Browse result page of ImmunoSPdb

The total number entries retrieved from this search are 28
IDNameSequenceLengthChiralityN-Terminal ModificationC-Terminal ModificationChemical ModificationLinear/CyclicNatureSourceTargetMechanism of ActionIn vivo/ In vitroCell LineIC-50In vivo ModelAssay TypeLethal DoseCombination TherapyPubmed IDYear of Publication
1071Cycloamanide CLPMLGFLV8LNoneNoneR and S sulfoxide on methionineCyclicNaturalIsolated from the mushroom Amanita phalloidesNANot investigatedBothSRBC (sheep red blood cells)NACBA/Iiw mice 8-10 weeksHumoral immune response test,PFC (plaque froming cell) test, DTH (delayed type hypersensitivity) testNANA84417061992
1072Cycloamanide DLPMLGFLP8LNoneNoneR and S sulfoxide on methionineCyclicNaturalIsolated from the mushroom Amanita phalloidesNANot investigatedBothSRBC (sheep red blood cells)NACBA/Iiw mice 8-10 weeksHumoral immune response test,PFC (plaque froming cell) test, DTH (delayed type hypersensitivity) testNANA84417061992
1121Charybdotoxin (Venom peptide)XFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS37LNoneNoneX=PyroGlutamic acidLinearNaturalLeiurus quinquestriatus hebraeus (scorpion)K+ (potassium) channelPotassium channel blockerIn vitroNANANANANANA243331932014
1125Iberiotoxin (Venom peptide)XFTDVDCSVSKECWSVCKDLFGVDRGKCMGKKCRCYQ37LNoneNoneX=Pyroglutamic acid and disulfile linkage at Disulfide bridges: Cys7 - Cys28, Cys13 - Cys33, Cys17 - Cys35LinearNaturalButhus tamulus (scorpion)Blocker of several BK channelsBloackion channelsBothNANANANANANA243331932014
1202A1HS1II-Sta-PYVPL8LNoneNoneSta = (3S, 4S) -4- amino-3-hydroxy-6-methyl-heptanoic acid(C8H17NO3)CyclicSyntheticNALymphocytes, MacrophagesInfluence of phagocytic function of macrophages, and the retarding effect of the proliferation of LymphocytesBothSpleen LymphocyteNABALB / C miceDelayed-type hypersensitivity (DTH) test, Lymphocyte Proliferation test, MTTNACN 101289499 B2010
1212SEQ ID NO: 1ILAKFLHWL9LNoneNoneInventors midified C- or at the N-terminus of the peptides with stabilizing groups, groups for increasing the water solubility, luminescent markers, fluorescent markers, radioactive markers, metal markers, polymeric markers, antibodies, enzymes, epitope tags, amino acid, D- or L-amino acids, serine, glycine, aspartate, sugar groups, glucuronic acid, sulfate moieties and polyethylene glycol. for experimentsLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANADE 102006025146 A12007
1359CDP1GPRGP(HP)GP(HP)GPAGL(HP)GPK18LNoneNoneHP = HydroxyprolineLinearProtein DerivedCollagen derivedBystander antigensBy releasing transforming growth factor β (TGF-β)In vivoNoneNARatsNANANAUS 53993471995
1360CDP2GE(HP)GA(HP)GPAGP(HP)GE(HP)GA(HP)GPAG22LNoneNoneHP = HydroxyprolineLinearProtein DerivedCollagen derivedBystander antigensBy releasing transforming growth factor β (TGF-β)In vivoNoneNARatsNANANAUS 53993471995
1361CDP3GEEGLRGARGE(HP)GERGP(HP)GPQGAR24LNoneNoneHP = HydroxyprolineLinearProtein DerivedCollagen derivedBystander antigensBy releasing transforming growth factor β (TGF-β)In vivoNoneNARatsNANANAUS 53993471995
1362CDP2GE(HP)GA(HP)GPAGP(HP)GE(HP)GA(HP)GpAGp(HP)G25MixNoneNoneHP = HydroxyprolineLinearProtein DerivedCollagen derivedBystander antigensBy releasing transforming growth factor β (TGF-β)In vivoNoneNARatsNANANAUS 57209551998
1363CDP3GEEGLRGARGE(HP)GERGP(HP)GPQGA23LNoneNoneHP = HydroxyprolineLinearProtein DerivedCollagen derivedBystander antigensBy releasing transforming growth factor β (TGF-β)In vivoNoneNARatsNANANAUS 57209551998
1365CDP2GE(HP)GA(HP)GPAGP(HP)GE(HP)GA(HP)GPAGP(HP)G25LNoneNoneHP = HydroxyprolineLinearProtein DerivedCollagen derivedBystander antigensBy releasing transforming growth factor β (TGF-β)In vivoNoneNARatsNANANAUS 57831881998
1366CDP3GEEGLRGARGE(HP)GERGP(HP)GPQGAR24LNoneNoneHP = HydroxyprolineLinearProtein DerivedCollagen derivedBystander antigensBy releasing transforming growth factor β (TGF-β)In vivoNoneNARatsNANANAUS 57831881998
1368CDP2GE(HP)GA(HP)GPAGP(HP)GE(HP)GA(HP)GPAGP(HP)G25LNoneNoneHP = HydroxyprolineLinearProtein DerivedCollagen derivedBystander antigensBy releasing transforming growth factor β (TGF-β)In vivoNoneNARatsNANANAUS 58434451998
1369CDP3GEEGLRGARGE(HP)GERGP(HP)GPQGAR24LNoneNoneHP = HydroxyprolineLinearProtein DerivedCollagen derivedBystander antigensBy releasing transforming growth factor β (TGF-β)In vivoNoneNARatsNANANAUS 58434451998
1381SEQ ID8RSCIDTIPKSRCTAFQCKHSMKXYRLSFCRKTCGTC36LNoneNoneX = cyclohexylalanineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1382SEQ ID9RSCIDTIPKSRCTAFQCKHSMAYRLSXCRKTCGTC35LNoneNoneX = cyclohexylalanineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1392SEQ ID19RSCIDTIPKSQCTAFQCKHSXKYRLSFCRKTCGTC35LNoneNoneX = norleucine (nL)LinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1394SEQ ID21RSCIDTIPKSRCTAFQCKHSMXYRLSFCRKTCGTC35LNoneNoneX = norleucine (nL)LinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1395SEQ ID22RSCIDTIPKSRCTAFQCKHSMXYRLSFCRKTCGTC35LNoneNoneX = ornithineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1396SEQ ID23RSCIDTIPKSRCTAFQCKHSMXYRLSFCRKTCGTC35LNoneNoneX = homocitrullineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1399SEQ ID26RSCIDTIPKSRCTAFQCKHSMKXRLSFCRKTCGTC35LNoneNoneX = nitrophenylalanineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1400SEQ ID27RSCIDTIPKSRCTAFQCKHSMKXRLSFCRKTCGTC35LNoneNoneX = aminophenylalanineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1429SEQ ID56RSCIDTIPKSRCTAFQCKHSMXYRLSFCRKTCGTC35LNoneNoneX = diaminopropanoic acidLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1430SEQ ID57RSCIDTIPKSRCTAFQCKHSMKXRLSFCRKTCGTC35LNoneNoneX = benzoylphenylalanineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1431SEQ ID58XSCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneX = N-acetyl-arginineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1432SEQ ID59RSCIDTIPKSRCTAXQCKHSMKYRLSFCRKTCGTC35LNoneNoneX = azidophenylalanineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1494Glandular kallikrein (K1)VVGGYNXEMNSQPWQVAVYYFGEYLX26LNoneNoneX = not mentionedLinearNaturalSubmandibular glands of ratNative bovine type II collagenBy regulation function of Glandular KallikreinIn vivoNoneNASprague Dawley ratsHummoral Immune Response assayNANAUS 7195759 B22007