The Total number of records shown on this page is 32. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_4337	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human urinary bladder cancer cell line	T24	4000 cells per well	NA	MTT assay	100 MOI	30% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4338	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human hepatoblastoma	Huh-6	4000 cells per well	NA	MTT assay	0.001 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4339	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human hepatoblastoma	Huh-6	4000 cells per well	NA	MTT assay	0.01 MOI	98% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4340	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human hepatoblastoma	Huh-6	4000 cells per well	NA	MTT assay	0.1 MOI	90% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4341	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human hepatoblastoma	Huh-6	4000 cells per well	NA	MTT assay	10 MOI	78% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4342	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human hepatoblastoma	Huh-6	4000 cells per well	NA	MTT assay	100 MOI	62% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4343	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.001 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4344	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.01 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4345	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.1 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4346	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	10 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4347	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	100 MOI	90% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4348	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.001 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4349	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.01 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4350	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.1 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4351	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	10 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4352	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	100 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4353	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	Capan-1	4000 cells per well	NA	MTT assay	0.001 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4354	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	Capan-1	4000 cells per well	NA	MTT assay	0.01 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4355	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	Capan-1	4000 cells per well	NA	MTT assay	0.1 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4356	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	Capan-1	4000 cells per well	NA	MTT assay	10 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4357	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreatic adenocarcinoma cell line	Capan-1	4000 cells per well	NA	MTT assay	100 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4358	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with dbcAMP 100 micromoalr	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.001 MOI	40% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4359	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with dbcAMP 200 micromoalr	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.01 MOI	30% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4360	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with dbcAMP 400 micromoalr	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	0.1 MOI	30% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4361	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with dbcAMP 100 micromoalr	No	ATCC	Human pancreatic adenocarcinoma cell line	Capan-1	4000 cells per well	NA	MTT assay	0.001 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4362	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with dbcAMP 200 micromoalr	No	ATCC	Human pancreatic adenocarcinoma cell line	Capan-1	4000 cells per well	NA	MTT assay	0.01 MOI	60% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4363	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with dbcAMP 400 micromoalr	No	ATCC	Human pancreatic adenocarcinoma cell line	Capan-1	4000 cells per well	NA	MTT assay	0.1 MOI	30% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4364	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with 8-CPT-cAMP (20mg/kg/day)	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice subcutaneous xenograft for HCT-116 (5.0E+6)	3.0E+7 pfu	NA	Reduction in tumor volume to below 0.4 cubic centimeter after 22 days compared to control 1.2 cubic centimeter	Intravenous	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4365	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with 8-CPT-cAMP (20mg/kg/day)	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice subcutaneous xenograft for Hep3B (5.0E+6)	5.0E+6 pfu	NA	Reduction in tumor volume to below 1.5 cubic centimeter after 22 days compared to control 7.5 cubic centimeter	Intravenous	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4366	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with 8-CPT-cAMP (20mg/kg/day)	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice subcutaneous xenograft for Capan-1 (1.0E+7)	3.0E+7 pfu	NA	Reduction in tumor volume to below 0.2 cubic centimeter after 22 days compared to control 0.8 cubic centimeter	Intravenous	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4367	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Human liver cancer explant	5.0E+7 pfu	Slightly toxic to cancer cell	10.8% cancer cell growth inhibition	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4368	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with 8-CPT-cAMP (1 mmol/l)	No	NA	NA	NA	NA	NA	NA	NA	NA	Human liver cancer explant	5.0E+7 pfu	Slightly toxic to cancer cell	47% cancer cell growth inhibition	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347