Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 60. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_861Herpes simplex virusBL1DNAHerpesviridaeNoneYesNoNoATCCTriple-negative breast cancer cell lineMDA-MB-231NANAMTT assay1 MOI75 % cancerous cell killing after 24 hoursNoNoNA No responseNANANANA12595888
OV_864Herpes simplex virusBL1DNAHerpesviridaeNoneYesNoNoATCCTriple-negative breast cancer cell lineMDA-MB-231NANAMTT assay1 MOI92% cancerous cell killing after 48 hoursNoNoNA No responseNANANANA12595888
OV_867Herpes simplex virusBL1DNAHerpesviridaeNoneYesNoNoATCCTriple-negative breast cancer cell lineMDA-MB-231NANAMTT assay0.1 MOI40 % cancerous cell killing after 24 hoursNoNoNA No responseNANANANA12595888
OV_870Herpes simplex virusBL1DNAHerpesviridaeNoneYesNoNoATCCTriple-negative breast cancer cell lineMDA-MB-231NANAMTT assay0.1 MOI80% cancerous cell killing after 48 hoursNoNoNA No responseNANANANA12595888
OV_873Herpes simplex virusJS1DNAHerpesviridaeNoneYesNoNoATCCTriple-negative breast cancer cell lineMDA-MB-231NANAMTT assay1 MOI85 % cancerous cell killing after 24 hoursNoNoNA No responseNANANANA12595888
OV_876Herpes simplex virusJS1DNAHerpesviridaeNoneYesNoNoATCCTriple-negative breast cancer cell lineMDA-MB-231NANAMTT assay1 MOI96% cancerous cell killing after 48 hoursNoNoNA No responseNANANANA12595888
OV_879Herpes simplex virusJS1DNAHerpesviridaeNoneYesNoNoATCCTriple-negative breast cancer cell lineMDA-MB-231NANAMTT assay0.1 MOI60 % cancerous cell killing after 24 hoursNoNoNA No responseNANANANA12595888
OV_882Herpes simplex virusJS1DNAHerpesviridaeNoneYesNoNoATCCTriple-negative breast cancer cell lineMDA-MB-231NANAMTT assay0.1 MOI88% cancerous cell killing after 48 hoursNoNoNA No responseNANANANA12595888
OV_2442Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer0.01 MOI100% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2443Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer0.01 MOI100% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2444Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer0.01 MOI100% cell survival after day 5NoNoNA No responseNANANANA22258815
OV_2445Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer0.01 MOI100% cell survival after day 7NoNoNA No responseNANANANA22258815
OV_2446Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer0.01 MOI100% cell survival after day 9NoNoNA No responseNANANANA22258815
OV_2482Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI90% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2483Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI90% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2484Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI90% cell survival after day 5NoNoNA No responseNANANANA22258815
OV_2485Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI90% cell survival after day 7NoNoNA No responseNANANANA22258815
OV_2518Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer1 MOI70% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2519Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer1 MOI10% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2520Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer1 MOI10% cell survival after day 5NoNoNA No responseNANANANA22258815
OV_2521Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman breast cancer cell lineMDA-MB-2313.0E+4 cells per wellNALDH release and spectrophometer1 MOI10% cell survival after day 7NoNoNA No responseNANANANA22258815
OV_2579AdenovirusCNHK600-IL24DNAAdenoviridaeDeletion of E1B gene and addition of IL-24 geneYesNoVirus expressing IL-24 geneShanghai laboratory animal center, ChinaHuman breast cancer cell lineMDA-MB-2311.0E+5 cells per wellNAMTT assay0.1 MOI100% cell survivalNoNoNA No responseNAInduction of apoptosis in cancerNANA22640485
OV_2580AdenovirusCNHK600-IL24DNAAdenoviridaeDeletion of E1B gene and addition of IL-24 geneYesNoVirus expressing IL-24 geneShanghai laboratory animal center, ChinaHuman breast cancer cell lineMDA-MB-2311.0E+5 cells per wellNAMTT assay1 MOI100% cell survivalNoNoNA No responseNAInduction of apoptosis in cancerNANA22640485
OV_2581AdenovirusCNHK600-IL24DNAAdenoviridaeDeletion of E1B gene and addition of IL-24 geneYesNoVirus expressing IL-24 geneShanghai laboratory animal center, ChinaHuman breast cancer cell lineMDA-MB-2311.0E+5 cells per wellNAMTT assay10 MOI50% cell survivalNoNoNA No responseNAInduction of apoptosis in cancerNANA22640485
OV_2582AdenovirusCNHK600-IL24DNAAdenoviridaeDeletion of E1B gene and addition of IL-24 geneYesNoVirus expressing IL-24 geneShanghai laboratory animal center, ChinaHuman breast cancer cell lineMDA-MB-2311.0E+5 cells per wellNAMTT assay100 MOI20% cell survivalNoNoNA No responseNAInduction of apoptosis in cancerNANA22640485
OV_2583AdenovirusCNHK600-IL24DNAAdenoviridaeDeletion of E1B gene and addition of IL-24 geneYesNoVirus expressing IL-24 geneShanghai laboratory animal center, ChinaHuman breast cancer cell lineMDA-MB-2311.0E+5 cells per wellNAMTT assay1000 MOI10% cell survivalNoNoNA No responseNAInduction of apoptosis in cancerNANA22640485
OV_2584AdenovirusCNHK600-IL24DNAAdenoviridaeDeletion of E1B gene and addition of IL-24 geneYesNoVirus expressing IL-24 geneShanghai laboratory animal center, ChinaHuman breast cancer cell lineMDA-MB-2311.0E+5 cells per wellNAMTT assay10000 MOIAll cells are deadNoNoNA No responseNAInduction of apoptosis in cancerNANA22640485
OV_2585AdenovirusCNHK600-IL24DNAAdenoviridaeDeletion of E1B gene and addition of IL-24 geneYesNoVirus expressing IL-24 geneShanghai laboratory animal center, ChinaHuman breast cancer cell lineMDA-MB-231NANANANANANu/Nu female mice orthotopic for MDA-MB-231 cell line (8.0E+7 cells)1.0E+8 pfuNA Tumor volume comes to 1000mm as compared to normal 2000 after 42 daysIntratumoralInduction of apoptosis in cancerNANA22640485
OV_2586AdenovirusCNHK600-IL24DNAAdenoviridaeDeletion of E1B gene and addition of IL-24 geneYesNoVirus expressing IL-24 geneShanghai laboratory animal center, ChinaHuman breast cancer cell lineMDA-MB-231NANANANANANu/Nu female mice orthotopic for MDA-MB-231 cell line (8.0E+7 cells)2.0E+8 pfuNA Tumor volume comes to below 1000mm as compared to normal 2000 after 42 daysIntratumoralInduction of apoptosis in cancerNANA22640485
OV_2587AdenovirusCNHK600-IL24DNAAdenoviridaeDeletion of E1B gene and addition of IL-24 geneYesNoVirus expressing IL-24 geneShanghai laboratory animal center, ChinaHuman breast cancer cell lineMDA-MB-231NANANANANANu/Nu female mice orthotopic for MDA-MB-231 cell line (8.0E+7 cells)4.0E+8 pfuNA Tumor volume comes to 500mm as compared to normal 2000 after 42 daysIntratumoralInduction of apoptosis in cancerUpregulation of GADD34NA22640485
OV_2632AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseYesNoNoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay1 MOI80% cell survival after 3 daysNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2633AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseYesNoNoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay1 MOI60% cell survival after 6 daysNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2636AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug Bvdu (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay1 MOI70% cell survival after 3 daysNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2637AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug Bvdu (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay1 MOI30% cell survival after 6 daysNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2638AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay1 MOI60% cell survival after 3 daysNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2639AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay1 MOI20% cell survival after 6 daysNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2644AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug Bvdu (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay0.001 MOI80% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2645AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug Bvdu (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay0.01 MOI80% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2646AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug Bvdu (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay0.1 MOI60% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2647AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug Bvdu (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay1 MOI50% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2648AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug Bvdu (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay10 MOI40% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2649AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay0.001 MOI80% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2650AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay0.01 MOI70% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2651AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay0.1 MOI40% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2652AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay1 MOI20% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2653AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay10 MOI10% cell survivalNoNoNA No responseNACombination of drug and virus increase the apoptosis processNANA23000515
OV_2664AdenovirusSG500-dNKDNAAdenoviridaeAddition of deoxyribonucleoside kinaseNoVirus in combination with drug dFdC (1 micromolar)NoShanghai cell collectionHuman breast cancer cell lineMDA-MB-231NANANANANABALB/c nude mice xenograft for MDA-MB-231(5.0E+6 cells)1.0E+9 pfuNA Increase in median survival time to more than 100 days compared to control and reduction in tumor volume 663.85 +/- 379.39mm compared to control 1336.46 +/- 614.81NACombination of drug and virus increase the apoptosis processNANA23000515
OV_2938Newcastle disease viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman mammary cancer cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay2⁴.⁷ HAU/mlCell viability reduced below 20%NoNoNA No responseNAInduction of apoptosis as measured by TUNEL assay (44.52 +/- 10.13) after 72 hoursNANA25821783
OV_4301AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman breast adenocarcinomaMDA-MB-2314000 cells per wellNAMTT assay10 pfu58.9 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_5043Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay0.1 MOI40% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5044Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay1 MOI30% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5045Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay10 MOI20% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5046Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay0.1 MOI30% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5047Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay1 MOI30% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5048Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay10 MOI20% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5049Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay0.1 MOI30% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5050Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay1 MOI30% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5051Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay10 MOI20% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5377Maraba virusMG1RNARhabdoviridaeNoneYesNoNoATCCHuman triple negative breast cancer cell lineMDA-MB-231NANACoomassie brilinat blue staining4 micromolar80% cell viable after 48 hoursNoNoNA No responseNAInduction of apoptosisNAIn clinical trial for various cancer cell line27503504
OV_5380Maraba virusMG1RNARhabdoviridaeNoneNoVirus in combination with 2 micromolar palcitaxel for 48 hoursNoATCCHuman triple negative breast cancer cell lineMDA-MB-231NANACoomassie brilinat blue staining4 micromolar30% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisLevel of IFN beta production does not effected by combinationIn clinical trial for various cancer cell line27503504