Browse By Oncolytic Virus Species Result Page of OvirusTdb
The Total number of records shown on this page is 100. Click on ID to see further detail.
IDOV_2470 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result40% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2471 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result30% cell survival after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2472 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2473 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result90% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2474 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result50% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2475 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result40% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2476 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result30% cell survival after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2477 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1650 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2478 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1650 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result60% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2479 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1650 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result50% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2480 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1650 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result45% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2481 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1650 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell death after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2482 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast cancer cell line | Cell lineMDA-MB-231 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result90% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2483 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast cancer cell line | Cell lineMDA-MB-231 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result90% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2484 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast cancer cell line | Cell lineMDA-MB-231 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result90% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2485 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast cancer cell line | Cell lineMDA-MB-231 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result90% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2486 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman thyroid cancer cell line | Cell line8505c | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2487 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman thyroid cancer cell line | Cell line8505c | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result70% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2488 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman thyroid cancer cell line | Cell line8505c | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result30% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2489 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman thyroid cancer cell line | Cell line8505c | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result20% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2490 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result80% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2491 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result60% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2492 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result20% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2493 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result15% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2494 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell death after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2495 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2496 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result30% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2497 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result95% cell killing after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2498 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell killing after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2499 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2500 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result70% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2501 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result40% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2502 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result30% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2503 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result15% cell survival after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2504 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result50% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2505 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result20% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2506 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell death after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2507 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell death after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2508 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell death after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2509 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result50% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2510 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result20% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2511 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell death after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2512 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell death after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2513 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell death after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2514 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1650 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2515 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1650 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result10% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2516 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1650 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell death after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2517 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1650 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell death after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2518 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast cancer cell line | Cell lineMDA-MB-231 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result70% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2519 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast cancer cell line | Cell lineMDA-MB-231 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result10% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2520 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast cancer cell line | Cell lineMDA-MB-231 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result10% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2521 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast cancer cell line | Cell lineMDA-MB-231 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result10% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2522 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman thyroid cancer cell line | Cell line8505c | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result90% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2523 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman thyroid cancer cell line | Cell line8505c | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result20% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2524 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman thyroid cancer cell line | Cell line8505c | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell death after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2525 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman thyroid cancer cell line | Cell line8505c | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell death after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2526 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd:athymic nude mice xenografted for PANC-1 cell line(2.0E+6 cells) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultDecrease in tumor volume below 2 after 34 days | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2527 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd:athymic nude mice xenografted for PANC-1 cell line(2.0E+6 cells) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultDecrease in tumor volume below 2 after 34 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2813 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHT-29 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2814 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHT-29 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2815 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHT-29 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result20% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2816 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT15 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2817 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT15 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2818 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT15 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2819 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-116 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2820 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-116 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result20% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2821 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-116 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result20% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2822 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW620 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2823 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW620 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result90% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2824 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW620 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2825 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineColo-205 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2826 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineColo-205 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result60% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2827 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineColo-205 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result30% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2828 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHT-29 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result80% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2829 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHT-29 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result25% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2830 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHT-29 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result100% cell death after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2831 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT15 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result80% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2832 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT15 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result60% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2833 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT15 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result60% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2834 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-116 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result60% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2835 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-116 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result40% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2836 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-116 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result100% cell death after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2837 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW620 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result80% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2838 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW620 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result40% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2839 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW620 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result100% cell death after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2840 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineColo-205 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result50% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2841 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineColo-205 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result10% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2842 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineColo-205 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result100% cell death after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3 | Clinical trialNA | PMID23531320 |
IDOV_2843 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-116 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd:athymic nude mice xenograft for HCT-116 (5.0E+6 cells) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultSignificant reduction in tumor volume after 42 days | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23531320 |
IDOV_2867 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineOsteosarcoma cell line | Cell line143-B | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result80% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2868 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineOsteosarcoma cell line | Cell line143-B | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result70% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2869 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineOsteosarcoma cell line | Cell line143-B | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result50% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2870 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineOsteosarcoma cell line | Cell line143-B | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result40% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2871 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineOsteosarcoma cell line | Cell lineORD | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result80% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2872 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineOsteosarcoma cell line | Cell lineORD | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2873 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineOsteosarcoma cell line | Cell lineORD | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result30% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2874 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineOsteosarcoma cell line | Cell lineORD | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2875 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineOsteosarcoma cell line | Cell lineHOS | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result30% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2876 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineOsteosarcoma cell line | Cell lineHOS | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result20% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2877 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineOsteosarcoma cell line | Cell lineHOS | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result10% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |