Detailed description page of Selected OV_ID


OV_1452 details
Primary information
OV_IDOV_1452
Virus Name Reovirus
StrainReoT3D
Virus typeRNA
Virus familyReoviridae
Modification in virus genomeNone
Virus aloneNo
Virus in combination iwth drug/radiationVirus strain in combination with palcitaxel (100 micromolar)
Immune gene induction in virus genomeNo
Source of cell lineNCI
Origin of cell lineHuman NSCLC cell line
Cell lineNCIH460
Concentration of cell line0
In-vitro toxicityNA
AssayDose response analysis curve
In-vitro virus concentrationLog10 pfu/cell
In-vitro result100% cell death after 4 days
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis, activation of caspase 3
Immunogenic effectNA
Clinical trialNA
PMID19594950