Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 26. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1443	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	XTT assay	Log10 pfu/cell	20% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1452	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus strain in combination with palcitaxel (100 micromolar)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	Dose response analysis curve	Log10 pfu/cell	100% cell death after 4 days	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1453	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.003 +/- 0.001 micromolar, 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.903 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1459	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.003 +/- 0.001 micromolar, 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.221	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1465	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.003 +/- 0.001 micromolar, 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.057	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1471	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.003 +/- 0.001 micromolar, 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.193 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1477	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.003 +/- 0.001 micromolar, 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.042	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1483	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.003 +/- 0.001 micromolar, 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.013	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1489	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (5.31+/-1.21, ratio is 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.875	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1495	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (5.31+/-1.21, ratio is 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.313	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1501	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (5.31+/-1.21, ratio is 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.112	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1507	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (5.31+/-1.21, ratio is 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.061	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1513	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (5.31+/-1.21, ratio is 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.006	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1519	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (5.31+/-1.21, ratio is 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.129	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1525	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.01+/- 0.003, 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.199	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1531	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.01+/- 0.003, 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75 % cell death at CI 0.126	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1537	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.01+/- 0.003, 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.126	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1543	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.01+/- 0.003, 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.006	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1549	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.01+/- 0.003, 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.017	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1555	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.01+/- 0.003, 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.054	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1561	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(0.92+/-0.35nm, 1:5.3)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.255	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1567	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(0.92+/-0.35nm, 1:5.3)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.149	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1573	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(0.92+/-0.35nm, 1:5.3)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.089	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1579	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(0.92+/-0.35nm, 1:53.3)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.069	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1585	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(0.92+/-0.35nm, 1:53.3)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.045	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1591	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(0.92+/-0.35nm, 1:53.3)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.031	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950