Primary information |
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OV_ID | OV_2868 |
Virus Name | Vaccinia virus |
Strain | vvDD |
Virus type | DNA |
Virus family | Poxviridae |
Modification in virus genome | Deletion of TK gene and vaccinia growth factor |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | Laboratory grown own culture |
Origin of cell line | Osteosarcoma cell line |
Cell line | 143-B |
Concentration of cell line | 5 |
In-vitro toxicity | NA |
Assay | MTT assay |
In-vitro virus concentration | 0.1 MOI |
In-vitro result | 70% cell survival |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | NA |
Immunogenic effect | NA |
Clinical trial | NA |
PMID | 23816608 |