A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21292 |
| Swiss-prot Accession number | Q9PVE2 (Sequence in FASTA format) |
| Description | RecName: Estrogen receptor beta;ER-beta;Alternative Name: Nuclear receptor subfamily 3 group A member 2; |
| Source organism | Sturnus vulgaris (Starling) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Passeriformes; Sturnidae; Sturnus. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Brain, pituitary, skeletal muscle, liver, adrenal, kidney, intestine and ovary. |
| Post translational modification | N/A |
| Function | Binds estrogens with an affinity similar to that of ER- alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Locally synthesized estrogens may act via ER beta, in addition to ER alpha, to mediate seasonal or developmental effects on nearby song nuclei. |
| Protein Length | 554 Amino acids |
| Molecular weight | 62174 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 10499520 |
| Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |