A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21509 |
| Swiss-prot Accession number | P13053 (Sequence in FASTA format) |
| Description | Vitamin D3 receptor;VDR;Alternative Name: 1,25-dihydroxyvitamin D3 receptor;Alternative Name: Nuclear receptor subfamily 1 group I member 1 |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Detected in intestine and kidney. |
| Post translational modification | N/A |
| Function | Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Plays a central role in calcium homeostasis. |
| Protein Length | 423 Amino acids |
| Molecular weight | 47814 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 2849110 2 PubMed abstract 2829212 3 PubMed abstract 10866662 4 PubMed abstract 15065852 5 PubMed abstract 17227670 |
| Hormone | Detail in HMRbase Detail in HMRbase |
| Gene ID | 24873 |
| PDB ID | 1RJK 1RK3 1RKG 1RKH 2O4R |
| Drugpedia | wiki |
| Comments |