A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number11369
Swiss-prot Accession numberP04808 (Sequence in FASTA format)
DescriptionProrelaxin H1 precursor [Contains: Relaxin B chain; Relaxin A chain].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityProstate. Not expressed in placenta, decidua or ovary
Post translational modificationN/A
Function Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix
Protein Length185 Amino acids
Molecular weight21146
References1  PubMed abstract 6548702
2  PubMed abstract 6298628
3  PubMed abstract 15164053
4  PubMed abstract 15489334
5  PubMed abstract 8735594
6  PubMed abstract 10601981
Domain NameInsulin  
Hormone NameRelaxin B chain
Mature Hormone SequenceVAAKWKDDVIKLCGRELVRAQIAICGMSTWS
Position of mature hormone in Pre-Hormone protein31 Residues from position (23-53)
ReceptorQ9HBX9   Detail in HMRbase   
Q8WXD0    Detail in HMRbase   
Gene ID6013      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 2

HMRbase accession number11370
Swiss-prot Accession numberP04808 (Sequence in FASTA format)
DescriptionProrelaxin H1 precursor [Contains: Relaxin B chain; Relaxin A chain].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityProstate. Not expressed in placenta, decidua or ovary
Post translational modificationN/A
Function Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix
Protein Length185 Amino acids
Molecular weight21146
References1  PubMed abstract 6548702
2  PubMed abstract 6298628
3  PubMed abstract 15164053
4  PubMed abstract 15489334
5  PubMed abstract 8735594
6  PubMed abstract 10601981
Domain NameInsulin  
Hormone NameRelaxin A chain
Mature Hormone SequencePYVALFEKCCLIGCTKRSLAKYC
Position of mature hormone in Pre-Hormone protein23 Residues from position (163-185)
ReceptorQ9HBX9   Detail in HMRbase   
Q8WXD0    Detail in HMRbase   
Gene ID6013      
PDB IDN/A
Drugpediawiki
Comments