Detailed description page of Selected OV_ID


OV_1465 details
Primary information
OV_IDOV_1465
Virus Name Reovirus
StrainReoT3D
Virus typeRNA
Virus familyReoviridae
Modification in virus genomeNone
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with palcitaxel (0.003 +/- 0.001 micromolar, 1:53)
Immune gene induction in virus genomeNo
Source of cell lineNCI
Origin of cell lineHuman NSCLC cell line
Cell lineNCIH460
Concentration of cell line0
In-vitro toxicityNA
Assaychou-Talay analysis
In-vitro virus concentrationLog10 pfu/cell
In-vitro result90% cell death at CI value 0.057
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis, activation of caspase 3
Immunogenic effectNA
Clinical trialNA
PMID19594950