A database of hormones and their receptors
Receptor

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HMRbase accession number22995
Swiss-prot Accession numberQ6AXS4 (Sequence in FASTA format)
DescriptionRenin receptor;Alternative Name: Renin/prorenin receptor;Alternative Name: ATPase, H(+)-transporting, lysosomal accessory protein 2;Alternative Name: ATPase, H(+)-transporting, lysosomal-interacting protein 2;Precursor
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationMembrane; Single-pass type I membrane protein (Potential)
Developmental StageN/A
Similarity N/A
Tissue SpecificityN/A
Post translational modification Phosphorylated (By similarity).
Function Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) (By similarity).
Protein Length350 Amino acids
Molecular weight39082
Domain NameRenin_r  
References1  PubMed abstract 15489960
2  PubMed abstract 15489334
HormoneP08424   Detail in HMRbase   
Gene IDN/A
PDB IDN/A
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