The total number of records retrieved from this search are 129. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_414	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	0.4 MOI	35% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_415	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	0.4 MOI	35% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_416	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	1 MOI	24% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_417	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	1 MOI	20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_418	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	4 MOI	20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_419	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	4 MOI	21% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_420	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	11 MOI	19% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_421	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	11 MOI	19% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_422	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	33 MOI	12% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_423	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	33 MOI	16% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_424	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	100 MOI	8% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_425	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	100 MOI	12% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_438	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	0.4 MOI	88% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_439	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	0.4 MOI	46% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_440	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	1 MOI	62% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_441	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	1 MOI	20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_442	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	4 MOI	26% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_443	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	4 MOI	22% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_444	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	11 MOI	24% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_445	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	11 MOI	20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_446	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	33 MOI	20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_447	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	33 MOI	18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_448	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	100 MOI	18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_449	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	100 MOI	16% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_450	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	No	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	0.4 MOI	90% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_451	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	No	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	0.4 MOI	58% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_452	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	No	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	1 MOI	74% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_453	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	No	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	1 MOI	22% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_454	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	No	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	4 MOI	28% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_455	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	No	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	4 MOI	20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_456	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	No	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	11 MOI	19% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_457	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	No	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	11 MOI	19% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_458	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	No	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	33 MOI	18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_459	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	No	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	33 MOI	14% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_460	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	No	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	100 MOI	14% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_461	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	No	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	100 MOI	14% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_462	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	0.4 MOI	56% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_463	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	0.4 MOI	58% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_464	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	1 MOI	24% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_465	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	1 MOI	20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_466	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	4 MOI	20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_467	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	4 MOI	20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_468	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	11 MOI	19% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_469	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	11 MOI	19% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_470	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	33 MOI	18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_471	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	33 MOI	16% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_472	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	100 MOI	14% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_473	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	100 MOI	12% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_474	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with ING4	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	0.4 MOI	30% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_475	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with ING4	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	0.4 MOI	38% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_476	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with ING4	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	1 MOI	22% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_477	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with ING4	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	1 MOI	18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_478	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with ING4	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	4 MOI	20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_479	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with ING4	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	4 MOI	18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_480	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with ING4	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	11 MOI	19% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_481	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with ING4	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	11 MOI	18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_482	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with ING4	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	33 MOI	18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_483	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with ING4	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	33 MOI	16% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_484	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with ING4	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3ip.1 OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	100 MOI	14% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_485	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	No	Viral starin in combination with ING4	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovary cancer cell line	SKOV3luc OvCa	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	100 MOI	14% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_842	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	NA	Epithelial ovarian carcinoma	SKOV3	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	0.01 MOI	35% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_4711	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.001 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4712	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4713	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4714	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4715	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	50% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4726	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.001 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4727	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4728	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4729	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	75% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4730	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	65% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4741	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.001 MOI	5% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4742	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	4% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4743	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	3% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4744	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	3% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4745	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	1% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4755	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4756	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4757	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4758	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4767	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4768	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4769	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	75% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4770	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	75% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4779	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	30% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4780	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	15% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4781	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	15% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4782	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	15% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4802	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4803	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4804	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	60% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4805	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4806	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	70% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4807	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	20% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4808	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	60% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4809	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	40% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4810	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	10% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4811	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	60% cell viability after 4 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4812	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	20% cell viability after 4 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4813	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	1% cell viability after 4 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4814	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	50% cell viability after 5 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4815	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	2% cell viability after 5 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4816	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	2% cell viability after 5 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4847	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4848	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4849	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	80% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4850	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4851	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4852	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	40% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4853	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4854	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	90% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4855	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	10% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4856	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 4 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4857	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	70% cell viability after 4 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4858	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	20% cell viability after 4 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4859	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 5 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4860	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	60% cell viability after 5 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4861	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	20% cell viability after 5 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_5071	Avian orthoreovirus	ARV-PB1	RNA	Reoviridae	None	Yes	No	No	ATCC	Human epithelial ovarian carcinoma	SKOV3	1.0E+3 cells per well	NA	Crystal violet staining	10 MOI	70% cell viability after 96 hours	No	No	NA	No response	NA	Induction of apoptosis	Induction of Interferon related gene expression	NA	28441762
OV_5305	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	SKOV3	4000 cells per well	NA	Alamar blue assay	0.1 PFU	100% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5306	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	SKOV3	4000 cells per well	NA	Alamar blue assay	0.33 PFU	98% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5307	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	SKOV3	4000 cells per well	NA	Alamar blue assay	1 PFU	50% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5308	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	SKOV3	4000 cells per well	NA	Alamar blue assay	3.3 PFU	18% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5309	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	SKOV3	4000 cells per well	NA	Alamar blue assay	10 PFU	15% cell viable	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5310	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	SKOV3	4000 cells per well	NA	Alamar blue assay	33 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5311	Herpes simplex virus	M032	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 gene	Yes	No	Virus expressing murine IL-12	NA	Human ovarian cancer cell line	SKOV3	4000 cells per well	NA	Alamar blue assay	100 PFU	100% cell killing	No	No	NA	No response	NA	NA	Tumor specific T cell response induced	NA	27784340
OV_5611	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human ovarian sarcoma cell line	SKOV3	80% confluency	NA	MTT assay	24 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5830	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human ovarian carcinoma cell line	SKOV3	80% confluency	NA	NA	24 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5892	Adenovirus	CGTG-602	DNA	Adenoviridae	Virus E1A promoter is replaced by human E2F1 promoter	Yes	No	No	ATCC	Human ovarian carcinoma cell line	SKOV3	NA	NA	MTT assay	1 ×10⁴ pfu	80% of cancer cell death occurs after 100 days	No	No	NA	No response	NA	NA	NA	NA	US9410129