The total number of records retrieved from this search are 71. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_133	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁶ MOI	1% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_134	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁶ MOI	1% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_135	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁶ MOI	25% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_136	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁶ MOI	16% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_137	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁵ MOI	1% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_138	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁵ MOI	5% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_139	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁵ MOI	20% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_140	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁵ MOI	32% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_141	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁴ MOI	3% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_142	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁴ MOI	10% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_143	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁴ MOI	30% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_144	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁴ MOI	32% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_145	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻³ MOI	15% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_146	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻³ MOI	10% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_147	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻³ MOI	33% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_148	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻³ MOI	51% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_149	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻² MOI	20% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_150	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻² MOI	26% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_151	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻² MOI	49% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_152	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻² MOI	98% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_153	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻¹ MOI	25% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_154	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻¹ MOI	40% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_155	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻¹ MOI	54% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_156	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻¹ MOI	58% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_157	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	1 MOI	28% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_158	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	1 MOI	45% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_159	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	1 MOI	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_160	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	1 MOI	58% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_161	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3 MOI	30% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_162	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3 MOI	40% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_163	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3 MOI	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_164	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3 MOI	70% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_165	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁷ MOI	5% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_166	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁷ MOI	10% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_167	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁷ MOI	10% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_168	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁶ MOI	9% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_169	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁶ MOI	6% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_170	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁶ MOI	3% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_171	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁵ MOI	15% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_172	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁵ MOI	10% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_173	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁵ MOI	5% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_174	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁴ MOI	40% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_175	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁴ MOI	44% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_176	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁴ MOI	43% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_177	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻³ MOI	49% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_178	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻³ MOI	46% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_179	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻³ MOI	42% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_180	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻² MOI	51% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_181	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻² MOI	52% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_182	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻² MOI	52% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_183	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻¹ MOI	51% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_184	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻¹ MOI	52% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_185	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻¹ MOI	52% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_186	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	1 MOI	51% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_187	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	1 MOI	52% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_188	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	1 MOI	52% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_189	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3 MOI	54% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_190	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3 MOI	52% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_191	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3 MOI	60% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_2254	Herpes simplex virus	Equine Herpesvirus type-1	DNA	Herpesviridae	None	Yes	No	No	NA	Human glioma cell line	U251	NA	NA	MTS assay	1 MOI	98% cell survival after 48 hours	No	No	NA	No response	NA	NA	NA	NA	22205738
OV_2259	Herpes simplex virus	Equine Herpesvirus type-1	DNA	Herpesviridae	None	Yes	No	No	NA	Human glioma cell line	U251	NA	NA	MTS assay	3 MOI	90% cell survival after 48 hours	No	No	NA	No response	NA	NA	NA	NA	22205738
OV_2264	Herpes simplex virus	Equine Herpesvirus type-1	DNA	Herpesviridae	None	Yes	No	No	NA	Human glioma cell line	U251	NA	NA	MTS assay	10 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	NA	NA	NA	22205738
OV_3502	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	Chinese academy of science	Human neuroglioma cell line	U251	NA	NA	MTT assay	0.1 MOI	100% cell survival	No	No	NA	No response	NA	Induction of apoptosis as measured by Propidium iodide method and annexin V-FITC staining	NA	NA	28672936
OV_3503	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	Chinese academy of science	Human neuroglioma cell line	U251	NA	NA	MTT assay	0.5 MOI	82% cell survival	No	No	NA	No response	NA	Induction of apoptosis as measured by Propidium iodide method and annexin V-FITC staining	NA	NA	28672936
OV_3504	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	Chinese academy of science	Human neuroglioma cell line	U251	NA	NA	MTT assay	1 MOI	78% cell survival	No	No	NA	No response	NA	Induction of apoptosis as measured by Propidium iodide method and annexin V-FITC staining	NA	NA	28672936
OV_3505	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	Chinese academy of science	Human neuroglioma cell line	U251	NA	NA	MTT assay	5 MOI	40% cell survival	No	No	NA	No response	NA	Induction of apoptosis as measured by Propidium iodide method and annexin V-FITC staining	NA	NA	28672936
OV_3506	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	Chinese academy of science	Human neuroglioma cell line	U251	NA	NA	MTT assay	10 MOI	18% cell survival	No	No	NA	No response	NA	Induction of apoptosis as measured by Propidium iodide method and annexin V-FITC staining	NA	NA	28672936
OV_3512	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	Chinese academy of science	Human neuroglioma cell line	U251	NA	NA	MTT assay	5 MOI	92% cell viability after day 1	No	No	NA	No response	NA	Induction of apoptosis as measured by Propidium iodide method and annexin V-FITC staining	NA	NA	28672936
OV_3513	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	Chinese academy of science	Human neuroglioma cell line	U251	NA	NA	MTT assay	5 MOI	62% cell viability after day 2	No	No	NA	No response	NA	Induction of apoptosis as measured by Propidium iodide method and annexin V-FITC staining	NA	NA	28672936
OV_3514	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	Chinese academy of science	Human neuroglioma cell line	U251	NA	NA	MTT assay	5 MOI	35% cell viability after day 3	No	No	NA	No response	NA	Induction of apoptosis as measured by Propidium iodide method and annexin V-FITC staining	NA	NA	28672936
OV_4285	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human glioblastoma	U251	4000 cells per well	NA	MTT assay	10 pfu	34.7 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347