Detailed description page of Selected OV_ID


OV_4416 details
Primary information
OV_IDOV_4416
Virus Name Adenovirus
StrainONYX-015
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeNone
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with melphalan (2.5 microgram)
Immune gene induction in virus genomeNo
Source of cell lineSt. Joseph healthcare, London
Origin of cell lineHuman head and neck squamous cell carcinoma
Cell lineHN-5a
Concentration of cell line0
In-vitro toxicityNA
AssayFlow cytometry
In-vitro virus concentration20 pfu
In-vitro result3% cancer cell death after day 3
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionIncrease in apoptosis upto 25%
Immunogenic effectNA
Clinical trialNA
PMID26429639