Browse By Model Organism Result Page of OvirusTdb
The total number of records retrieved from this search are 54. Click on ID to see further detail.
IDOV_5763 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1887.6mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5764 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1181.4mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5765 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 74.4mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5766 | Virus nameVaccinia virus | Virus strainGLV-1h82 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 855.9mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5767 | Virus nameVaccinia virus | Virus strainGLV-1h83 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1392mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5768 | Virus nameVaccinia virus | Virus strainGLV-1h86 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 187.5mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5769 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 264.9mm compared to control 204.3 mm after 32 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5770 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 365.7mm compared to control 333.9 mm after 42 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5771 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 155.3mm compared to control 646.6 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5772 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 62mm compared to control 886.4 mm after 56 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5773 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (25mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 291.1mm compared to control 204.3 mm after 32 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5774 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (25mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 314.2mm compared to control 333.9 mm after 42 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5775 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (25mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 238.3mm compared to control 646.6 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5776 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (25mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 117.4mm compared to control 886.4 mm after 56 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5777 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (50mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 279.8mm compared to control 204.3 mm after 32 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5778 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (50mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 395.5mm compared to control 333.9 mm after 42 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5779 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (50mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 206.5mm compared to control 646.6 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5780 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (50mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 61mm compared to control 886.4 mm after 56 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5781 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (100mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 587.1mm compared to control 204.3 mm after 32 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5782 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (100mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 391.1mm compared to control 333.9 mm after 42 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5783 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (100mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 184mm compared to control 646.6 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5784 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (100mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 58mm compared to control 886.4 mm after 56 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5785 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 176.9 mm compared to control 278.1 after 53 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5786 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 598.8mm compared to control 755 after 63 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5787 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 668.4 mm compared to control 1169.9 after 69 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5788 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 896.6 mm compared to control 2512.7 after 77 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5789 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 298.8 after 41 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5790 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1448.3 after 55 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5791 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 2512.4 after 64 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5792 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 34.07 after 71 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5793 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 415.1 after 41 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5794 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1403.1 after 55 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5795 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1163.7 after 64 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5796 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 993 after 71 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5797 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 757.5 after 79 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5798 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 667 after 87 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5799 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 547 after 93 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5800 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 549 after 99 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5801 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 511 after 106 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5802 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 465.3 after 113 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5803 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 441.3 after 119 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5804 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 268.4 after 55 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5805 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 623.7 after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5806 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 1232.5 after 70 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5807 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 1277.05 after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5808 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 1189.55 mm after 81 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5809 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 744.4mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5810 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 402.1 after 55 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5811 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 1128.15 after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5812 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 1485.05 after 70 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5813 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 1599.35 after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5814 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 1411.4mm after 81 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5815 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 1040mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5816 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 906.75 mm after 96 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |