Primary information |
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OV_ID | OV_1140 |
Virus Name | Herpes simplex virus |
Strain | Mutant |
Virus type | DNA |
Virus family | Herpesviridae |
Modification in virus genome | Mutant for gamma 34.5, lacZ and alpha 47 gene |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | ATCC |
Origin of cell line | Human prostate cancer cell line |
Cell line | LNCaP |
Concentration of cell line | 3 |
In-vitro toxicity | NA |
Assay | MTT assay |
In-vitro virus concentration | 0.1MOI |
In-vitro result | Kill cancer cell line after 3 days |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | NA |
Immunogenic effect | NA |
Clinical trial | NA |
PMID | 16278413 |