Browse result page of ImmunoSPdb

The total number entries retrieved from this search are 6
IDNameSequenceLengthChiralityN-Terminal ModificationC-Terminal ModificationChemical ModificationLinear/CyclicNatureSourceTargetMechanism of ActionIn vivo/ In vitroCell LineIC-50In vivo ModelAssay TypeLethal DoseCombination TherapyPubmed IDYear of Publication
1042ISP region (Mutant D105)EVVLQNRRGLDLLTAEQGGICLALQEKCCFYANKS35LNoneNoneNoneLinearProtein DerivedWithin the transmembrane (TM) protein of Mason-Pfizer monkey virusT-cell and B-cellImmunosuppressive effect on both T-cell and B-cell mitogenic responseIn vitroHeLa, COS-1, CV-1and BHK cellsNANANANANA13164621992
1043ISP region (Mutant D33)LQNRRGLDLLT11LNoneNoneNoneLinearProtein DerivedWithin the transmembrane (TM) protein of Mason-Pfizer monkey virusT-cell and B-cellImmunosuppressive effect on both T-cell and B-cell mitogenic responseIn vitroHeLa, COS-1, CV-1and BHK cellsNANANANANA13164621992
1268NACVCVCLLPRYPSAGVFTYLNTKIITFDSVLSCA33LNoneNoneNoneLinearProtein DerivedAmino acid sequences derived from a human native nucleotide sequence capable of expressing GIF (glycosylation-inhibiting factors)B-cellsGlycosylation inhibiting factor activity causing the suppression of immunoglobulin E (IgE) productionIn vitroMesenteric lymph node (MLN) cellsNALewis RatRosette inhibition assay, tests of the IgE-SF activityNANAEP 0255394 A21987
1371A2.94-112TLQRMYGCDVGSDWRFLRG19LNoneNoneNoneLinearProtein Derivedα2 domain of HLA-A2B-Lymphoblastoid cells (B-cell)Inhibit by binding to variable T cell receptorIn vitroAJY CTL cell lineNANoneHummoral Immune Response assayNANAUS 58885121999
1372A2.98-113MYGCDVGSDWRFLRGY16LNoneNoneNoneLinearProtein Derivedα2 domain of HLA-A2B-Lymphoblastoid cells (B-cell)Inhibit by binding to variable T cell receptorIn vitroAJY CTL cell lineNANoneHummoral Immune Response assayNANAUS 58885121999
1373A2.101-108CDVGSDWR8LNoneNoneNoneLinearProtein Derivedα2 domain of HLA-A2B-Lymphoblastoid cells (B-cell)Inhibit by binding to variable T cell receptorIn vitroJY cells (HKA-A2, B7, DR4,6)NANoneHummoral Immune Response assayNANAUS 58885121999