The total number of records retrieved from this search are 5. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1258	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	Yes	No	VSV in combination with cisplatin (0.1 microgram/ml)	Virus expressing IL-12 gene	NA	NA	NA	NA	NA	NA	NA	NA	C3H/HeJ female mice orthotopic for SSC VII cell line	5.0E+8 pfu per kg	NA	Tumor size decreases to 0.5 cm² after 20 days	Intratumorally	NA	NA	NA	18043494
OV_1259	Vesicular stomatitis virus	Fusogenic strain	RNA	Rhabdoviridae	Yes , expressing fusion protein	No	VSV in combination with cisplatin (0.1 microgram/ml)	No	NA	NA	NA	NA	NA	NA	NA	NA	C3H/HeJ female mice orthotopic for SSC VII cell line	1.0E+7 pfu per kg	NA	Tumor size decreases to 0.5 cm² after 20 days	Intratumorally	NA	NA	NA	18043494
OV_4489	Herpes simplex virus	RH2	DNA	Herpesviridae	Mutant for Gamma 34.5 gene and gB gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	C3H mice subcutaneous implanted for SCCVII (1.0E+6)	50 microliter of RH2 virus, 3 times at interval of 2 days	NA	Tumor volume was less than 1587 cubic mm in treated mice compared to control 2996 cubic mm after 25 days	Intratumoral	Virus induced apoptosis	Increased extracellular ATP and HMGB1, indicating immunogenic cell death	NA	26987291
OV_5680	Reovirus	Reovirus strain T3D	RNA	Reoviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	C3H mice xenografted for ras transformed C3H cell line (1.0E+6)	5.0E+8 pfu	NA	Reduction in tumor volume to 60mm after 24 days	Intravenously	NA	NA	NA	US7964187
OV_5681	Reovirus	Reovirus strain T3D	RNA	Reoviridae	None	No	Virus strain in combination with cisplatin (2.5 mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	C3H mice xenografted for ras transformed C3H cell line (1.0E+6)	5.0E+8 pfu	NA	Reduction in tumor volume to 22mm after 24 days	Intravenously	NA	NA	NA	US7964187