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Peptide Hormone

Search Result - 1

HMRbase accession number	10015
Swiss-prot Accession number	Q9PUR1 (Sequence in FASTA format)
Description	Glucagon-1 precursor [Contains: Glucagon-1 (Glucagon I); Glucagon-likepeptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I)].
Source organism	Petromyzon marinus (Sea lamprey)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Hyperoartia;Petromyzontiformes; Petromyzontidae; Petromyzon.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the glucagon family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level
Protein Length	160 Amino acids
Molecular weight	18042
References	1  PubMed abstract 10555286 2  PubMed abstract 8405897
Domain Name	Hormone_2
Hormone Name	Glucagon-1
Mature Hormone Sequence	HSEGTFTSDYSKYLENKQAKDFVRWLMNA
Position of mature hormone in Pre-Hormone protein	29 Residues from position (43-71)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 2

HMRbase accession number	10246
Swiss-prot Accession number	Q91971 (Sequence in FASTA format)
Description	Glucagon-1 precursor (Glucagon I) [Contains: Glicentin-relatedpolypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2)].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the glucagon family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level
Protein Length	178 Amino acids
Molecular weight	20034
References	1  PubMed abstract 7776976
Domain Name	Hormone_2
Hormone Name	Glucagon-1
Mature Hormone Sequence	HSEGTFSNDYSKYQEERMAQDFVQWLMNS
Position of mature hormone in Pre-Hormone protein	29 Residues from position (52-80)
Receptor	N/A
Gene ID	100136745
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 3

HMRbase accession number	10248
Swiss-prot Accession number	P81026 (Sequence in FASTA format)
Description	Glucagon-1 (Glucagon I).
Source organism	Oreochromis niloticus (Nile tilapia) (Tilapia nilotica)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Tilapiini;Oreochromis.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the glucagon family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level
Protein Length	36 Amino acids
Molecular weight	4252
References	1  PubMed abstract 7656183
Domain Name	Hormone_2
Hormone Name	Glucagon-1
Mature Hormone Sequence	HSEGTFSNDYSKYLEDRKAQDFVRWLMNNKRSGAAE
Position of mature hormone in Pre-Hormone protein	36 Residues from position (1-36)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 4

HMRbase accession number	11069
Swiss-prot Accession number	P01278 (Sequence in FASTA format)
Description	Glucagon-1 precursor (Glucagon I) [Contains: Glicentin-relatedpolypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1(Glucagon-like peptide I)].
Source organism	Lophius americanus (American goosefish) (Anglerfish)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Paracanthopterygii; Lophiiformes; Lophiidae; Lophius.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the glucagon family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis.
Protein Length	124 Amino acids
Molecular weight	14165
References	1  PubMed abstract 7043459 2  PubMed abstract 6165720 3  PubMed abstract 3058456
Domain Name	Hormone_2
Hormone Name	Glucagon-1
Mature Hormone Sequence	HSEGTFSNDYSKYLEDRKAQEFVRWLMNN
Position of mature hormone in Pre-Hormone protein	29 Residues from position (53-81)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 5

HMRbase accession number	11071
Swiss-prot Accession number	P07449 (Sequence in FASTA format)
Description	Glucagon-1 precursor [Contains: Glucagon-1; Glucagon-like peptide 1-1](Fragment).
Source organism	Oncorhynchus kisutch (Coho salmon)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the glucagon family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level
Protein Length	68 Amino acids
Molecular weight	7819
References	1  PubMed abstract 3520699
Domain Name	Hormone_2
Hormone Name	Glucagon-1
Mature Hormone Sequence	HSEGTFSNDYSKYQEERMAQDFVQWLMNS
Position of mature hormone in Pre-Hormone protein	29 Residues from position (1-29)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated