A database of hormones and their receptors

Peptide Hormone

HMRbase accession number	10342
Swiss-prot Accession number	Q925Q4 (Sequence in FASTA format)
Description	Glycoprotein hormone alpha-2 precursor (Thyrostimulin subunit alpha).
Source organism	Rattus norvegicus (Rat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular location	Secreted protein (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the glycoprotein hormones subunit alpha family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Stimulates the thyroid. Binds and activates THSR, leads to increased cAMP production
Protein Length	130 Amino acids
Molecular weight	14199
References	1 Dasovich M., Ching A., Lok S., Sheppard P., Webster P.; "A novel cysteine knot protein expressed in pancreatic acinar cells."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
Domain Name	N/A
Hormone Name	Glycoprotein hormone alpha-2
Mature Hormone Sequence	LEAAVPIPGCHLHPFNVTVRSDRHGTCQGSHVAQACVGHCESSAFPSRYSVLVASGYRHNITSVSQCCTISSLKKVRVWLHCVGNQRGELEIFTARACQCDMCRLSRY
Position of mature hormone in Pre-Hormone protein	108 Residues from position (23-130)
Receptor	P21463 Detail in HMRbase
Gene ID	171158
PDB ID	N/A
Drugpedia	wiki
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