Herpes simplex virusNV1038DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.1 MOINo cell killing after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1858Herpes simplex virusNV1039DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.2 MOINo cell killing after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1859Herpes simplex virusNV1040DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.2 MOINo cell killing after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1860Herpes simplex virusNV1041DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.2 MOI98% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1861Herpes simplex virusNV1042DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.2 MOINo cell killing after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1862Herpes simplex virusNV1043DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.4 MOINo cell killing after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1863Herpes simplex virusNV1044DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.4 MOINo cell killing after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1864Herpes simplex virusNV1045DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.4 MOINo cell killing after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1865Herpes simplex virusNV1046DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.4 MOINo cell killing after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1866Herpes simplex virusNV1047DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.8 MOINo cell killing after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1867Herpes simplex virusNV1048DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.8 MOINo cell killing after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1868Herpes simplex virusNV1049DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.8 MOINo cell killing after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1869Herpes simplex virusNV1050DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.8 MOI90% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1870Herpes simplex virusNV1051DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay1.6 MOINo cell killing after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1871Herpes simplex virusNV1052DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay1.6 MOI90% cell survival after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1872Herpes simplex virusNV1053DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay1.6 MOI90% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1873Herpes simplex virusNV1054DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay1.6 MOI80% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1874Herpes simplex virusNV1055DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay3.2 MOINo cell killing after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1875Herpes simplex virusNV1056DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay3.2 MOI90% cell survival after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1876Herpes simplex virusNV1057DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay3.2 MOI80% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1877Herpes simplex virusNV1058DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay3.2 MOI80% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1878Herpes simplex virusNV1059DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.012 MOI90% cell survival after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1879Herpes simplex virusNV1060DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.012 MOI90% cell survival after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1880Herpes simplex virusNV1061DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.012 MOI90% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1881Herpes simplex virusNV1062DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.012 MOI80% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1882Herpes simplex virusNV1063DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.037 MOI80% cell survival after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1883Herpes simplex virusNV1064DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.037 MOI80% cell survival after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1884Herpes simplex virusNV1065DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.037 MOI80% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1885Herpes simplex virusNV1066DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.037 MOI78% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1886Herpes simplex virusNV1067DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.11 MOI90% cell survival after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1887Herpes simplex virusNV1068DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.11 MOI90% cell survival after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1888Herpes simplex virusNV1069DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.11 MOI80% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1889Herpes simplex virusNV1070DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.11 MOI60% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1890Herpes simplex virusNV1071DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.33 MOI60% cell survival after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1891Herpes simplex virusNV1072DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.33 MOI80% cell survival after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1892Herpes simplex virusNV1073DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.33 MOI65% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1893Herpes simplex virusNV1074DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay0.33 MOI60% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1894Herpes simplex virusNV1075DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay1 MOI60% cell survival after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1895Herpes simplex virusNV1076DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay1 MOI60% cell survival after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1896Herpes simplex virusNV1077DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay1 MOI40% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1897Herpes simplex virusNV1078DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay1 MOI30% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1898Herpes simplex virusNV1079DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay3 MOI60% cell survival after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1899Herpes simplex virusNV1080DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay3 MOI50% cell survival after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1900Herpes simplex virusNV1081DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay3 MOI30% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1901Herpes simplex virusNV1082DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell linePANC-12.0E+4 cells per wellNALDH release assay3 MOI20% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009