Browse By Cell Line Result Page of OvirusTdb
The total number of records retrieved from this search are 41. Click on ID to see further detail.
IDOV_1139 | Virus nameHerpes simplex virus | Virus strainMutant | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationMutant for gamma 34.5, lacZ and alpha 47 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01MOI | In-vitro resultKill cancer cell line after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID16278413 |
IDOV_1140 | Virus nameHerpes simplex virus | Virus strainMutant | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationMutant for gamma 34.5, lacZ and alpha 47 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1MOI | In-vitro resultKill cancer cell line after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID16278413 |
IDOV_1262 | Virus nameAdenovirus | Virus strainAxdAdb-3 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDouble mutated for E1A and E1B gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineProstate cancer cell line | Cell lineLNCaP | Concentration of cell line3.0E+3 cells per well | In-vitro toxicity | AssayMTT assay | In-vitro virus concentration30 MOI | In-vitro resultSurviving cell number reached to 1000 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18063085 |
IDOV_1278 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration0.1 MOI | In-vitro result98% cell viablity after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1279 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration0.1 MOI | In-vitro result90% cell viablity after day 2 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1280 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration0.1 MOI | In-vitro result70% cell viabilty after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1281 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration0.1 MOI | In-vitro result20% cell viability after day 4 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1282 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration1 MOI | In-vitro result100% cell viability after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1283 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration1 MOI | In-vitro result70 % cell viability after day 2 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1284 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration1 MOI | In-vitro result20% cell viability after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1285 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration1 MOI | In-vitro result20% cell viability after day 4 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1286 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration10 MOI | In-vitro result80% cell viability after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1287 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration10 MOI | In-vitro result50% cell viability after day 2 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1288 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_1289 | Virus nameAdenovirus | Virus strainOBP-301 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line1000 cells per well | In-vitro toxicityNA | AssayCell proliferation kit by Roche Diagnostics | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after day 4 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18274558 |
IDOV_2018 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.1 MOI | In-vitro result90% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2019 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result60% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2020 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration10 MOI | In-vitro result20% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2021 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration100 MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2031 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (7.5 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.125 MOI | In-vitro result70% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2032 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (15 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.25 MOI | In-vitro result70% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2033 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (30 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.5 MOI | In-vitro result60% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2034 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (60 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result50% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2035 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (120 nM) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line7.5E+3 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration2 MOI | In-vitro result40% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_2046 | Virus nameReovirus | Virus strainReovirus T3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with Docetaxel (5 mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismMice injected with PC3 cell line | In-vivo virus concentration1.0E+8 pfu | In-vivo toxicityNA | In-vivo resultReduction in tumor volume after day 15 | Mode of deliveryIntratumoral | Pathway inducedVirus cause increase in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21645351 |
IDOV_3171 | Virus nameSemliki forest virus | Virus strainSFV-VA7 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line40000 cells per well | In-vitro toxicityNA | AssayCalcein AM assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28557974 |
IDOV_3172 | Virus nameSemliki forest virus | Virus strainSFV-VA7 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line40000 cells per well | In-vitro toxicityNA | AssayCalcein AM assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28557974 |
IDOV_3173 | Virus nameSemliki forest virus | Virus strainSFV-VA7 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line40000 cells per well | In-vitro toxicityNA | AssayCalcein AM assay | In-vitro virus concentration1 MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28557974 |
IDOV_3174 | Virus nameSemliki forest virus | Virus strainSFV-VA7 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line40000 cells per well | In-vitro toxicityNA | AssayCalcein AM assay | In-vitro virus concentration10 MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28557974 |
IDOV_3175 | Virus nameSemliki forest virus | Virus strainSFV-VA7 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismCAnM.Cg-Foxn1nu/Crl Balb/c nude mice subcutaneous xenograft for LNCaP (5.0E+6) | In-vivo virus concentration1.0E+6 pfu | In-vivo toxicityNA | In-vivo resultComplete regression in tumor volume after 20 days | Mode of deliveryIntraperitoneal | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28557974 |
IDOV_3176 | Virus nameSemliki forest virus | Virus strainSFV-VA7 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismCAnM.Cg-Foxn1nu/Crl Balb/c nude mice subcutaneous xenograft for LNCaP (5.0E+6) | In-vivo virus concentration1.0E+6 pfu | In-vivo toxicityNA | In-vivo resultComplete regression in tumor volume after 20 days | Mode of deliveryIntraperitoneal | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28557974 |
IDOV_3530 | Virus nameAdenovirus | Virus strainAdenovirus ZD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion in E1B55 viral protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result60% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3531 | Virus nameAdenovirus | Virus strainAdenovirus ZD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion in E1B55 viral protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result45% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3532 | Virus nameAdenovirus | Virus strainAdenovirus ZD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion in E1B55 viral protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3533 | Virus nameAdenovirus | Virus strainAdenovirus ZD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion in E1B55 viral protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration20 MOI | In-vitro result18% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3534 | Virus nameAdenovirus | Virus strainAdenovirus GD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationGOLPH2 regulated aoncolytic adenovirus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result45% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3535 | Virus nameAdenovirus | Virus strainAdenovirus GD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationGOLPH2 regulated aoncolytic adenovirus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result20% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3536 | Virus nameAdenovirus | Virus strainAdenovirus GD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationGOLPH2 regulated aoncolytic adenovirus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3537 | Virus nameAdenovirus | Virus strainAdenovirus GD55 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationGOLPH2 regulated aoncolytic adenovirus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration20 MOI | In-vitro result15% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID28880012 |
IDOV_3726 | Virus nameVesicular stomatitis virus | Virus strainVSV-GP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationvirus expressing GP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell lineNA | In-vitro toxicityNA | AssayAbsorbance measurements | In-vitro virus concentration0.1 MOI | In-vitro result70% cell viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryVirus induce apoptosis in cancer cell | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID29696636 |
IDOV_3733 | Virus nameVesicular stomatitis virus | Virus strainVSV-GP | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationvirus expressing GP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell lineLNCaP | Concentration of cell lineNA | In-vitro toxicityNA | AssayAbsorbance measurements | In-vitro virus concentration10 MOI | In-vitro result15% cell viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryVirus induce apoptosis in cancer cell | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID29696636 |