Browse result page of ImmunoSPdb

The total number entries retrieved from this search are 23
IDNameSequenceLengthChiralityN-Terminal ModificationC-Terminal ModificationChemical ModificationLinear/CyclicNatureSourceTargetMechanism of ActionIn vivo/ In vitroCell LineIC-50In vivo ModelAssay TypeLethal DoseCombination TherapyPubmed IDYear of Publication
1138VIVIT (fused with GST)VIVIT5LNoneNoneNoneLinearSyntheticNANFATInhibits NFAT activationIn vitroCOS7 cells, HeLa cells, BHK cells, and NIH3T3 cellsNAHippocampal primary neurons of ratNANAfused with GST127630352003
1211NAHAwY4MixNoneNoneA-D-Glu or D-iGlu, Y-OH or a substituted amide(C1-C3)LinearNaturalTotal tissue extractsBone marrow cells, Hematopoietic progenitor cellsReduces amount of ekzokolony cells, reduce KOE-C pool sizesBothHematopoietic progenitor Cells from miceNAMiceNANANARU2123859 (C1)1998
1269Copolymer 1(Cop 1)EKAY4LNoneNoneNoneLinearSyntheticNA (Random copolymer)T-cellsInhibits T cell proliferation in response to graft cells, preventing the secretion of cytokines like interleukin 2 (IL-2) and interferon γ (IFN-γ)In vivoNANABALB/c mice, Lewis ratsSkin Grafts Transplantation, Thyroid graft TransplantationNACopolymer 1-related heteropolymers in combination with other immunosuppressive drugs induce a synergistic effect, This is used as copolymer or related hateropolymerUS 20060276390 A12006
1270Copolymer 1(Cop 1)ekay4DNoneNoneNoneLinearSyntheticNA (Random copolymer)T-cellsInhibits T cell proliferation in response to graft cells, preventing the secretion of cytokines like interleukin 2 (IL-2) and interferon γ (IFN-γ)In vivoNANABALB/c mice, Lewis ratsSkin Grafts Transplantation, Thyroid graft TransplantationNACopolymer 1-related heteropolymers in combination with other immunosuppressive drugs induce a synergistic effect, This is used as copolymer or related hateropolymerUS 20060276390 A12006
1271Copolymer 1(Cop 1)EKAY4MixNoneNoneNoneLinearSyntheticNA (Random copolymer)T-cellsInhibits T cell proliferation in response to graft cells, preventing the secretion of cytokines like interleukin 2 (IL-2) and interferon γ (IFN-γ)In vivoNANABALB/c mice, Lewis ratsSkin Grafts Transplantation, Thyroid graft TransplantationNACopolymer 1-related heteropolymers in combination with other immunosuppressive drugs induce a synergistic effect, This is used as copolymer or related hateropolymerUS 20060276390 A12006
1339Formula 1RK(Chc)DV4LNoneNoneChc addition at LysineLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1340Formula 2RK(Chc)D3LNoneNoneChc addition at LysineLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1341Formula 3R-Sar-DV4LNoneNoneSar = N-Methylglycine (aka sarcosine)LinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1342Formula 4R-Sar-D3LNoneNoneSar = N-Methylglycine (aka sarcosine)LinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1343Formula 5Orn-KDV4LNoneNoneOrn = OrnithineLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1344Formula 6Orn-KD3LNoneNoneOrn = OrnithineLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1345Formula 7RK-Aad-V4LNoneNoneAad = 3-Aminoadipic acidLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1346Formula 8RK-Aad3LNoneNoneAad = 3-Aminoadipic acidLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1351Formula 13KSKL4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1352Formula 14SKL3LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1353Formula 15SSST4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1354Formula 16LET3LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1355Formula 17LTET4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1356Formula 18PKLT4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1357Formula 19KKTE4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1358Formula 20KHL3LNoneAmidationNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1436iDDiGlu-w2DNoneNoneiGlu = iso glutamic acidLinearSyntheticNot mentionedNAInhibits cell proliferationIn vivoNoneNAMice spleen cellsThymidine suicide test0.02μg/mlNAUS 6410515 B12002
1437Noneew2DNoneNoneNoneLinearSyntheticNot mentionedNAInhibits cell proliferationIn vivoNoneNAMice spleen cellsThymidine suicide test0.02μg/mlNAUS 6410515 B12002