Detailed description page of Selected OV_ID


OV_3152 details
Primary information
OV_IDOV_3152
Virus Name Herpes simplex virus
StrainSPDD-UG
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeVirus expressing SNORD44 gene and GAS5 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineCell bank of type culture collection of chinese academy of science
Origin of cell lineHuman colon carcinoma cell line
Cell lineLS174T
Concentration of cell line2000
In-vitro toxicityNA
AssayCCK-8 assay
In-vitro virus concentration10 MOI
In-vitro result80% cell viability after day 2
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionCaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell line
Immunogenic effectNA
Clinical trialNA
PMID28530127