Browse By Assay Result Page of OvirusTdb

The total number record retrieved from this search are 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_753AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman chronic myelogenous leukemic cell lineK5621.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI90% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_754AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman chronic myelogenous leukemic cell lineK5621.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI58% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_755AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman chronic myelogenous leukemic cell lineK5621.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI41% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_756AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman chronic myelogenous leukemic cell lineK5621.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI36% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_757AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman chronic myelogenous leukemic cell lineK5621.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI25% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_758AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman megakaryoblastic leukemic cell lineMEG-011.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI90% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_759AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman megakaryoblastic leukemic cell lineMEG-011.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI60% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_760AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman megakaryoblastic leukemic cell lineMEG-011.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI49% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_761AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman megakaryoblastic leukemic cell lineMEG-011.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI36% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_762AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman megakaryoblastic leukemic cell lineMEG-011.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI30% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_763AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineNB41.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI99% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_764AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineNB41.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI76% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_765AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineNB41.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI64% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_766AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineNB41.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI60% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_767AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineNB41.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI52% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_768AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineHL-601.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI80% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_769AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineHL-601.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI60% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_770AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineHL-601.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI50% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_771AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineHL-601.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI46% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_772AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineHL-601.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI40% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_773AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI80% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_774AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI65% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_775AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI55% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_776AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI46% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_777AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI39% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_778AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI88% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_779AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI60% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_780AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI50% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_781AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI39% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_782AdenovirusSG611DNAAdenoviridaeNoneYesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI38% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_783AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman chronic myelogenous leukemic cell lineK5621.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI90% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_784AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman chronic myelogenous leukemic cell lineK5621.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI57% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_785AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman chronic myelogenous leukemic cell lineK5621.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI30% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_786AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman chronic myelogenous leukemic cell lineK5621.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI11% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_787AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman chronic myelogenous leukemic cell lineK5621.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI9% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_788AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman megakaryoblastic leukemic cell lineMEG-011.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI90% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_789AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman megakaryoblastic leukemic cell lineMEG-011.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI45% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_790AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman megakaryoblastic leukemic cell lineMEG-011.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI34% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_791AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman megakaryoblastic leukemic cell lineMEG-011.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI11% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_792AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman megakaryoblastic leukemic cell lineMEG-011.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI8% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_793AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineNB41.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI99% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_794AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineNB41.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI60% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_795AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineNB41.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI49% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_796AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineNB41.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI35% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_797AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineNB41.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI30% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_798AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineHL-601.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI80% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_799AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineHL-601.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI40% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_800AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineHL-601.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI32% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_801AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineHL-601.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI25% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_802AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineHL-601.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI20% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_803AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI80% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_804AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI56% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_805AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI34% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_806AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI21% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_807AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI18% cancer cell viability at 120 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_808AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI90% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_809AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI50% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_810AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI39% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_811AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay120 MOI21% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_812AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1YesNoNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineBV-1731.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay160 MOI18% cancer cell viability at 96 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_813AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 40 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman chronic myelogenous leukemic cell lineK5621.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI50% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_814AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 120 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman chronic myelogenous leukemic cell lineK5621.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI42% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_815AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 40 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI64% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_816AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 120 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI50% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_817AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 120 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman megakaryoblastic leukemic cell lineMEG-011.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI80% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_818AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 240 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman megakaryoblastic leukemic cell lineMEG-011.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI76% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_819AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 120 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineNB41.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI64% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_820AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 240 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineNB41.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay10 MOI55% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_821AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 40 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman chronic myelogenous leukemic cell lineK5621.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI35% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_822AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 120 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman chronic myelogenous leukemic cell lineK5621.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI29% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_823AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 40 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI50% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_824AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 120 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute lymphoblastic leukemic cell lineSUP-B151.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay80 MOI38% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_825AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 120 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman megakaryoblastic leukemic cell lineMEG-011.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI40% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_826AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 240 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman megakaryoblastic leukemic cell lineMEG-011.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI39% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_827AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 120 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineNB41.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI50% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_828AdenovirusSG611-VSTM1DNAAdenoviridaeA VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1NoViral strain in combination with DNR 240 ng/mlNoGibco, Thermo Fisher Scientific, Waltham, MA, USAHuman acute promyelocytic leukemic cell lineNB41.0E+4 cells per wellSlight toxicity to L-02 and BJ cell lineCell counting kit-8 (CCK-8) assay40 MOI42% cancer cell viability at 72 hoursNoNoNA No responseNAEnhanced apoptosis activation is observedNANA27472927
OV_2806AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (1.5 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMCF-72000 cells per wellNACell counting kit-80.25 MOI50% cells viabilityNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2807AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (3 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMCF-72000 cells per wellNACell counting kit-80.5 MOI40% cells are viableNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2808AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (4.5 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMCF-72000 cells per wellNACell counting kit-80.75 MOI30% cells are viableNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2809AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (4 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMDA-MB-4682000 cells per wellNACell counting kit-81 MOI20% cells viabilityNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2810AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (8 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMDA-MB-4682000 cells per wellNACell counting kit-82 MOI18% cells are viableNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2811AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (16 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMDA-MB-4682000 cells per wellNACell counting kit-84 MOI10% cells are viableNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_3141Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay5 MOI50% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3142Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI25% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3143Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay20 MOI18% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3144Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay5 MOI50% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3145Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay10 MOI30% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3146Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay20 MOI25% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3147Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI90% cell viability after day 1NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3148Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI60% cell viability after day 2NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3149Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI40% cell viability after day 3NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3150Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI10% cell viability after day 4NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3151Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay10 MOI90% cell viability after day 1NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3152Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay10 MOI80% cell viability after day 2NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3153Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay10 MOI70% cell viability after day 3NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3154Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay10 MOI40% cell viability after day 4NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3157Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneNoVirus in combination with rapamycin (5nM)NoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay5 MOI60% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3158Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneNoVirus in combination with rapamycin (10nM)NoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI50% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3159Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneNoVirus in combination with rapamycin (20nM)NoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay20 MOI40% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3160Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneNoVirus in combination with rapamycin (5nM)NoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay5 MOI70% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127