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Peptide Hormone

Search Result - 1

HMRbase accession number	10276
Swiss-prot Accession number	Q863C3 (Sequence in FASTA format)
Description	Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10) (GRP-(18-27))] (Fragment).
Source organism	Bos taurus (Bovine)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	126 Amino acids
Molecular weight	13840
References	1   Budipitojo T., Sasaki T., Cruzana M.B.C., Kitamura N., Yamada J.; "Molecular cloning of cDNA encoding an endometrial gastrin-releasingpeptide (GRP) of cow."; Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases. 2  PubMed abstract 2755876
Domain Name	Bombesin
Hormone Name	Neuromedin-C
Mature Hormone Sequence	GNHWAVGHLM
Position of mature hormone in Pre-Hormone protein	10 Residues from position (41-50)
Receptor	N/A
Gene ID	615323
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 2

HMRbase accession number	10336
Swiss-prot Accession number	Q8R1I2 (Sequence in FASTA format)
Description	Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)].
Source organism	Mus musculus (Mouse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear
Protein Length	146 Amino acids
Molecular weight	15659
References	1  PubMed abstract 16141072 2  PubMed abstract 15489334
Domain Name	Bombesin
Hormone Name	Gastrin-releasing peptide
Mature Hormone Sequence	APVSTGAGGGTVLAKMYPRGSHWAVGHLM
Position of mature hormone in Pre-Hormone protein	29 Residues from position (24-52)
Receptor	P21729    Detail in HMRbase
Gene ID	225642
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 3

HMRbase accession number	10337
Swiss-prot Accession number	Q8R1I2 (Sequence in FASTA format)
Description	Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)].
Source organism	Mus musculus (Mouse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	146 Amino acids
Molecular weight	15659
References	1  PubMed abstract 16141072 2  PubMed abstract 15489334
Domain Name	Bombesin
Hormone Name	Neuromedin-C
Mature Hormone Sequence	GSHWAVGHLM
Position of mature hormone in Pre-Hormone protein	10 Residues from position (43-52)
Receptor	P21729    Detail in HMRbase
Gene ID	225642
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 4

HMRbase accession number	11156
Swiss-prot Accession number	P29007 (Sequence in FASTA format)
Description	Gastrin-releasing peptide precursor (GRP-29) [Contains: Neuromedin-C(GRP-10); C-terminal extension peptide (CTEP)].
Source organism	Bombina orientalis (Oriental fire-bellied toad)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Archeobatrachia; Bombinatoridae; Bombina.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	Brain and stomach. In the stomach GRP was localized, at the base of the gastric pits, to occasional cells whose distribution and appearance were consistent with that of gut neuroendocrine cells
Post translational modification	N/A
Function	GRP stimulates gastrin release as well as other gastrointestinal hormones. May have a role as neurotransmitter or neuromodulator
Protein Length	155 Amino acids
Molecular weight	17813
References	1  PubMed abstract 1551901
Domain Name	Bombesin
Hormone Name	Gastrin-releasing peptide
Mature Hormone Sequence	SPTSQQHNDAASLSKIYPRGSHWAVGHLM
Position of mature hormone in Pre-Hormone protein	29 Residues from position (32-60)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 5

HMRbase accession number	11157
Swiss-prot Accession number	P29007 (Sequence in FASTA format)
Description	Gastrin-releasing peptide precursor (GRP-29) [Contains: Neuromedin-C(GRP-10); C-terminal extension peptide (CTEP)].
Source organism	Bombina orientalis (Oriental fire-bellied toad)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Archeobatrachia; Bombinatoridae; Bombina.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	Brain and stomach. In the stomach GRP was localized, at the base of the gastric pits, to occasional cells whose distribution and appearance were consistent with that of gut neuroendocrine cells
Post translational modification	N/A
Function	N/A
Protein Length	155 Amino acids
Molecular weight	17813
References	1  PubMed abstract 1551901
Domain Name	Bombesin
Hormone Name	Neuromedin-C
Mature Hormone Sequence	GSHWAVGHLM
Position of mature hormone in Pre-Hormone protein	10 Residues from position (51-60)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 6

HMRbase accession number	11158
Swiss-prot Accession number	Q863C3 (Sequence in FASTA format)
Description	Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10) (GRP-(18-27))] (Fragment).
Source organism	Bos taurus (Bovine)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	GRP stimulates gastrin release as well as other gastrointestinal hormones
Protein Length	126 Amino acids
Molecular weight	13840
References	1   Budipitojo T., Sasaki T., Cruzana M.B.C., Kitamura N., Yamada J.; "Molecular cloning of cDNA encoding an endometrial gastrin-releasingpeptide (GRP) of cow."; Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases. 2  PubMed abstract 2755876
Domain Name	Bombesin
Hormone Name	Gastrin-releasing peptide
Mature Hormone Sequence	APVTAGRGGALAKMYTRGNHWAVGHLM
Position of mature hormone in Pre-Hormone protein	27 Residues from position (24-50)
Receptor	N/A
Gene ID	615323
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 7

HMRbase accession number	11159
Swiss-prot Accession number	P47851 (Sequence in FASTA format)
Description	Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)].
Source organism	Ovis aries (Sheep)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear
Protein Length	134 Amino acids
Molecular weight	14855
References	1  PubMed abstract 7988429
Domain Name	Bombesin
Hormone Name	Gastrin-releasing peptide
Mature Hormone Sequence	APVTAGRAGALAKMYTRGNHWAVGHLM
Position of mature hormone in Pre-Hormone protein	27 Residues from position (24-50)
Receptor	N/A
Gene ID	443332
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 8

HMRbase accession number	11387
Swiss-prot Accession number	P07492 (Sequence in FASTA format)
Description	Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)].
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	GRP stimulates gastrin release as well as other gastrointestinal hormones
Protein Length	148 Amino acids
Molecular weight	16144
References	1  PubMed abstract 3001723 2  PubMed abstract 3211139 3  PubMed abstract 3003116 4  PubMed abstract 15489334
Domain Name	Bombesin
Hormone Name	Gastrin-releasing peptide
Mature Hormone Sequence	VPLPAGGGTVLTKMYPRGNHWAVGHLM
Position of mature hormone in Pre-Hormone protein	27 Residues from position (24-50)
Receptor	P30550    Detail in HMRbase
Gene ID	2922
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 9

HMRbase accession number	11388
Swiss-prot Accession number	P07492 (Sequence in FASTA format)
Description	Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)].
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	It is also a bombesin-like peptide, which causes potent stimulation of smooth muscle of uterus.
Protein Length	148 Amino acids
Molecular weight	16144
References	1  PubMed abstract 3001723 2  PubMed abstract 3211139 3  PubMed abstract 3003116 4  PubMed abstract 15489334
Domain Name	Bombesin
Hormone Name	Neuromedin-C
Mature Hormone Sequence	GNHWAVGHLM
Position of mature hormone in Pre-Hormone protein	10 Residues from position (41-50)
Receptor	P30550    Detail in HMRbase
Gene ID	2922
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 10

HMRbase accession number	11429
Swiss-prot Accession number	P24393 (Sequence in FASTA format)
Description	Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)].
Source organism	Rattus norvegicus (Rat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear
Protein Length	147 Amino acids
Molecular weight	15817
References	1  PubMed abstract 2843761
Domain Name	Bombesin
Hormone Name	Gastrin-releasing peptide
Mature Hormone Sequence	APVSTGAGGGTVLAKMYPRGSHWAVGHLM
Position of mature hormone in Pre-Hormone protein	29 Residues from position (24-52)
Receptor	P52500    Detail in HMRbase
Gene ID	171101
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 11

HMRbase accession number	11430
Swiss-prot Accession number	P24393 (Sequence in FASTA format)
Description	Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)].
Source organism	Rattus norvegicus (Rat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	147 Amino acids
Molecular weight	15817
References	1  PubMed abstract 2843761
Domain Name	Bombesin
Hormone Name	Neuromedin-C
Mature Hormone Sequence	GSHWAVGHLM
Position of mature hormone in Pre-Hormone protein	10 Residues from position (43-52)
Receptor	P52500    Detail in HMRbase
Gene ID	171101
PDB ID	N/A
Drugpedia	wiki
Comments