Detailed description page of Selected OV_ID


OV_3176 details
Primary information
OV_IDOV_3176
Virus Name Semliki forest virus
StrainSFV-VA7
Virus typeRNA
Virus familyTogaviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman prostate cancer cell line
Cell lineLNCaP
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismCAnM.Cg-Foxn1nu/Crl Balb/c nude mice orthotopic for LNCaP (5 × 10⁵)
In-vivo virus concentration1 × 10⁶ pfu
In-vivo toxicityNA
In-vivo resultComplete regression in tumor volume after 20 days
Mode of deliveryIntraperitoneal
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID28557974