Detailed description page of Selected OV_ID


OV_5681 details
Primary information
OV_IDOV_5681
Virus Name Reovirus
StrainReovirus strain T3D
Virus typeRNA
Virus familyReoviridae
Modification in virus genomeNone
Virus aloneNo
Virus in combination iwth drug/radiationVirus strain in combination with cisplatin (2.5 mg/kg)
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismC3H mice xenografted for ras transformed C3H cell line (1 ×10⁶)
In-vivo virus concentration5 ×10⁸ pfu
In-vivo toxicityNA
In-vivo resultReduction in tumor volume to 22mm after 24 days
Mode of deliveryIntravenously
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMIDUS7964187