Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_2470Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman squamous cell lineSCC-253.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI40% cell survival after day 7NoNoNA No responseNANANANA22258815
OV_2471Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman squamous cell lineSCC-253.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI30% cell survival after day 9NoNoNA No responseNANANANA22258815
OV_2472Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman mesothelia cell lineMSTO-2113.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI100% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2473Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman mesothelia cell lineMSTO-2113.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI90% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2474Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman mesothelia cell lineMSTO-2113.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI50% cell survival after day 5NoNoNA No responseNANANANA22258815
OV_2475Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman mesothelia cell lineMSTO-2113.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI40% cell survival after day 7NoNoNA No responseNANANANA22258815
OV_2476Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman mesothelia cell lineMSTO-2113.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI30% cell survival after day 9NoNoNA No responseNANANANA22258815
OV_2477Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman lung cancer cell lineH16503.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI100% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2478Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman lung cancer cell lineH16503.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI60% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2479Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman lung cancer cell lineH16503.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI50% cell survival after day 5NoNoNA No responseNANANANA22258815
OV_2480Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman lung cancer cell lineH16503.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI45% cell survival after day 7NoNoNA No responseNANANANA22258815
OV_2481Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman lung cancer cell lineH16503.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI100% cell death after day 9NoNoNA No responseNANANANA22258815
OV_2482Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI90% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2483Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI90% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2484Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI90% cell survival after day 5NoNoNA No responseNANANANA22258815
OV_2485Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI90% cell survival after day 7NoNoNA No responseNANANANA22258815
OV_2486Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI100% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2487Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI70% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2488Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI30% cell survival after day 5NoNoNA No responseNANANANA22258815
OV_2489Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI20% cell survival after day 7NoNoNA No responseNANANANA22258815
OV_2490Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman colorectal cancer cell lineHCT-83.0E+4 cells per wellNALDH release and spectrophometer1 MOI80% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2491Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman colorectal cancer cell lineHCT-83.0E+4 cells per wellNALDH release and spectrophometer1 MOI60% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2492Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman colorectal cancer cell lineHCT-83.0E+4 cells per wellNALDH release and spectrophometer1 MOI20% cell survival after day 5NoNoNA No responseNANANANA22258815
OV_2493Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman colorectal cancer cell lineHCT-83.0E+4 cells per wellNALDH release and spectrophometer1 MOI15% cell survival after day 7NoNoNA No responseNANANANA22258815
OV_2494Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman colorectal cancer cell lineHCT-83.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell death after day 9NoNoNA No responseNANANANA22258815
OV_2495Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman pancreatic cancer cell linePANC-13.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2496Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman pancreatic cancer cell linePANC-13.0E+4 cells per wellNALDH release and spectrophometer1 MOI30% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2497Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman pancreatic cancer cell linePANC-13.0E+4 cells per wellNALDH release and spectrophometer1 MOI95% cell killing after day 5NoNoNA No responseNANANANA22258815
OV_2498Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman pancreatic cancer cell linePANC-13.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell killing after day 5NoNoNA No responseNANANANA22258815
OV_2499Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman gastric cancer cell lineMKN-453.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2500Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman gastric cancer cell lineMKN-453.0E+4 cells per wellNALDH release and spectrophometer1 MOI70% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2501Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman gastric cancer cell lineMKN-453.0E+4 cells per wellNALDH release and spectrophometer1 MOI40% cell survival after day 5NoNoNA No responseNANANANA22258815
OV_2502Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman gastric cancer cell lineMKN-453.0E+4 cells per wellNALDH release and spectrophometer1 MOI30% cell survival after day 7NoNoNA No responseNANANANA22258815
OV_2503Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman gastric cancer cell lineMKN-453.0E+4 cells per wellNALDH release and spectrophometer1 MOI15% cell survival after day 9NoNoNA No responseNANANANA22258815
OV_2504Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman squamous cell lineSCC-253.0E+4 cells per wellNALDH release and spectrophometer1 MOI50% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2505Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman squamous cell lineSCC-253.0E+4 cells per wellNALDH release and spectrophometer1 MOI20% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2506Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman squamous cell lineSCC-253.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell death after day 5NoNoNA No responseNANANANA22258815
OV_2507Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman squamous cell lineSCC-253.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell death after day 7NoNoNA No responseNANANANA22258815
OV_2508Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman squamous cell lineSCC-253.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell death after day 9NoNoNA No responseNANANANA22258815
OV_2509Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman mesothelia cell lineMSTO-2113.0E+4 cells per wellNALDH release and spectrophometer1 MOI50% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2510Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman mesothelia cell lineMSTO-2113.0E+4 cells per wellNALDH release and spectrophometer1 MOI20% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2511Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman mesothelia cell lineMSTO-2113.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell death after day 5NoNoNA No responseNANANANA22258815
OV_2512Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman mesothelia cell lineMSTO-2113.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell death after day 7NoNoNA No responseNANANANA22258815
OV_2513Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman mesothelia cell lineMSTO-2113.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell death after day 9NoNoNA No responseNANANANA22258815
OV_2514Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman lung cancer cell lineH16503.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2515Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman lung cancer cell lineH16503.0E+4 cells per wellNALDH release and spectrophometer1 MOI10% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2516Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman lung cancer cell lineH16503.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell death after day 5NoNoNA No responseNANANANA22258815
OV_2517Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman lung cancer cell lineH16503.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell death after day 7NoNoNA No responseNANANANA22258815
OV_2518Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer1 MOI70% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2519Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer1 MOI10% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2520Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer1 MOI10% cell survival after day 5NoNoNA No responseNANANANA22258815
OV_2521Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer1 MOI10% cell survival after day 7NoNoNA No responseNANANANA22258815
OV_2522Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer1 MOI90% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2523Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer1 MOI20% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2524Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell death after day 5NoNoNA No responseNANANANA22258815
OV_2525Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell death after day 7NoNoNA No responseNANANANA22258815
OV_2526Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman pancreatic cancer cell linePANC-1NANANANANAHsd:athymic nude mice xenografted for PANC-1 cell line(2.0E+6 cells)2.0E+6 pfuNA Decrease in tumor volume below 2 after 34 daysIntratumoralNANANA22258815
OV_2527Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman pancreatic cancer cell linePANC-1NANANANANAHsd:athymic nude mice xenografted for PANC-1 cell line(2.0E+6 cells)2.0E+6 pfuNA Decrease in tumor volume below 2 after 34 daysIntravenousNANANA22258815
OV_2813Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHT-291.0E+6 cells per wellNAMTT assay0.1 MOI100% cell survival after 24 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2814Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHT-291.0E+6 cells per wellNAMTT assay0.1 MOI50% cell survival after 48 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2815Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHT-291.0E+6 cells per wellNAMTT assay0.1 MOI20% cell survival after 72 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2816Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT151.0E+6 cells per wellNAMTT assay0.1 MOI100% cell survival after 24 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2817Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT151.0E+6 cells per wellNAMTT assay0.1 MOI100% cell survival after 48 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2818Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT151.0E+6 cells per wellNAMTT assay0.1 MOI100% cell survival after 72 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2819Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT-1161.0E+6 cells per wellNAMTT assay0.1 MOI100% cell survival after 24 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2820Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT-1161.0E+6 cells per wellNAMTT assay0.1 MOI20% cell survival after 48 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2821Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT-1161.0E+6 cells per wellNAMTT assay0.1 MOI20% cell survival after 72 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2822Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineSW6201.0E+6 cells per wellNAMTT assay0.1 MOI100% cell survival after 24 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2823Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineSW6201.0E+6 cells per wellNAMTT assay0.1 MOI90% cell survival after 48 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2824Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineSW6201.0E+6 cells per wellNAMTT assay0.1 MOI50% cell survival after 72 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2825Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineColo-2051.0E+6 cells per wellNAMTT assay0.1 MOI100% cell survival after 24 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2826Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineColo-2051.0E+6 cells per wellNAMTT assay0.1 MOI60% cell survival after 48 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2827Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineColo-2051.0E+6 cells per wellNAMTT assay0.1 MOI30% cell survival after 72 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2828Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHT-291.0E+6 cells per wellNAMTT assay1 MOI80% cell survival after 24 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2829Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHT-291.0E+6 cells per wellNAMTT assay1 MOI25% cell survival after 48 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2830Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHT-291.0E+6 cells per wellNAMTT assay1 MOI100% cell death after 72 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2831Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT151.0E+6 cells per wellNAMTT assay1 MOI80% cell survival after 24 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2832Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT151.0E+6 cells per wellNAMTT assay1 MOI60% cell survival after 48 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2833Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT151.0E+6 cells per wellNAMTT assay1 MOI60% cell survival after 72 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2834Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT-1161.0E+6 cells per wellNAMTT assay1 MOI60% cell survival after 24 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2835Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT-1161.0E+6 cells per wellNAMTT assay1 MOI40% cell survival after 48 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2836Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT-1161.0E+6 cells per wellNAMTT assay1 MOI100% cell death after 72 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2837Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineSW6201.0E+6 cells per wellNAMTT assay1 MOI80% cell survival after 24 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2838Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineSW6201.0E+6 cells per wellNAMTT assay1 MOI40% cell survival after 48 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2839Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineSW6201.0E+6 cells per wellNAMTT assay1 MOI100% cell death after 72 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2840Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineColo-2051.0E+6 cells per wellNAMTT assay1 MOI50% cell survival after 24 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2841Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineColo-2051.0E+6 cells per wellNAMTT assay1 MOI10% cell survival after 48 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2842Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineColo-2051.0E+6 cells per wellNAMTT assay1 MOI100% cell death after 72 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2843Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT-116NANANANANAHsd:athymic nude mice xenograft for HCT-116 (5.0E+6 cells)5.0E+6 pfuNA Significant reduction in tumor volume after 42 daysIntratumoralNANANA23531320
OV_2867Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureOsteosarcoma cell line143-B5.0E+3 cells per wellNAMTT assay0.01 MOI80% cell survivalNoNoNA No responseNANANANA23816608
OV_2868Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureOsteosarcoma cell line143-B5.0E+3 cells per wellNAMTT assay0.1 MOI70% cell survivalNoNoNA No responseNANANANA23816608
OV_2869Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureOsteosarcoma cell line143-B5.0E+3 cells per wellNAMTT assay1 MOI50% cell survivalNoNoNA No responseNANANANA23816608
OV_2870Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureOsteosarcoma cell line143-B5.0E+3 cells per wellNAMTT assay10 MOI40% cell survivalNoNoNA No responseNANANANA23816608
OV_2871Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureOsteosarcoma cell lineORD5.0E+3 cells per wellNAMTT assay0.01 MOI80% cell survivalNoNoNA No responseNANANANA23816608
OV_2872Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureOsteosarcoma cell lineORD5.0E+3 cells per wellNAMTT assay0.1 MOI50% cell survivalNoNoNA No responseNANANANA23816608
OV_2873Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureOsteosarcoma cell lineORD5.0E+3 cells per wellNAMTT assay1 MOI30% cell survivalNoNoNA No responseNANANANA23816608
OV_2874Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureOsteosarcoma cell lineORD5.0E+3 cells per wellNAMTT assay10 MOI20% cell survivalNoNoNA No responseNANANANA23816608
OV_2875Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureOsteosarcoma cell lineHOS5.0E+3 cells per wellNAMTT assay0.01 MOI30% cell survivalNoNoNA No responseNANANANA23816608
OV_2876Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureOsteosarcoma cell lineHOS5.0E+3 cells per wellNAMTT assay0.1 MOI20% cell survivalNoNoNA No responseNANANANA23816608
OV_2877Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureOsteosarcoma cell lineHOS5.0E+3 cells per wellNAMTT assay1 MOI10% cell survivalNoNoNA No responseNANANANA23816608