A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21280 |
| Swiss-prot Accession number | O93511 (Sequence in FASTA format) |
| Description | RecName: Estrogen receptor beta;ER-beta;Alternative Name: Nuclear receptor subfamily 3 group A member 2; |
| Source organism | Coturnix coturnix japonica (Japanese quail) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Perdicinae; Coturnix. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | A high expression is seen in the telencephalon, diencephalon, pituitary, testis and kidneys but little or no expression is seen in the cerebellum, pectoral muscle and adrenal gland. |
| Post translational modification | N/A |
| Function | Binds estrogens with an affinity similar to that of ER- alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. |
| Protein Length | 472 Amino acids |
| Molecular weight | 53411 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 9760113 |
| Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |