A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21261 |
| Swiss-prot Accession number | P19785 (Sequence in FASTA format) |
| Description | RecName: Estrogen receptor;ER;Alternative Name: Estradiol receptor;Alternative Name: ER-alpha;Alternative Name: Nuclear receptor subfamily 3 group A member 1; |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Nucleus (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | N/A |
| Post translational modification | Phosphorylated by cyclin A/CDK2 (By similarity). |
| Function | Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues (By similarity). |
| Protein Length | 599 Amino acids |
| Molecular weight | 66955 |
| Domain Name | Hormone_recep Oest_recep zf-C4 |
| References | 1 PubMed abstract 2484714 2 PubMed abstract 16141072 3 PubMed abstract 10899303 4 PubMed abstract 17595322 5 PubMed abstract 8999954 6 PubMed abstract 11226831 7 PubMed abstract 9192892 8 PubMed abstract 10788465 9 PubMed abstract 15140878 10 PubMed abstract 15988012 |
| Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
| Gene ID | 13982 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |