The total number of records retrieved from this search are 58. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_2977	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human neck and squamous carcinoma cell line	SCC-9	7.68E+3 cells per well	NA	Alamar blue assay	2.4 × 10⁸ pfu	33.2 +/- 9.9% cell viable after 96 hours	No	No	NA	No response	NA	NA	NA	NA	25890191
OV_2978	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human neck and squamous carcinoma cell line	SCC-25	7.68E+3 cells per well	NA	Alamar blue assay	2.4 × 10⁸ pfu	54.6 +/- 21.5% cell viable after 96 hours	No	No	NA	No response	NA	NA	NA	NA	25890191
OV_2979	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human neck and squamous carcinoma cell line	UM-SCC-38	7.68E+3 cells per well	NA	Alamar blue assay	2.4 × 10⁸ pfu	83.9 +/- 16.3% cell viable after 96 hours	No	No	NA	No response	NA	NA	NA	NA	25890191
OV_2980	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human neck and squamous carcinoma cell line	UM-SCC-47	7.68E+3 cells per well	NA	Alamar blue assay	2.4 × 10⁸ pfu	97.2 +/- 4.7% cell viable after 96 hours	No	No	NA	No response	NA	NA	NA	NA	25890191
OV_2981	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human neck and squamous carcinoma cell line	UM-SCC-104	7.68E+3 cells per well	NA	Alamar blue assay	2.4 × 10⁸ pfu	82.3 +/- 6.5% cell viable after 96 hours	No	No	NA	No response	NA	NA	NA	NA	25890191
OV_3066	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	18% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3067	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	1% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3068	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3096	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	18% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3097	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	2% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3098	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3115	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	No	Virus strain in combination with 5-FC (200mg/kg)	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	NA	NA	NA	NA	NA	BD62 mice xenograft for Lovo cell line	1.0E+7 pfu	NA	Tumor volume decreases to below 100 mm after 50 days	Intravenous	NA	NA	NA	31011628
OV_3116	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	No	Virus strain in combination with 5-FC (200mg/kg)	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	NA	NA	NA	NA	NA	BD62 mice xenograft for Lovo cell line	1.0E+7 pfu	NA	Tumor volume decreases to below 100 mm after 50 days	Intravenous	NA	NA	NA	31011628
OV_4401	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Statistical method	16.64+/- 1.41	20% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4402	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Statistical method	57.46+/- 8.37	50% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4403	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Statistical method	96.31+/- 10.76	70% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4404	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a/carbo-15a	NA	NA	Statistical method	16.56+/- 2.78	20% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4405	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a/carbo-15a	NA	NA	Statistical method	52.17+/- 9.68	50% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4406	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a/carbo-15a	NA	NA	Statistical method	90.13+/- 14.42	70% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4416	Adenovirus	ONYX-015	DNA	Adenoviridae	None	No	Virus in combination with melphalan (2.5 microgram)	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Flow cytometry	20 pfu	3% cancer cell death after day 3	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4417	Adenovirus	ONYX-015	DNA	Adenoviridae	None	No	Virus in combination with melphalan (5 microgram)	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Flow cytometry	20 pfu	6% cancer cell death after day 3	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4418	Adenovirus	ONYX-015	DNA	Adenoviridae	None	No	Virus in combination with melphalan (7.5 microgram)	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Flow cytometry	20 pfu	10% cancer cell death after day 3	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4419	Adenovirus	ONYX-015	DNA	Adenoviridae	None	No	Virus in combination with melphalan (2.5 microgram)	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Flow cytometry	20 pfu	3% cancer cell death after day 3	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4420	Adenovirus	ONYX-015	DNA	Adenoviridae	None	No	Virus in combination with melphalan (5 microgram)	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Flow cytometry	20 pfu	15% cancer cell death after day 3	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4421	Adenovirus	ONYX-015	DNA	Adenoviridae	None	No	Virus in combination with melphalan (7.5 microgram)	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Flow cytometry	20 pfu	25% cancer cell death after day 3	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4607	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	1 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4608	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	10 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4609	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	100 VP per cell	70% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4610	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	1 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4611	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	10 VP per cell	50% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4612	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	100 VP per cell	10% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4613	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	1 VP per cell	70% cell viablity after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4614	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	10 VP per cell	58 cell viablity after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4615	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	100 VP per cell	10% cell viablity after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4616	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	1 VP per cell	100% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4617	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	10 VP per cell	100% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4618	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	100 VP per cell	100% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4619	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	1 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4620	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	10 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4621	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	100 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4622	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	1 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4623	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	10 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4624	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	100 VP per cell	40% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4625	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	1 VP per cell	80% cell viablity after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4626	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	10 VP per cell	80% cell viablity after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4627	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	100 VP per cell	70% cell viablity after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4628	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	1 VP per cell	100% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4629	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	10 VP per cell	100% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4630	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	100 VP per cell	100% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_5626	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human head and neck carcinoma cell line	KB	80% confluency	NA	MTT assay	4 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5846	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human head and neck carcinoma cell line	KB	80% confluency	NA	NA	4 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5847	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human head and neck carcinoma cell line	A253	80% confluency	NA	NA	2.7 ×10³ pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5848	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human head and neck carcinoma cell line	FaDu	80% confluency	NA	NA	2.9 ×10³ pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5849	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human head and neck carcinoma cell line	Hep-2	80% confluency	NA	NA	1.5 ×10⁴ pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5906	Newcastle disease virus	NDV-B1	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human neck and head carcinoma cell line	SCC	5E+5 pfu	NA	LDH release assay	0.1 MOI	60% cell killing after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5907	Newcastle disease virus	NDV-B1	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human neck and head carcinoma cell line	SCC	5E+5 pfu	NA	LDH release assay	0.1 MOI	No cell death observed after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5908	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	ATCC	Human neck and head carcinoma cell line	SCC	5E+5 pfu	NA	LDH release assay	0.1 MOI	100% cell killing observed after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5909	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	ATCC	Human neck and head carcinoma cell line	SCC	5E+5 pfu	NA	LDH release assay	0.1 MOI	70% cell killing after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984