Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1123	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Cervical cancer cell line	HeLaS3	1.0E+5 cells per well	NA	Fluoroscent mesure at 450nm	1MOI	25% cell viability	No	No	NA	No response		Apoptosis induction in cancer cell lines	NA	NA	15958641
OV_1124	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Cervical cancer cell line	C33A	1.0E+5 cells per well	NA	Fluoroscent mesure at 450nm	0.01MOI	40% cell viability	No	No	NA	No response		Apoptosis induction in cancer cell lines	NA	NA	15958641
OV_1125	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Cervical cancer cell line	C33A	1.0E+5 cells per well	NA	Fluoroscent mesure at 450nm	0.1MOI	25% cell viability	No	No	NA	No response		Apoptosis induction in cancer cell lines	NA	NA	15958641
OV_1126	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Cervical cancer cell line	C33A	1.0E+5 cells per well	NA	Fluoroscent mesure at 450nm	1MOI	5% cell viability	No	No	NA	No response		Apoptosis induction in cancer cell lines	NA	NA	15958641
OV_1127	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	Hamamatsu university school of medicine, japan	Ovarian cancer cell line	HOC-1	1.0E+5 cells per well	NA	Fluoroscent mesure at 450nm	0.01MOI	80% cell viability	No	No	NA	No response		Apoptosis induction in cancer cell lines	NA	NA	15958641
OV_1128	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	Hamamatsu university school of medicine, japan	Ovarian cancer cell line	HOC-1	1.0E+5 cells per well	NA	Fluoroscent mesure at 450nm	0.1MOI	50% cell viability	No	No	NA	No response		Apoptosis induction in cancer cell lines	NA	NA	15958641
OV_1129	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	Hamamatsu university school of medicine, japan	Ovarian cancer cell line	HOC-1	1.0E+5 cells per well	NA	Fluoroscent mesure at 450nm	1MOI	35% cell viability	No	No	NA	No response		Apoptosis induction in cancer cell lines	NA	NA	15958641
OV_1130	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	Tsukuba University, Japan	Ovarian cancer cell line	HAC-2	1.0E+5 cells per well	NA	Fluoroscent mesure at 450nm	0.01MOI	35% cell viability	No	No	NA	No response		Apoptosis induction in cancer cell lines	NA	NA	15958641
OV_1131	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	Tsukuba University, Japan	Ovarian cancer cell line	HAC-2	1.0E+5 cells per well	NA	Fluoroscent mesure at 450nm	0.1MOI	25% cell viability	No	No	NA	No response		Apoptosis induction in cancer cell lines	NA	NA	15958641
OV_1132	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	Tsukuba University, Japan	Ovarian cancer cell line	HAC-2	1.0E+5 cells per well	NA	Fluoroscent mesure at 450nm	1MOI	10% cell viability	No	No	NA	No response		Apoptosis induction in cancer cell lines	NA	NA	15958641
OV_1133	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	Osaka Medical college, japan	Ovarian cancer cell line	OMC-3	1.0E+5 cells per well	NA	Fluoroscent mesure at 450nm	0.01MOI	10% cell viability	No	No	NA	No response		Apoptosis induction in cancer cell lines	NA	NA	15958641
OV_1134	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	Osaka Medical college, japan	Ovarian cancer cell line	OMC-3	1.0E+5 cells per well	NA	Fluoroscent mesure at 450nm	0.1MOI	10% cell viability	No	No	NA	No response		Apoptosis induction in cancer cell lines	NA	NA	15958641
OV_1135	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	Osaka Medical college, japan	Ovarian cancer cell line	OMC-3	1.0E+5 cells per well	NA	Fluoroscent mesure at 450nm	1MOI	5% cell viability	No	No	NA	No response		Apoptosis induction in cancer cell lines	NA	NA	15958641
OV_1443	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	XTT assay	Log10 pfu/cell	20% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1444	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	A549	NA	NA	XTT assay	Log10 pfu/cell	Less than 10% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1445	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	HOP-62	NA	NA	XTT assay	Log10 pfu/cell	20% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1446	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	H322M	NA	NA	XTT assay	Log10 pfu/cell	70% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1447	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	H226	NA	NA	XTT assay	Log10 pfu/cell	70% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1448	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	EKVX	NA	NA	XTT assay	Log10 pfu/cell	30% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1449	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	XTT assay	Log10 pfu/cell	20% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1450	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	NCI-H522	NA	NA	XTT assay	Log10 pfu/cell	Less than 10% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1451	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	XTT assay	Log10 pfu/cell	30% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1452	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus strain in combination with palcitaxel (100 micromolar)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	Dose response analysis curve	Log10 pfu/cell	100% cell death after 4 days	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1453	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.003 +/- 0.001 micromolar, 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.903 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1454	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (38.50 +/- 16.01 micromolar, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.144 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1455	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.08 +/- 0.04 micromolar, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.577 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1456	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.294 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1457	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (77.79 +/- 25.08 micromolar, 1:20)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.543 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1458	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (>100 micromolar, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.069 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1459	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.003 +/- 0.001 micromolar, 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.221	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1460	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (38.50 +/- 16.01 micromolar, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.295	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1461	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.08 +/- 0.04 micromolar, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.303	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1462	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.440	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1463	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (77.79 +/- 25.08 micromolar, 1:20)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.344	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1464	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (>100 micromolar, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.092	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1465	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.003 +/- 0.001 micromolar, 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.057	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1466	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (38.50 +/- 16.01 micromolar, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.613	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1467	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.08 +/- 0.04 micromolar, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.159	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1468	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.660	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1469	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (77.79 +/- 25.08 micromolar, 1:20)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.218	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1470	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (>100 micromolar, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.133	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1471	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.003 +/- 0.001 micromolar, 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.193 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1472	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (38.50 +/- 16.01 micromolar, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.178 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1473	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.08 +/- 0.04 micromolar, 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.329 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1474	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.124 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1475	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (77.79 +/- 25.08 micromolar, 1:200)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.004 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1476	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (>100 micromolar, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.078 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1477	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.003 +/- 0.001 micromolar, 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.042	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1478	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (38.50 +/- 16.01 micromolar, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.420	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1479	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.08 +/- 0.04 micromolar, 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.061	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1480	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.216	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1481	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (77.79 +/- 25.08 micromolar, 1:200)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 1 Ã— 10â´	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1482	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (>100 micromolar, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.081	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1483	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.003 +/- 0.001 micromolar, 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.013	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1484	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (38.50 +/- 16.01 micromolar, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.994	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1485	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.08 +/- 0.04 micromolar, 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.011	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1486	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.374	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1487	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (77.79 +/- 25.08 micromolar, 1:200)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 4 Ã— 10â¶	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1488	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (>100 micromolar, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.084	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1489	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (5.31+/-1.21, ratio is 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.875	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1490	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (6.82+/- 3.22, ratio is 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.352	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1491	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (3.51+/- 1.15, ratio is 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.579	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1492	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (29.34+/- 6.62, ratio is 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.955	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1493	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (14.71+/- 6.60, ratio is 1:20)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.615	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1494	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (>100, ratio is 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1495	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (5.31+/-1.21, ratio is 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.313	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1496	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (6.82+/- 3.22, ratio is 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.325	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1497	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (3.51+/- 1.15, ratio is 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.487	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1498	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (29.34+/- 6.62, ratio is 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.559	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1499	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (14.71+/- 6.60, ratio is 1:20)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.297	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1500	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (>100, ratio is 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1501	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (5.31+/-1.21, ratio is 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.112	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1502	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (6.82+/- 3.22, ratio is 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.500	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1503	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (3.51+/- 1.15, ratio is 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.530	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1504	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (29.34+/- 6.62, ratio is 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.328	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1505	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (14.71+/- 6.60, ratio is 1:20)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.145	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1506	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (>100, ratio is 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1507	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (5.31+/-1.21, ratio is 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.061	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1508	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (6.82+/- 3.22, ratio is 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.053	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1509	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (3.51+/- 1.15, ratio is 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.546	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1510	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (29.34+/- 6.62, ratio is 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.933	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1511	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (14.71+/- 6.60, ratio is 1:200)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.558	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1512	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (>100, ratio is 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1513	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (5.31+/-1.21, ratio is 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.006	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1514	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (6.82+/- 3.22, ratio is 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.099	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1515	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (3.51+/- 1.15, ratio is 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.207	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1516	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (29.34+/- 6.62, ratio is 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1517	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (14.71+/- 6.60, ratio is 1:200)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.057	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1518	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (>100, ratio is 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1519	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (5.31+/-1.21, ratio is 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.129	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1520	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (6.82+/- 3.22, ratio is 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.195	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1521	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (3.51+/- 1.15, ratio is 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.342	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1522	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (29.34+/- 6.62, ratio is 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.610	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1523	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (14.71+/- 6.60, ratio is 1:200)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.013	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1524	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (>100, ratio is 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1525	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.01+/- 0.003, 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.199	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1526	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.83+/- 0.61, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.372	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1527	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.02+/- 0.01, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.630	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1528	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1529	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (17.69+/- 10.16, 1:20)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.112	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950

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