A database of hormones and their receptors
Receptor

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HMRbase accession number21420
Swiss-prot Accession numberQ8HYL6 (Sequence in FASTA format)
DescriptionPeroxisome proliferator-activated receptor alpha;PPAR-alpha;Alternative Name: Nuclear receptor subfamily 1 group C member 1
Source organismPhascolarctos cinereus (Koala)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Diprotodontia; Phascolarctidae; Phascolarctos.
Subcellular locationNucleus (By similarity)
Developmental StageN/A
Similarity Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue SpecificityN/A
Post translational modification N/A
Function Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids (By similarity).
Protein Length468 Amino acids
Molecular weight52199
Domain NameHormone_recep  zf-C4  
References----
HormoneDetail in HMRbase   
Detail in HMRbase   
Gene IDN/A
PDB IDN/A
Drugpediawiki
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