| HMRbase accession number | 21193 |
| Swiss-prot Accession number | Q9NSD7 (Sequence in FASTA format) |
| Description | Relaxin-3 receptor 1 (RLN3 receptor 1) (Relaxin family peptidereceptor 3) (Somatostatin- and angiotensin-like peptide receptor) (Gprotein-coupled receptor SALPR) (GPCR135). |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Cell membrane; Multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis. |
| Post translational modification | N/A |
| Function | Receptor for relaxin-3. Binding of the ligand inhibit cAMP accumulation. |
| Protein Length | 469 Amino acids |
| Molecular weight | 51124 |
| Domain Name | N/A |
| References | 1 PubMed abstract 10806363
2 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
3 PubMed abstract 14522968
4 PubMed abstract 15489334
|
| Hormone | Q8WXF3 Detail in HMRbase
|
| Gene ID | 51289 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | |
A database of hormones and their receptors