Detailed description page of Selected OV_ID


OV_1140 details
Primary information
OV_IDOV_1140
Virus Name Herpes simplex virus
StrainMutant
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeMutant for gamma 34.5, lacZ and alpha 47 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman prostate cancer cell line
Cell lineLNCaP
Concentration of cell line3
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration0.1MOI
In-vitro resultKill cancer cell line after 3 days
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID16278413