Browse By Model Organism Result Page of OvirusTdb

The total number of records retrieved from this search are 100. Click on ID to see further detail.
IDOV_5685Virus nameVaccinia virusVirus strainGLV-1h71Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 208.8mm compared to control 240.8 mm after 33 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5686Virus nameVaccinia virusVirus strainGLV-1h72Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 157.2mm compared to control 240.8 mm after 33 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5687Virus nameVaccinia virusVirus strainGLV-1h73Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 280.3mm compared to control 240.8 mm after 33 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5688Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 301.9mm compared to control 240.8 mm after 33 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5689Virus nameVaccinia virusVirus strainGLV-1h22Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 273.5mm compared to control 263.6 mm after 36 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5690Virus nameVaccinia virusVirus strainGLV-1h68Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 243.8mm compared to control 263.6 mm after 36 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5691Virus nameVaccinia virusVirus strainGLV-1h70Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 286mm compared to control 263.6 mm after 36 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5692Virus nameVaccinia virusVirus strainGLV-1h71Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 267.1mm compared to control 263.6 mm after 36 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5693Virus nameVaccinia virusVirus strainGLV-1h72Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 155.6mm compared to control 263.6 mm after 36 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5694Virus nameVaccinia virusVirus strainGLV-1h73Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 310.9mm compared to control 263.6 mm after 36 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5695Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 416.9mm compared to control 263.6 mm after 36 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5696Virus nameVaccinia virusVirus strainGLV-1h22Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 536.1mm compared to control 579.1 mm after 43 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5697Virus nameVaccinia virusVirus strainGLV-1h68Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 5550.4mm compared to control 579.1 mm after 43 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5698Virus nameVaccinia virusVirus strainGLV-1h70Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 463.4mm compared to control 579.1 mm after 43 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5699Virus nameVaccinia virusVirus strainGLV-1h71Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 543.3mm compared to control 579.1 mm after 43 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5700Virus nameVaccinia virusVirus strainGLV-1h72Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 320.1mm compared to control 579.1 mm after 43 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5701Virus nameVaccinia virusVirus strainGLV-1h73Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 679mm compared to control 579.1 mm after 43 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5702Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 660mm compared to control 579.1 mm after 43 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5703Virus nameVaccinia virusVirus strainGLV-1h22Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 701.4mm compared to control 636.4 mm after 50 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5704Virus nameVaccinia virusVirus strainGLV-1h68Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 761.3mm compared to control 636.4 mm after 50 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5705Virus nameVaccinia virusVirus strainGLV-1h70Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 706.6mm compared to control 636.4 mm after 50 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5706Virus nameVaccinia virusVirus strainGLV-1h71Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 721.3mm compared to control 636.4 mm after 50 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5707Virus nameVaccinia virusVirus strainGLV-1h72Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 476.3mm compared to control 636.4 mm after 50 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5708Virus nameVaccinia virusVirus strainGLV-1h73Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 864.1mm compared to control 636.4 mm after 50 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5709Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 828.6mm compared to control 636.4 mm after 50 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5710Virus nameVaccinia virusVirus strainGLV-1h22Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 978.4mm compared to control 671.6 mm after 57 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5711Virus nameVaccinia virusVirus strainGLV-1h68Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 852mm compared to control 671.6 mm after 57 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5712Virus nameVaccinia virusVirus strainGLV-1h70Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 985.5mm compared to control 671.6 mm after 57 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5713Virus nameVaccinia virusVirus strainGLV-1h71Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 936.1mm compared to control 671.6 mm after 57 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5714Virus nameVaccinia virusVirus strainGLV-1h72Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 695mm compared to control 671.6 mm after 57 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5715Virus nameVaccinia virusVirus strainGLV-1h73Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 1179.9mm compared to control 671.6 mm after 57 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5716Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 897.4mm compared to control 671.6 mm after 57 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5717Virus nameVaccinia virusVirus strainGLV-1h22Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 1485mm compared to control 2715 mm after 92 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5718Virus nameVaccinia virusVirus strainGLV-1h68Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 1053mm compared to control 2715 mm after 92 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5719Virus nameVaccinia virusVirus strainGLV-1h70Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 852mm compared to control 2715 mm after 92 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5720Virus nameVaccinia virusVirus strainGLV-1h71Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 606mm compared to control 2715 mm after 92 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5721Virus nameVaccinia virusVirus strainGLV-1h72Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 751mm compared to control 2715 mm after 92 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5722Virus nameVaccinia virusVirus strainGLV-1h73Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 166.7mm compared to control 2715 mm after 92 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5723Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultComplete regression in tumor volume after 92 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5724Virus nameVaccinia virusVirus strainGLV-1h22Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 1536.9mm compared to control 2918.3 mm after 97 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5725Virus nameVaccinia virusVirus strainGLV-1h68Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 962.2mm compared to control 2918.3 mm after 97 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5726Virus nameVaccinia virusVirus strainGLV-1h70Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 579.2mm compared to control 2918.3 mm after 97 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5727Virus nameVaccinia virusVirus strainGLV-1h71Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 546.9mm compared to control 2918.3 mm after 97 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5728Virus nameVaccinia virusVirus strainGLV-1h72Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 720.1mm compared to control 2918.3 mm after 97 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5729Virus nameVaccinia virusVirus strainGLV-1h73Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 117.8mm compared to control 2918.3 mm after 97 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5730Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultComplete regression in tumor volume after 97 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5731Virus nameVaccinia virusVirus strainGLV-1h22Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 412.9mm after 39 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5732Virus nameVaccinia virusVirus strainGLV-1h68Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 350.2mm after 39 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5733Virus nameVaccinia virusVirus strainGLV-1h73Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 341.1mm after 39 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5734Virus nameVaccinia virusVirus strainGLV-1h82Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 353.4mm after 39 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5735Virus nameVaccinia virusVirus strainGLV-1h83Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 392.25mm after 39 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5736Virus nameVaccinia virusVirus strainGLV-1h84Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 305.6mm after 39 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5737Virus nameVaccinia virusVirus strainGLV-1h85Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 350.65mm after 39 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5738Virus nameVaccinia virusVirus strainGLV-1h86Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 419.55mm after 39 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5739Virus nameVaccinia virusVirus strainGLV-1h22Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 750.4mm after 47 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5740Virus nameVaccinia virusVirus strainGLV-1h68Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 722.3mm after 47 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5741Virus nameVaccinia virusVirus strainGLV-1h73Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 819.8mm after 47 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5742Virus nameVaccinia virusVirus strainGLV-1h82Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 1081.2mm after 47 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5743Virus nameVaccinia virusVirus strainGLV-1h83Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 1222.25mm after 47 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5744Virus nameVaccinia virusVirus strainGLV-1h84Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 604.3mm after 47 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5745Virus nameVaccinia virusVirus strainGLV-1h85Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 914mm after 47 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5746Virus nameVaccinia virusVirus strainGLV-1h86Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 962.1mm after 47 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5747Virus nameVaccinia virusVirus strainGLV-1h22Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 1424.4mm after 62 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5748Virus nameVaccinia virusVirus strainGLV-1h68Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 1390.35mm after 62 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5749Virus nameVaccinia virusVirus strainGLV-1h73Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 983.2mm after 62 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5750Virus nameVaccinia virusVirus strainGLV-1h82Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 1319.2mm after 62 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5751Virus nameVaccinia virusVirus strainGLV-1h83Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 1686.05mm after 62 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5752Virus nameVaccinia virusVirus strainGLV-1h84Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 982mm after 62 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5753Virus nameVaccinia virusVirus strainGLV-1h85Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 947.2mm after 62 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5754Virus nameVaccinia virusVirus strainGLV-1h86Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 1397.55mm after 62 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5755Virus nameVaccinia virusVirus strainGLV-1h22Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 1907.5mm after 75 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5756Virus nameVaccinia virusVirus strainGLV-1h68Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 1528.95mm after 75 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5757Virus nameVaccinia virusVirus strainGLV-1h73Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 517.3mm after 75 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5758Virus nameVaccinia virusVirus strainGLV-1h82Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 1211.8mm after 75 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5759Virus nameVaccinia virusVirus strainGLV-1h83Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 1856.35mm after 75 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5760Virus nameVaccinia virusVirus strainGLV-1h84Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 614.25mm after 75 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5761Virus nameVaccinia virusVirus strainGLV-1h85Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 255.25mm after 75 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5762Virus nameVaccinia virusVirus strainGLV-1h86Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 689.6mm after 75 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5763Virus nameVaccinia virusVirus strainGLV-1h22Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 1887.6mm after 89 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5764Virus nameVaccinia virusVirus strainGLV-1h68Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 1181.4mm after 89 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5765Virus nameVaccinia virusVirus strainGLV-1h73Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 74.4mm after 89 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5766Virus nameVaccinia virusVirus strainGLV-1h82Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 855.9mm after 89 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5767Virus nameVaccinia virusVirus strainGLV-1h83Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 1392mm after 89 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5768Virus nameVaccinia virusVirus strainGLV-1h86Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume becomes 187.5mm after 89 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5769Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 264.9mm compared to control 204.3 mm after 32 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5770Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 365.7mm compared to control 333.9 mm after 42 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5771Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 155.3mm compared to control 646.6 mm after 50 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5772Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 62mm compared to control 886.4 mm after 56 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5773Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneNoVirus in combination with drug/radiationVirus in combination with cidofovir (25mg/kg)Immune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 291.1mm compared to control 204.3 mm after 32 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5774Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneNoVirus in combination with drug/radiationVirus in combination with cidofovir (25mg/kg)Immune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 314.2mm compared to control 333.9 mm after 42 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5775Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneNoVirus in combination with drug/radiationVirus in combination with cidofovir (25mg/kg)Immune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 238.3mm compared to control 646.6 mm after 50 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5776Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneNoVirus in combination with drug/radiationVirus in combination with cidofovir (25mg/kg)Immune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 117.4mm compared to control 886.4 mm after 56 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5777Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneNoVirus in combination with drug/radiationVirus in combination with cidofovir (50mg/kg)Immune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 279.8mm compared to control 204.3 mm after 32 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5778Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneNoVirus in combination with drug/radiationVirus in combination with cidofovir (50mg/kg)Immune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 395.5mm compared to control 333.9 mm after 42 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5779Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneNoVirus in combination with drug/radiationVirus in combination with cidofovir (50mg/kg)Immune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 206.5mm compared to control 646.6 mm after 50 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5780Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneNoVirus in combination with drug/radiationVirus in combination with cidofovir (50mg/kg)Immune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 61mm compared to control 886.4 mm after 56 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5781Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneNoVirus in combination with drug/radiationVirus in combination with cidofovir (100mg/kg)Immune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 587.1mm compared to control 204.3 mm after 32 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5782Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneNoVirus in combination with drug/radiationVirus in combination with cidofovir (100mg/kg)Immune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 391.1mm compared to control 333.9 mm after 42 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5783Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneNoVirus in combination with drug/radiationVirus in combination with cidofovir (100mg/kg)Immune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 184mm compared to control 646.6 mm after 50 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968
IDOV_5784Virus nameVaccinia virusVirus strainGLV-1h74Virus genome typeDNAVirus familyPoxviridaeVirus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAVirus aloneNoVirus in combination with drug/radiationVirus in combination with cidofovir (100mg/kg)Immune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)In-vivo virus concentration5.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume become 58mm compared to control 886.4 mm after 56 daysMode of deliveryIntravenouslyPathway inducedInduction of apoptosisImmunogenic effectNAClinical trialNAPMIDUS8052968