Detailed description page of Selected OV_ID


OV_1447 details
Primary information
OV_IDOV_1447
Virus Name Reovirus
StrainReoT3D
Virus typeRNA
Virus familyReoviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNCI
Origin of cell lineHuman NSCLC cell line
Cell lineH226
Concentration of cell line0
In-vitro toxicityNA
AssayXTT assay
In-vitro virus concentrationLog10 pfu/cell
In-vitro result70% cell survived 48 hours after post infection
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis, activation of caspase 3
Immunogenic effectNA
Clinical trialNA
PMID19594950