Detailed description page of Selected OV_ID


OV_1665 details
Primary information
OV_IDOV_1665
Virus Name Herpes simplex virus
StrainHSV-1
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeVirus expressing vstat120 gene
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismAthymic nude mice, injected with U87deltaEGFR cell line
In-vivo virus concentration10⁵ pfu
In-vivo toxicityNA
In-vivo resultSignificant increase in median survival time of mice
Mode of deliveryIntracranial
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID19844198