1138 | VIVIT (fused with GST) | VIVIT | 5 | L | None | None | None | Linear | Synthetic | NA | NFAT | Inhibits NFAT activation | In vitro | COS7 cells, HeLa cells, BHK cells, and NIH3T3 cells | NA | Hippocampal primary neurons of rat | NA | NA | fused with GST | 12763035 | 2003 |
1211 | NA | HAwY | 4 | Mix | None | None | A-D-Glu or D-iGlu, Y-OH or a substituted amide(C1-C3) | Linear | Natural | Total tissue extracts | Bone marrow cells, Hematopoietic progenitor cells | Reduces amount of ekzokolony cells, reduce KOE-C pool sizes | Both | Hematopoietic progenitor Cells from mice | NA | Mice | NA | NA | NA | RU2123859 (C1) | 1998 |
1269 | Copolymer 1(Cop 1) | EKAY | 4 | L | None | None | None | Linear | Synthetic | NA (Random copolymer) | T-cells | Inhibits T cell proliferation in response to graft cells, preventing the secretion of cytokines like interleukin 2 (IL-2) and interferon γ (IFN-γ) | In vivo | NA | NA | BALB/c mice, Lewis rats | Skin Grafts Transplantation, Thyroid graft Transplantation | NA | Copolymer 1-related heteropolymers in combination with other immunosuppressive drugs induce a synergistic effect, This is used as copolymer or related hateropolymer | US 20060276390 A1 | 2006 |
1270 | Copolymer 1(Cop 1) | ekay | 4 | D | None | None | None | Linear | Synthetic | NA (Random copolymer) | T-cells | Inhibits T cell proliferation in response to graft cells, preventing the secretion of cytokines like interleukin 2 (IL-2) and interferon γ (IFN-γ) | In vivo | NA | NA | BALB/c mice, Lewis rats | Skin Grafts Transplantation, Thyroid graft Transplantation | NA | Copolymer 1-related heteropolymers in combination with other immunosuppressive drugs induce a synergistic effect, This is used as copolymer or related hateropolymer | US 20060276390 A1 | 2006 |
1271 | Copolymer 1(Cop 1) | EKAY | 4 | Mix | None | None | None | Linear | Synthetic | NA (Random copolymer) | T-cells | Inhibits T cell proliferation in response to graft cells, preventing the secretion of cytokines like interleukin 2 (IL-2) and interferon γ (IFN-γ) | In vivo | NA | NA | BALB/c mice, Lewis rats | Skin Grafts Transplantation, Thyroid graft Transplantation | NA | Copolymer 1-related heteropolymers in combination with other immunosuppressive drugs induce a synergistic effect, This is used as copolymer or related hateropolymer | US 20060276390 A1 | 2006 |
1339 | Formula 1 | RK(Chc)DV | 4 | L | None | None | Chc addition at Lysine | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1340 | Formula 2 | RK(Chc)D | 3 | L | None | None | Chc addition at Lysine | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1341 | Formula 3 | R-Sar-DV | 4 | L | None | None | Sar = N-Methylglycine (aka sarcosine) | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1342 | Formula 4 | R-Sar-D | 3 | L | None | None | Sar = N-Methylglycine (aka sarcosine) | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1343 | Formula 5 | Orn-KDV | 4 | L | None | None | Orn = Ornithine | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1344 | Formula 6 | Orn-KD | 3 | L | None | None | Orn = Ornithine | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1345 | Formula 7 | RK-Aad-V | 4 | L | None | None | Aad = 3-Aminoadipic acid | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1346 | Formula 8 | RK-Aad | 3 | L | None | None | Aad = 3-Aminoadipic acid | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1351 | Formula 13 | KSKL | 4 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1352 | Formula 14 | SKL | 3 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1353 | Formula 15 | SSST | 4 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1354 | Formula 16 | LET | 3 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1355 | Formula 17 | LTET | 4 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1356 | Formula 18 | PKLT | 4 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1357 | Formula 19 | KKTE | 4 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1358 | Formula 20 | KHL | 3 | L | None | Amidation | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1436 | iDD | iGlu-w | 2 | D | None | None | iGlu = iso glutamic acid | Linear | Synthetic | Not mentioned | NA | Inhibits cell proliferation | In vivo | None | NA | Mice spleen cells | Thymidine suicide test | 0.02μg/ml | NA | US 6410515 B1 | 2002 |
1437 | None | ew | 2 | D | None | None | None | Linear | Synthetic | Not mentioned | NA | Inhibits cell proliferation | In vivo | None | NA | Mice spleen cells | Thymidine suicide test | 0.02μg/ml | NA | US 6410515 B1 | 2002 |